A5074343057- Gut microbiota and health
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Community Ecology and Physiology
- Antibiotic Resistance in Bacteria
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Gastrointestinal motility and disorders
- Agriculture, Soil, Plant Science
- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- Mycobacterium research and diagnosis
- Environmental DNA in Biodiversity Studies
- Genomics and Phylogenetic Studies
- Wastewater Treatment and Nitrogen Removal
- Aquaculture disease management and microbiota
- Escherichia coli research studies
- Nutrition, Health and Food Behavior
- Ginseng Biological Effects and Applications
- Microbial Metabolites in Food Biotechnology
- Food composition and properties
- Dietary Effects on Health
- Digestive system and related health
- Methane Hydrates and Related Phenomena
- Fecal contamination and water quality
- Molecular Biology Techniques and Applications
Chungbuk National University
2023-2024
Jeju National University
2014-2023
University of Minnesota
2010-2014
Biotechnology Institute
2011-2014
Institute for Soil, Climate and Water
2013
University of Minnesota System
2013
Institute of Plant Biology and Biotechnology
2013
Gwangju Institute of Science and Technology
2007-2011
Seoul National University
2010
Gwangju University
2010
Fecal microbiota transplantation (FMT) is becoming a more widely used technology for treatment of recurrent Clostridum difficile infection (CDI). While previous treatments fresh fecal slurries as source FMT, we recently reported the successful use standardized, partially purified and frozen to treat CDI. Here report that high-throughput 16S rRNA gene sequencing showed stable engraftment gut following FMT using bacteria from healthy donor. Similar bacterial taxa were found in...
Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (CDI) that often fails standard antibiotic therapy. Despite its widespread recent use, however, little known about the stability of fecal following FMT.Here we report on short- and long-term changes provide kinetic visualization composition in patients with multiply CDI were refractory to therapy treated using FMT. samples collected from four before up 151 days after FMT, daily...
Journal Article Application of Illumina next‐generation sequencing to characterize the bacterial community Upper Mississippi River Get access C. Staley, Staley BioTechnology Institute University Minnesota St. Paul MN USA Search for other works by this author on: Oxford Academic Google Scholar T. Unno, Unno Applied Bioinformatics Lab (ABL) Jeju National 66 Jejudaehakno Jeju‐si Jeju‐do 690‐756 Republic KoreaBioTechnology T.J. Gould, Gould USABiology Program Minneapolis B. Jarvis, Jarvis...
Abstract Background The sinorhizobia are amongst the most well studied members of nitrogen-fixing root nodule bacteria and contribute substantial amounts fixed nitrogen to biosphere. While alfalfa symbiont Sinorhizobium meliloti RM 1021 was one first rhizobial strains be completely sequenced, little information is available about genomes this large diverse species group. Results Here we report draft assembly annotation 48 comprising five genospecies. S. medicae taxonomically related, they...
Clostridium difficile is an opportunistic human intestinal pathogen, and C. infection (CDI) one of the main causes antibiotic-induced diarrhea colitis. One successful approach to combat CDI, particularly recurrent form through transplantation fecal microbiota from a healthy donor infected patient. In this study we investigated distal gut microbial communities three CDI patients before after transplantation, compared these composition donor's microbiota. We utilized phylogenetic Microbiota...
While many current microbial source tracking (MST) methods rely on the use of specific molecular marker genes to identify sources fecal contamination, these often fail determine all point and nonpoint contributors inputs into waterways. In this study, we developed a new library-dependent MST method that uses pyrosequencing-derived shared operational taxonomy units (OTUs) define contamination in A total 56,841 pyrosequencing reads 16S rDNA obtained from feces humans animals were evaluated...
We investigated the anti-obesity effects of potential prebiotic, laminarin, on mice fed a high-fat diet. A metagenomics approach was applied to characterize ecological and functional differences gut microbiota among normal diet (CTL), (HFD), laminarin-supplemented (HFL). The HFL showed slower weight gain than HFD during laminarin-feeding period, but rate increased after termination laminarin supplementation. Gut microbial community analysis clear between CTL mice, whereas were two. higher...
Resistance to both chemotherapy and radiation therapy is frequent in triple-negative breast cancer (TNBC) patients. We established treatment-resistant TNBC MDA-MB-231/IR cells by irradiating the parental MDA-MB-231 25 times with 2 Gy irradiation investigated molecular mechanisms of acquired resistance. The resistant were enhanced migration, invasion, stem cell-like characteristics. Pathway analysis Database for Annotation, Visualization Integrated Discovery revealed that NF-κB pathway, TNF...
Abstract Increasing evidence indicates that alterations in gut microbiota are associated with mammalian development and physiology. The has been proposed as an essential player metabolic diseases including brain health. This study aimed to determine the impact of probiotics on degenerative changes cognitive behavior. Assessment various behavioral physiological functions was performed using Y-maze tests, wheel running accelerated rotarod balance beam forced swimming tests (FSTs), adult mice...
(1) Background: The intestinal microbiota plays an essential role in maintaining the host’s health. Dysbiosis of equine hindgut can alter fermentation patterns and cause metabolic disorders. (2) Methods: This study compared fecal composition horses with disease their healthy counterparts living Korea using 16S rRNA sequencing from samples. A total 52 samples were collected divided into three groups: large (n = 20), small 8), 24). (3) Results: Horses diseases had fewer species a less diverse...
Metabolic syndrome is associated with usual dietary patterns that may be involved in enterotypes. We aimed to understand the potential relationship of enterotypes and influence metabolic Koreans. Using Korea National Health Nutrition Examination Survey (KNHANES)-VI 2014, parameters were also analyzed among classified by principal component analysis Korean adults. The fecal microbiota data 1199 adults collected 2014 obtained from Centers for Disease Control Prevention. Enterotypes based on...