A5015987166- Gut microbiota and health
- Microbial Community Ecology and Physiology
- Probiotics and Fermented Foods
- Pharmaceutical and Antibiotic Environmental Impacts
- Diet and metabolism studies
- Clostridium difficile and Clostridium perfringens research
- Environmental DNA in Biodiversity Studies
- Ginseng Biological Effects and Applications
- Food Quality and Safety Studies
- Bacteriophages and microbial interactions
- Mycobacterium research and diagnosis
- Agriculture, Soil, Plant Science
- Antibiotic Resistance in Bacteria
- Methane Hydrates and Related Phenomena
- Ginger and Zingiberaceae research
- Neuroendocrine Tumor Research Advances
- Neonatal Respiratory Health Research
- Microbial Metabolism and Applications
- Freezing and Crystallization Processes
- Palliative Care and End-of-Life Issues
- Microencapsulation and Drying Processes
- Clinical Nutrition and Gastroenterology
- Seaweed-derived Bioactive Compounds
- Barrier Structure and Function Studies
- Anaerobic Digestion and Biogas Production
Jeju National University
2015-2024
Institute for Basic Science
2020-2021
Seoul Medical Center
2018
Soonchunhyang University
2011
We investigated the anti-obesity effects of potential prebiotic, laminarin, on mice fed a high-fat diet. A metagenomics approach was applied to characterize ecological and functional differences gut microbiota among normal diet (CTL), (HFD), laminarin-supplemented (HFL). The HFL showed slower weight gain than HFD during laminarin-feeding period, but rate increased after termination laminarin supplementation. Gut microbial community analysis clear between CTL mice, whereas were two. higher...
Porphyra tenera (PT) is a functional seaweed food that has been reported for health benefits such as antioxidant, immunostimulant, anti-inflammation, and hepatoprotective effects. In this study, we investigated the effect of PT extracts on gut microbiota modulation in colitis-induced mice. The mice experiment was designed three groups including normal (CTL), dextran sodium sulfate (DSS)-fed mice, DSS plus extracts-fed (PTE). administrated through drinking water containing 1 week, extract...
Codium fragile (CF) is a functional seaweed food that has been used for its health effects, including immunostimulatory, anti-inflammatory, anti-obesity and anti-cancer activities, but the effect of CF extracts on obesity via regulation intestinal microflora still unknown. This study investigated effects gut microbiota diet-induced obese mice. C57BL/6 mice fed high-fat (HF) diet were given intragastrically 12 weeks. significantly decreased animal body weight size adipocytes, while reducing...
The necessity of nasogastric decompression after abdominal surgical procedures has been increasingly questioned for several years. Traditionally, is a mandatory procedure classical pancreaticoduodenectomy (PD); however, we still do not know whether or it necessary PD. present study was designed to assess the clinical benefit PD.Between July 2004 and May 2007, 41 consecutive patients who underwent PD were enrolled in this study. Eighteen tube (NGT) group 23 no NGT group.There differences...
Meat from black pigs (BP) is in high demand compared with that modern white pig (WP) breeds such as Landrace owing to its quality. However, the growth rate of slower than breeds. We investigated differences fecal microbial composition between and explore whether these differed their gut communities. The swine microbiota was using Illumina's MiSeq-based sequencing technology by targeting V4 region 16S rRNA gene. Our results showed significantly different two While WP shifted according stage,...
Since the banning of antibiotic growth promoters (AGPs), death livestock has been increased, thus there is a strong demand for AGP-alternatives. Modulation gut microbiota reported to affect host physiological functions and suggested be novel approach developing However, little understood about compared that humans. We conducted preliminary study provide fundamental information regarding regional differences in swine microbiota. Swine fecal samples were obtained from farms Jeju (n=40),...
Red beetroots, rich in betanin, may act as prebiotics and impact gut microbiota. Because the human microbiota is unique to each person, effectiveness of varies with enterotype. In this study, we hypothesized that effects red beetroot powder (RP) betanin pigment (BP) would differ depending on Fecal samples from 30 subjects were analyzed categorized into three enterotypes:
Abstract Various metabolic diseases caused by a high‐fat diet (HFD) are closely related to gut microbiota dysbiosis and epithelial barrier dysfunction. Polycan, type of β‐glucan, is effective in treating anti‐obesity HFD. However, the effect Polycan on damage still unknown. In this study, effects intestinal were investigated using HFD‐induced obese model mice. C57BL/6 mice fed HFD for 12 weeks treated with two different doses (250 500 mg/kg) orally administered during 9 12. supplementation...
The incidence of colorectal cancer is rapidly growing in Korea, due to increasingly westernized dietary. We investigated the inhibitory effects Citrus grandis extracts rich polymethoxylated flavones cancer. CGDF treatment changed ratio pro-apoptotic and anti-apoptotic Bcl-2 family proteins generated ROS. could promote release cytochrome c into cytosol by activating expression caspases decreasing IAPs. ROS may initiate upstream signaling apoptotic pathway. inhibited growth xenograft tumors...
When used for amplicon sequencing, Illumina platforms produce more than hundreds of sequence artefacts, which affects operational taxonomic units based analyses such as differential abundance and network analyses. Nevertheless it has become a major tool fecal microbial community analysis. In addition, results from sequence-based analysis vary depending on conditions samples (i.e., freshness, time storage quantity). We investigated if freeze-drying could improve quality data. Our showed...