- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Retinopathy of Prematurity Studies
- Ocular Diseases and Behçet’s Syndrome
- Optical Coherence Tomography Applications
- Cardiovascular Health and Disease Prevention
- Non-Invasive Vital Sign Monitoring
- Ocular Surface and Contact Lens
- Cerebrovascular and Carotid Artery Diseases
- Ophthalmology and Visual Health Research
- Acute Ischemic Stroke Management
- Renal and Vascular Pathologies
- Connexins and lens biology
- Neonatal Respiratory Health Research
- Ocular and Laser Science Research
- Clinical Laboratory Practices and Quality Control
- Retinal Development and Disorders
- Neonatal and fetal brain pathology
- Multiple Sclerosis Research Studies
- Obstructive Sleep Apnea Research
Los Angeles Medical Center
2022-2025
Kaiser Permanente
2022-2025
Southern California Eye Institute
2009-2023
University of Southern California
2011-2023
Keck Hospital of USC
2020
Southern California University for Professional Studies
2020
University of California, Los Angeles
2001-2016
LAC+USC Medical Center
2013
Doheny Eye Institute
2009-2013
Oklahoma State University
2010
Importance While early detection of glaucoma is vital to prevent irreversible vision loss, there are sparse data on the effectiveness referrals and methods establish evidence-based referral guidelines in large, diverse populations. Objective To assess prevalence risk factors for diagnosed loss follow-up among adult patients aged 18 40 years after a new diagnosis referable (ie, with or suspected glaucoma). Design, Setting, Participants This retrospective cohort study included presenting...
The myeloperoxidase system of neutrophils uses hydrogen peroxide and chloride to generate hypochlorous acid, a potent bactericidal oxidant in vitro . In mouse model polymicrobial sepsis, we observed that mice deficient were more likely than wild-type die from infection. Mass spectrometric analysis peritoneal inflammatory fluid septic detected elevated concentrations 3-chlorotyrosine, characteristic end product the system. Levels 3-chlorotyrosine did not rise myeloperoxidase-deficient mice....
Purpose: To quantify retinal microvasculature within the macular ganglion cell-inner plexiform layer (GCIPL) in primary open-angle glaucoma (POAG) and normal eyes, determine association of vessel parameters with structural functional measures, report diagnostic accuracy parameters. Methods: POAG patients underwent 6×6 mm macula scans [Angioplex optical coherence tomography angiography (OCTA); Cirrus HD-OCT 5000]; Humphrey Field Analyzer II-i 24-2 visual field (VF). Prototype software...
PurposeTo determine the intraocular pressure (IOP) reduction of various trabecular procedures (a form minimally invasive glaucoma surgery [MIGS]) combined with cataract compared alone, to compare safety procedures, and highlight patient characteristics that may favor one procedure over another.MethodsA search English-language peer-reviewed literature in PubMed database was initially conducted February 2021 updated April 2023. This yielded 279 articles. Twenty studies met initial inclusion...
Uveitis is defined as a collection of syndromes involving intraocular inflammation which can lead to pain, tissue damage, and vision loss. Ophthalmic surgery in uveitis patients be challenging due inflammation-induced fibrosis scarring. Trabeculectomy implantation glaucoma drainage devices (aqueous shunts) have been used surgical management uveitic glaucoma, however there paucity literature examining the comparative results these entities this unique setting. The purpose retrospective study...
To quantify peripapillary microvasculature within the retinal nerve fiber layer (RNFL) in primary open-angle glaucoma (POAG) and normal eyes, determine association of perfusion parameters with structural functional measures, report diagnostic accuracy parameters.POAG patients underwent 6×6 mm2 optic head scans (Angioplex optical coherence tomography angiography [OCTA]; Cirrus HD-OCT 5000) Humphrey Field Analyzer II-i 24-2 visual field (VF) testing. Prototype software performed semiautomatic...
To compare the diagnostic ability of vessel parameters in macular and peripapillary regions measured using spectral-domain optical coherence tomography angiography (SD-OCTA) differentiating primary open-angle glaucoma (POAG) from healthy eyes.POAG patients subjects underwent 6 × 6-mm scans centered on macula optic nerve head. Commercially available automatic segmentation created en face images SD-OCTA superficial retinal layer (SRL) (m) (cp) regions. Vessel area density (VAD), skeleton...
<h3>Importance</h3> Uncorrected refractive error (RE) is a leading cause of visual impairment, and variations in ocular anatomy determine RE. The unique determinants RE Chinese American individuals have not been studied previously. <h3>Objective</h3> To report population 50 years older Monterey Park, California. <h3>Design, Setting, Participants</h3> Eye Study, population-based, cross-sectional study, was conducted from February 1, 2010, through October 31, 2013, with this particular data...
Objective To compare intrasession repeatability versus intersession reproducibility of the peripapillary vessel parameters using optical microangiography–based coherence tomography angiography (OCTA) in non-glaucomatous and glaucomatous eyes. Methods In an observational, longitudinal study, OCTA scans were collected to evaluate within-eye coefficient variation (CV W ) intraclass correlation (ICC). Images quantified a custom research–oriented quantification software calculating area density...
To quantify interquadrant differences in anterior chamber angle (ACA) configuration assessed on gonioscopy, EyeCam, and segment optical coherence tomography (AS-OCT) a cohort of Chinese Americans.Subjects aged 50 years or older were recruited from the American Eye Study (CHES), population-based epidemiologic study Los Angeles, CA. Each subject underwent complete ocular exam, including AS-OCT, under dark ambient lighting. Gonioscopy AS-OCT imaging EyeCam image grading performed by trained...