A5042598098- Genomics, phytochemicals, and oxidative stress
- Ginseng Biological Effects and Applications
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Pharmacogenetics and Drug Metabolism
- Healthcare and Venom Research
- Diverse Approaches in Healthcare and Education Studies
- RNA regulation and disease
- Dialysis and Renal Disease Management
- Traditional Chinese Medicine Studies
- Spinal Hematomas and Complications
- Microbial bioremediation and biosurfactants
- Cardiomyopathy and Myosin Studies
- Sulfur Compounds in Biology
- Biochemical and biochemical processes
- Plant chemical constituents analysis
- Garlic and Onion Studies
- Eicosanoids and Hypertension Pharmacology
- NF-κB Signaling Pathways
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Chromatography in Natural Products
- Cancer Treatment and Pharmacology
- Cervical and Thoracic Myelopathy
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Analysis
Changwon National University
2001-2025
Severance Hospital
2022
Yonsei University
2022
Kyung Hee University
2010-2013
Seoul St. Mary's Hospital
2006
Catholic University of Korea
2006
KT&G (South Korea)
1998
Illinois Institute of Technology
1996
Five pink-pigmented bacterial strains, isolated from human skin and classified within the genus Roseomonas , were examined. Among them, four identified as mucosa while strain OT10 T was deemed to be a potential novel species. Strain exhibited characteristics, such Gram-stain-negative, oxidase positive, motile, strictly aerobic rod shaped. The cells had multiple flagella at one end, arranged in lophotrichous pattern. predominant cellular fatty acids C 18:1 ω7c/C ω6c 2OH; ubiquinone (Q)-10...
Secondary mechanisms, including inflammation and microglia activation, serve as targets for the development application of pharmacological strategies in management spinal cord injury (SCI). Tetramethylpyrazine (TMP), an active ingredient Ligusticum wallichii (chuanxiong), has shown anti-inflammatory neuroprotective effects against SCI. However, it remains uncertain whether inflammation-suppressive TMP play a modulatory role over activation The present study investigated on pro-inflammatory...
1. The inhibitory effects of several naturally occurring flavonoids and related compounds oncytochrome P450-dependent 7-ethoxycoumarin O-deethylase(ECOD) the structure-activity relationships were studied in liver microsomes from rats treated with 3-methylcholanthrene (MC). 2. All (flavone, apigenin, chrysin, flavonol, fisetin, kaempferol, morin, myrisetin, quercetin, flavanone, hesperetin naringenin) inhibited microsomal ECOD activity following order: flavones > flavonols flavanones, mixed...
The acute and subacute hypoglycemic antihyperglycemic effects of drinkable ripe onion juice (Commercial product name is "Black Onion Extract") were investigated in normal streptozotocin-induced diabetic rats. For tests effects, (5 15 mL/kg b.w.) was administered by oral gavage to Sprague Dawley rats measurements fasting glucose levels tolerance performed. Tolbutamide used as a reference drug at single dose 250 mg/kg b.w. To test anti-hyper-glycemic activity, the per day for 7 consecutive...
Vitreoscilla cytochrome bo ubiquinol oxidase is similar in some properties to the Escherichia coli enzyme, but unlike latter, functions as a primary Na+ pump. When purified incorporated into liposomes made from phospholipids and energized with quinol substrate, it translocates Na+, not H+, across vesicle membrane. Since protonophores CCCP (carbonyl cyanide m-chlorophenylhydrazone) DTHB (3,5-di-tert-butyl-4-hydroxybenzaldehyde) stimulated pumping, unlikely that secondary effect due presence...
We aimed to suggest muscle mass-based criteria for using of the cystatin C test accurate estimated glomerular filtration rate (eGFR).We recruited 138 Korean subjects and evaluated eGFRcr (derived from Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) based on creatinine) was compared eGFRcys as reference value. The skeletal mass index (SMI) by bioelectrical impedance analysis (BIA) used representative mass. Calf circumference (CC) also evaluated. defined patients those with values...
Contact with antigen on T-cells is made via the T-cell receptor/CD3 complex plus CD28, resulting in production of cytokines including interleukin (IL)-2, IL-4 and interferon (IFN)-gamma. In particular, dysregulation IFN-gamma accounts part for organ-specific autoimmune diseases, allergic inflammation other chronic inflammatory disorders. The dried above-ground parts Schizonepeta tenuifolia Briq are used treatment common cold skin rashes observed dermatitis, psoriasis dermatological disorders...
본 연구는 RAW264.7 세포에서 lipopolysaccharide (LPS) 처리에 의한 염증매개인자의 유도에 대한 고려인삼 사포닌 분획인 20(S)-protopanaxadiol saponins (PDS)과 20(S)-protopanaxatriol (PTS)의 조절효능을 탐구하였다. 이를 위해 세포에 PDS 또는 PTS를 <TEX>$150{\mu}g/ml$</TEX>의 농도로 LPS (<TEX>$10{\mu}g/ml$</TEX> 처리 이전이나 이후 LPS와 동시에 처리하였으며, 처리된 nitric oxide (NO)의 방출량, 유도성 synthase (iNOS) 및 cyclooxygenase-2 (COX-2)의 발현 량을 분석하였다. PDS에 비하여 PTS는 처리하여 24시간 동안 배양했을 때 의해 유도된 NO의 생성을 강하게 감소시켰다. (<TEX>$10{\mu}g/ml$</TEX>를 2시간 처리한 후에 <TEX>$150{\mu}g/ml$</TEX> 처리하면 두 인삼...
When endoplasmic reticulum (ER) functions are perturbed, the ER induces several signaling pathways called unfolded protein response to reestablish homeostasis through three transmembrane proteins: inositol-requiring enzyme 1 (IRE1), PKR-like kinase (PERK), and activating transcription factor 6 (ATF6). Although it is important measure activity of ATF6 that can indicate status ER, no specific cell-based reporter assay currently available. Here, we report a new method for monitoring stress...
This research is about shared living facilities for the solitary elderly in Gyeonggi province (so called "Carnation House"), which was opened after 2013. These aim to help solving social problems of growing number elderly. The conducted from April 2014 October by using observation, measurement, photography, and interview methods. reviewed floor plan, area, accessibility, visual openness, furniture equipments. results are as follows: First, considering need rest area protection privacy,...
Objective : The purpose of this study is to report the effect Bee Venom Acua-Acupuncture Therapy patient Pes Anserine Bursitis by using DITI. Patient & Methods was 60-year-old woman who complained severe knee pain. She treated bee venom acuaacupuncture therapy. To estimate efficacy tratment, we used DITI, visual analog scale, joint check(ROM). Results In case, for 28 days. acua-acupuncture therapy efficiently relieved patient`s pain and improved ROM. DITI Visual scale also showed...