- Nutrition and Health in Aging
- Body Composition Measurement Techniques
- Cardiovascular and exercise physiology
- Cardiovascular Health and Disease Prevention
- Adipose Tissue and Metabolism
- Heart Rate Variability and Autonomic Control
- Physical Activity and Health
- Muscle metabolism and nutrition
- Cardiovascular Disease and Adiposity
- Sports Performance and Training
- Nutritional Studies and Diet
- Frailty in Older Adults
- Adipokines, Inflammation, and Metabolic Diseases
- Exercise and Physiological Responses
- Genetics and Physical Performance
- Stroke Rehabilitation and Recovery
- Blood Pressure and Hypertension Studies
- Acute Ischemic Stroke Management
- Apelin-related biomedical research
- Thermoregulation and physiological responses
- Muscle Physiology and Disorders
- Cardiovascular Function and Risk Factors
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Sports injuries and prevention
- Obesity, Physical Activity, Diet
Ritsumeikan University
2015-2024
Waseda University
2006-2019
Miyoshi Kasei (Japan)
2015-2019
University of Hawaiʻi at Mānoa
2017
Seikei University
2016
Kobe University
2015-2016
Tokyo Medical University
2016
Doshisha University
2016
Kyoto Medical Center
2016
National Institute of Infectious Diseases
2007-2016
Aim To examine the relationship between calf circumference and muscle mass, to evaluate suitability of as a surrogate marker mass for diagnosis sarcopenia among middle‐aged older J apanese men women. Methods A total 526 adults aged 40–89 years participated in present cross‐sectional study. The maximum was measured standing position. Appendicular skeletal using dual‐energy X ‐ray absorptiometry, index calculated appendicular divided by square height (kg/m 2 ). cut‐off values were defined less...
Habitual moderate-to-vigorous-intensity physical activity attenuates arterial stiffening. However, it is unclear whether light also It has the same effects in fit and unfit individuals. This cross-sectional study was performed to determine relationships between amount of determined with a triaxial accelerometer stiffness. A total 538 healthy men women participated this study. Subjects each age category were divided into either high-light or low-light groups based on daily time spent...
Aging is associated with low-grade inflammation. The benefits of regular exercise for the elderly are well established, whereas less known about impact low-intensity resistance on inflammation in elderly. Twenty-one women (mean age ± SD, 85.0 4.5 years) participated 12 weeks training. Muscle thickness and circulating levels C-reactive protein (CRP), serum amyloid A (SAA), heat shock (HSP)70, tumor necrosis factor (TNF)-α, interleukin (IL)-1, IL-6, monocyte chemotactic (MCP-1), insulin,...
To elucidate the effects of endurance training on circulating irisin levels in young and middle-aged/older adults, to determine association between training-induced alteration reduction body fat. Twenty-five healthy (age 21 ± 1 years; 16 men, 9 women) 28 adults 67 8 12 participated study. Each age cohort was divided into two groups: endurance-training group (14 young, 14 middle-aged/older) control group. Subjects groups completed an 8-week program (cycling at 60-70% peak oxygen uptake...
Our previous study showed that relatively low-intensity (approximately 50% one-repetition maximum [1RM]) resistance training (knee extension) with slow movement and tonic force generation (LST) caused as significant an increase in muscular size strength high-intensity 80% 1RM) normal speed (HN). However, examined only local effects of one type exercise on knee extensor muscles. The present was performed to examine whether a whole-body LST regimen is effective hypertrophy gain HN training....
Flexibility is one of the components physical fitness as well cardiorespiratory and muscular strength endurance. has long been considered a major component in preventive treatment musculotendinous strains. The present study investigated new aspect flexibility. Using cross-sectional design, we tested hypothesis that less flexible body would have arterial stiffening. A total 526 adults, 20 to 39 yr age (young), 40 59 (middle-aged), 60 83 (older), participated this study. Subjects each category...
Aging-induced arterial stiffening is reduced by aerobic exercise training, and elevated production of nitric oxide (NO) participates in this effect. Adropin a regulator endothelial NO synthase release, circulating adropin level decreases with age. However, the effect habitual on levels healthy middle-aged older adults remains unclear. We sought to determine whether serum associated training-induced changes stiffness. First, cross-sectional study, we investigated association between both...
The authors investigated the effects of low-intensity resistance training on muscle size and strength in older men women. Thirty-five participants (age 59–76 yr) were randomly assigned to 2 groups performed (50% 1-repetition maximum) knee-extension -flexion exercises with either slow movement tonic force generation (LST; 3-s eccentric, concentric, 1-s isometric actions no rest between repetitions) or normal speed (LN; concentric eccentric rests twice a week for 12 wk (2-wk preparation 10-wk...
Aging-induced deterioration of arterial stiffness is decreased by regular exercise, and increased nitric oxide (NO) production participates in this effect. Apelin regulates endothelial NO synthase cells, promoting production. However, the effect aerobic exercise training on circulating apelin levels healthy middle-aged older adults remains unknown. Accordingly, study aimed to clarify effects concentrations adults. Thirty-four subjects (67.0 ± 1.3 years) were randomly divided into two groups:...
Aim The present study investigated whether a slow movement protocol can be applied to resistance training using bodyweight. In addition, the intervention program combined plyometric exercise with improve physical function overall. Methods A total of 39 active elderly adults participated in 16‐week intervention. consisted five exercises and four their own bodyweight single set for each exercise. Participants were assigned one two experimental groups. One group carried out tonic force...
The aim of this study was to investigate the association between anthropometric measurements sarcopenic obesity and all-cause mortality.The included 2309 Japanese-American men ages 71 93 y. Mortality data were available for up 24 y follow-up. Sarcopenic defined by three patterns indexes (body mass index [BMI], percent body fat [%BF] waist circumference [WC]) skeletal muscle estimated measurements.Of participants, 2210 deaths reported during mean follow-up period 11.7 Risk death significantly...
This study aimed to clarify whether muscle-derived irisin secretion induced by aerobic exercise training is involved in reduction of arterial stiffness via nitric oxide (NO) productivity obesity. In animal study, 16 Otsuka Long-Evans Tokushima Fatty (OLETF) rats with obesity were randomly divided into 2 groups: sedentary control (OLETF-CON) and 8-week treadmill (OLETF-EX) groups. human 15 subjects completed for 45 min at 60%–70% peak oxygen uptake intensity 3 days/week. As a result...
Resistance training is a popular mode of exercise, but may result in stiffening the central arteries. Changes carotid artery diameter were determined using cold pressor test (CPT), which results production nitric oxide via sympathetic activation and one novel methods available for assessing endothelial function artery. To investigate effect resistance on function, we designed cross‐sectional study arterial vasoreactivity to CPT men participating regular with increased stiffness compared...
Aging-induced elevation in C1q secretion activates the Wnt signaling pathway muscles, leading to development of muscle fibrosis. However, association between serum level and mass strength remains unclear humans. The aim study was elucidate whether is associated with aging- resistance training-induced changes strength. First, a cross-sectional study, we investigated 131 healthy subjects, aged 20-81 yr. Second, an intervention examined effects on 12 wk training 11 older adults (60-81 yr). In...
This study aimed to investigate whether the overlap of physical, cognitive, and social frailty affects Ikigai in community-dwelling Japanese older adults. Participants were 116 adult men women. Associations with falls, daily living assessment, analyzed by group comparisons multivariate analyses. Physical, associated risk falls Ikigai. An increase number category overlaps was an increased decrease Multivariate analyses adjusted for confounding factors showed that physical cognitive related In...
Sarcopenic obesity is the co‐existence of and sarcopenia in individuals aged 40–75 years. The Japanese Working Group on Obesity has developed diagnostic criteria tailored for population, considering their unique characteristics compared with European populations. Our algorithm consists two steps: screening diagnosis. mandates using waist circumference and/or body mass index (BMI) based national standards, while involves “finger ring test” addition to Asian Sarcopenia 2019 criteria. final...
Age-related reduction in bone mineral density (BMD) is generally accelerated women after menopause, and could be even more pronounced individuals with sarcopenia. Light-load power training a low number of repetitions would increase BMD, significantly reducing loss at risk osteoporosis. This study investigated the effects low-repetition, light-load on BMD Japanese postmenopausal sarcopenia.The group (n = 7) followed progressive protocol that increased load weighted vest, for two sessions per...
Serum levels of adropin, which enhances endothelial cell release nitric oxide (NO), are lower in obese patients. Although habitual aerobic exercise reduces arterial stiffness and adiposity, the relationship between these effects circulating adropin remains unclear. The purpose this study was to determine if serum level is associated with training on adiposity adults. In Experiment 1, we examined whether cardiorespiratory fitness, carotid β-stiffness, plasma nitrite/nitrate (NOx) level,...