Martin Sundqvist

ORCID: 0000-0003-3750-6075
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Galectins and Cancer Biology
  • Antibiotics Pharmacokinetics and Efficacy
  • Antibiotic Resistance in Bacteria
  • Bacterial Identification and Susceptibility Testing
  • Gastroesophageal reflux and treatments
  • Eosinophilic Esophagitis
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Pneumonia and Respiratory Infections
  • Gastric Cancer Management and Outcomes
  • Otolaryngology and Infectious Diseases
  • Bacterial Infections and Vaccines
  • Atrial Fibrillation Management and Outcomes
  • Caveolin-1 and cellular processes
  • Antimicrobial Resistance in Staphylococcus
  • Survey Methodology and Nonresponse
  • Ultrasound in Clinical Applications
  • Respiratory viral infections research
  • Obstructive Sleep Apnea Research
  • Bacterial Genetics and Biotechnology
  • Elasticity and Material Modeling
  • Cardiac pacing and defibrillation studies
  • Tracheal and airway disorders
  • Infective Endocarditis Diagnosis and Management

Stockholm South General Hospital
2017-2025

Karolinska Institutet
2017-2025

Örebro University
2024

Växjö Kommun
2014

Örebro University Hospital
2014

Abstract Aims The REDUCE-AMI trial showed that beta-blockers in patients with preserved left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) had no effect on mortality or cardiovascular outcomes. aim of this substudy was to evaluate whether global longitudinal strain (GLS) is a better prognostic marker than LVEF, and if have beneficial decreased GLS. Methods Results registry-based randomized clinical trial. Conventional echocardiographic parameters GLS were...

10.1093/ehjci/jeaf015 article EN cc-by-nc European Heart Journal - Cardiovascular Imaging 2025-01-15

The role of Helicobacter pylori (H. pylori) screening and eradication on reducing upper gastrointestinal bleeding (UGIB) complications after acute myocardial infarction (MI) is uncertain. HELicobacter Pylori to prevent in patients with MI (HELP-MI SWEDEHEART) trial aims determine whether systematic H. compared usual care reduces UGIB, mortality, cardiovascular outcomes MI. A cluster randomized, crossover, registry-based clinical using SWEDEHEART as platform for study population definition...

10.1016/j.ahj.2025.03.014 article EN cc-by American Heart Journal 2025-03-01

Potent antithrombotic therapy has significantly improved prognosis for patients with acute myocardial infarction (AMI), however, at a price of increased bleeding risk. Chronic gastric infection Helicobacter pylori (Hp) commonly causes upper gastrointestinal and is proposed as risk factor subsequent post AMI. The prevalence active Hp in current AMI population the feasibility screening part routine clinical care are unclear. To determine contemporary cohort to establish diagnosis MI care....

10.1016/j.ahj.2020.10.072 article EN cc-by American Heart Journal 2020-11-02

Study objectives Obstructive sleep apnea is common among patients with atrial fibrillation, but the prevalence and risk factors for fibrillation who are being investigated on suspicion of not well known. The aim study was to estimate suspected obstructive identify them. Methods 201 referred apnea. Patients without known were a standard 12-lead ECG at hospital short intermittent handheld recordings home, during 14 days. Results Atrial occurred in 13 subjects (6.5%), 12 61 men aged 60 years...

10.1371/journal.pone.0171575 article EN cc-by PLoS ONE 2017-02-08

ABSTRACT Common phenotypic methods for antimicrobial susceptibility testing (AST) of bacteria are slow, labor intensive, and display considerable technical variability. The QuickMIC system provides rapid AST using a microfluidic linear gradient. Here, we evaluate the performance at four different laboratories with regard to speed, precision, accuracy, reproducibility in comparison broth microdilution (BMD). Spiked ( n = 411) clinical blood cultures 148) were tested Gram-negative panel...

10.1128/jcm.00458-24 article EN cc-by Journal of Clinical Microbiology 2024-09-26

Helicobacter pylori (H. pylori) has been associated with cardiovascular diseases. The pro-inflammatory H. virulence factor cytotoxin-associated gene A (CagA) detected in serum exosomes of pylori-infected subjects and may exert systemic effects throughout the system. role CagA vascular calcification was hitherto unknown. aim this study to determine through human coronary artery smooth muscle cell (CASMC) osteogenic effector expression as well interleukin 1β secretion cellular calcification....

10.3390/ijms24065392 article EN International Journal of Molecular Sciences 2023-03-11

Myocardial infarction (MI) with obstructive coronary artery disease (MI-CAD) and MI in the absence of (MINOCA) affect different populations may have separate pathophysiological mechanisms, greater inflammatory activity MINOCA compared to MI-CAD. Helicobacter pylori (Hp) can cause systemic inflammation has been associated cardiovascular (CVD). We aimed investigate whether Hp infection is concentrations protein biomarkers CVD. In a case-control study, patients (n = 99) Sweden were included,...

10.3390/ijms241814143 article EN International Journal of Molecular Sciences 2023-09-15

Abstract Objectives Common phenotypic methods for antibiotic susceptibility testing (AST) of bacteria are slow, labour intensive and display considerable technical variability. The QuickMIC system provides rapid AST using a microfluidic linear gradient. Here we evaluate the performance at four different laboratories with regards to speed, precision, accuracy, reproducibility in comparison broth microdilution (BMD). Methods Spiked blood cultures (n=411) clinical (n=148) were tested Gram...

10.1101/2024.03.20.24304581 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2024-03-21

Background: Aortic stenosis (AS) is associated with increasing severity of diastolic dysfunction as measured by conventional echocardiographic grading. The parameterized filling (PDF) method can describe function mechanistically, analyzing using the physics classical mechanics for spring recoil. Purpose: To use PDF to how manifests in AS. Methods: Patients (n=73) undergoing echocardiography were included according AS varying (normal/mild AS: maximum Doppler velocity across aortic valve...

10.1101/2024.09.20.24313309 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-09-23
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