A5006617124- Schizophrenia research and treatment
- Astro and Planetary Science
- Mental Health and Psychiatry
- Mental Health Research Topics
- Psychiatric care and mental health services
- Isotope Analysis in Ecology
- Child and Adolescent Psychosocial and Emotional Development
- Planetary Science and Exploration
- Functional Brain Connectivity Studies
- Atmospheric Ozone and Climate
- Psychotherapy Techniques and Applications
- Personality Disorders and Psychopathology
- Astrophysics and Star Formation Studies
- Mental Health Treatment and Access
- Behavioral and Psychological Studies
- Obsessive-Compulsive Spectrum Disorders
- Molecular Spectroscopy and Structure
- Epilepsy research and treatment
- Electroconvulsive Therapy Studies
- Autism Spectrum Disorder Research
- Click Chemistry and Applications
- Immunotherapy and Immune Responses
- Attention Deficit Hyperactivity Disorder
- Radiopharmaceutical Chemistry and Applications
- Cancer Immunotherapy and Biomarkers
University of Bern
2002-2025
International Space Science Institute
2024
University of Fribourg
2024
Universitäre Psychiatrische Dienste Bern
2001-2023
University Hospital of Zurich
2023
University Hospital of Bern
2010-2022
University Medical Center of the Johannes Gutenberg University Mainz
2021-2022
Johannes Gutenberg University Mainz
2021-2022
University Hospital Southampton NHS Foundation Trust
2018-2021
University of Southampton
2018
Ammonium hydrosulphide has long since been postulated to exist at least in certain layers of the giant planets. Its radiation products may be reason for red colour seen on Jupiter. Several ammonium salts, NH3 and an acid, have previously detected comet 67P/Churyumov-Gerasimenko. The acid H2S is fifth most abundant molecule coma 67P followed by NH3. In order look salt NH4+SH-, we analysed situ measurements from Rosetta/ROSINA Double Focusing Mass Spectrometer during Rosetta mission. appear...
Context. Isotopic abundances in comets are key to understanding and reconstructing the history origin of material Solar System. Data for deuterium-to-hydrogen (D/H) ratios water available several comets. However, no long-term studies D/H ratio a comet during its passage around Sun have been reported thus far. Linear alkanes important organic molecules that found on System bodies, including To date, processes their deuteration still poorly understood, only upper limits isotopic 13 C/ 12 C...
Objective: The efficacy of three newly developed cognitive social skills training programmes for residential, vocational and recreational functioning (experimental groups) were compared with a traditional programme (control group) referring to abilities, psychopathology generalisation effects. Method: One hundred five patients diagnosis schizophrenia or schizoaffective disorder according ICD‐10 criteria selected assigned the different treatment groups, using matching procedure. phase lasted...
Seventeen patients, treated for Wilson's disease (WD), underwent a set of neuropsychological tests and were compared with closely matched control group. There clear differences between the groups (chi 2-test, p less than 0.0001). Wilson patients only hepatic involvement, however, did not at all differ from their controls. neuropsychiatric signs differed controls on reasoning test (p = 0.0016), entire WD group perceptual speed task 0.0025). Compared to normal values, patients' means within...
ABSTRACT European Space Agency’s Rosetta spacecraft at comet 67P/Churyumov–Gerasimenko (67P) was the first mission that accompanied a over substantial fraction of its orbit. On board Orbiter Spectrometer for Ion and Neutral Analysis mass spectrometer suite to measure local densities volatile species sublimating from ices inside comet’s nucleus. Understanding nature these key goal Rosetta. We analysed primary cometary molecules 67P, namely H2O CO2, together with minor almost entire mission....
Abstract Gas and dust outbursts are recurring phenomena on comets, offering critical insights into their subsurface activities. On comet 67P/Churyumov-Gerasimenko, two distinct outburst types have been identified: CO2-dominated ”summer fireworks” near perihelion water-driven events often linked to cliff collapses outside the period. While thought originate from gas cavities, properties of these cavities remain poorly understood. In this study, we modelled outgassing dynamics velocities using...
Terrestrial (carbon-based) biochemistry relies on chemical functionality introduced by heteroatoms. Among them, the nitrogen atom (N) defines (bio)chemical properties of crucial building blocks life such as amino acids (AAs) and nucleobases (NBs). However, it has not been clear until today whether these Earth were synthesized from simple prebiotic molecules young planet itself or rather delivered impacting material. Comets only carry some most pristine original material in our Solar System,...
A time-of-flight mass spectrometer (TOF-MS) separates charged particles by their mass-per-charge ratio on the basis of transit times through an electric field. For accurate determination, ions must be guided from source inlet, ion-optical system, and onto detector as a beam with controlled, narrow opening angle. This requires careful dimensioning electrodes computation applied fields to control deflection achieve both spatial temporal focusing across entire plane. The primary goal this work...
ABSTRACT Dust and gas outbursts are recurrent cometary phenomena, playing a crucial role in shaping the coma. Proposed outburst trigger mechanisms include cliff collapse, pressure pockets, amorphous-to-crystalline phase transition of water ice; however, underlying processes remain inadequately understood. In this study, we analyse Rosetta/ROSINA data from multiple on comet 67P/Churyumov-Gerasimenko present evolution composition comet’s coma during events. We distinguish two distinct...
Context. Comets are considered to be remnants from the formation of Solar System. ESA’s Rosetta mission targeted comet 67P/Churyumov-Gerasimenko and was able record high-quality data on its chemical composition outgassing behaviour, including low abundances N 2 that observed correlated with H O CO in approximately a 63:37 ratio. Aims. In this work, thermal desorption behaviour O:CO ices studied laboratory investigate co-desorption within two most abundant cometary 67P derive desorbing...
Context. The ROSINA instrument on board the Rosetta spacecraft measured, among others, outgassing of noble gases from comet 67P/Churyumov–Gerasimenko. interpretation this dataset and unravelling underlying desorption mechanisms requires detailed laboratory studies. Aims. We aim to improve our understanding patterns, trapping, fractionation released H 2 O:CO -dominated ice 67P. Methods. In laboratory, films neon, argon, krypton, or xenon (Ne, Ar, Kr, Xe) mixed in CO :H O were prepared at 15...
The puzzling complexity of terrestrial biomolecules is driving the search for complex organic molecules in interstellar medium (ISM) and serves as a motivation many situ studies reservoirs extraterrestrial organics, from meteorites interplanetary dust particles to comets asteroids. Comet 67P/Churyumov-Gerasimenko (67P), best-studied comet date, has been visited accompanied 2 yr by European Space Agency’s Rosetta spacecraft. Around 67P’s perihelion under dusty conditions, high-resolution mass...
As Roder and colleagues propose, we have seen three eras in the development refinement of social skills training for individuals with schizophrenia. In 1960s, relied on use operant conditioning, as exemplified by token economy. Reinforcement contingencies succeeded activating patients negative symptoms improving their behavior. Contemporary psychiatric rehabilitation can profit from identification reinforcers to motivate anergic who lack insight participate actively community-based programs....
Background: Pemetrexed is an antifolate drug approved for maintenance and second-line therapy, and, in combination with cisplatin, first-line treatment of advanced nonsquamous non-small cell lung cancer. The side-effect profile includes fatigue, hematological gastrointestinal toxicity, increase hepatic enzymes, sensory neuropathy, pulmonary cutaneous toxicity various degrees. Case Report: We present the case a 58-year-old woman history Sharp's syndrome adenocarcinoma lung, who developed...
Hintergrund: Bislang herrscht ein erheblicher Mangel an Gruppentherapieverfahren für Patienten mit unterschiedlichen Persönlichkeitsstörungen. Vor diesem Hintergrund entwickelte unsere Arbeitsgruppe einen neuen manualisierten Therapieansatz, der schematherapeutische, emotionszentrierte, kognitive und verhaltenstherapeutische Methoden integriert, die «Schemazentrierte emotiv-behaviorale Therapie» (SET). Methoden: Randomisierter Kontrollgruppenvergleich zwischen SET einem Therapieverfahren zur...