Hye Won Lee

ORCID: 0000-0002-6125-187X
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Cardiac Structural Anomalies and Repair
  • Mechanical Circulatory Support Devices
  • Anesthesia and Sedative Agents
  • Coronary Artery Anomalies
  • Anesthesia and Pain Management
  • Kawasaki Disease and Coronary Complications
  • Tracheal and airway disorders
  • Airway Management and Intubation Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Arrest and Resuscitation
  • Nausea and vomiting management
  • Congenital Diaphragmatic Hernia Studies
  • Anesthesia and Neurotoxicity Research
  • Cardiovascular Issues in Pregnancy
  • Cardiac Valve Diseases and Treatments
  • Cardiac Ischemia and Reperfusion
  • Spine and Intervertebral Disc Pathology
  • Vascular anomalies and interventions
  • Cardiac and Coronary Surgery Techniques
  • Cardiac Arrhythmias and Treatments
  • Respiratory Support and Mechanisms
  • Pulmonary Hypertension Research and Treatments
  • Shoulder Injury and Treatment
  • Plant tissue culture and regeneration

Pusan National University Yangsan Hospital
2016-2025

Pusan National University
2007-2024

Pusan National University Hospital
2015-2024

Busan National University of Education
2017-2024

Inje University Busan Paik Hospital
2024

Severance Hospital
2022-2023

Yonsei University
2005-2023

Korea University
2008-2021

Seokyeong University
2020

Seoul National University
2004-2019

10.1038/ng.981 article EN Nature Genetics 2011-11-13

Bioprinting is a technology for constructing bioartificial tissue or organs of complex three-dimensional (3-D) structure with high-precision spatial shape forming ability in larger scale than conventional engineering methods and simultaneous multiple components composition ability. It utilizes computer-controlled 3-D printer mechanism solid free-form fabrication technologies. In this study, sodium alginate hydrogel that can be utilized large-dimension its fast gelation property was studied...

10.1111/j.1525-1594.2011.01377.x article EN Artificial Organs 2011-11-01

Changes in cold hardiness, carbohydrate content and β-amylase gene expression were monitored the shoots of highbush blueberry (Vaccinium corymbosum L.) cultivars 'Sharpblue' 'Jersey' during acclimation (CA) deacclimation (DA). The seasonal patterns similar both cultivars, but levels hardiness determined by electrolyte leakage analysis significantly different; was hardier than 'Sharpblue'. Cold closely related to total soluble sugar (r = −0.98** −0.99** for 'Jersey', respectively). In more...

10.1093/treephys/tps102 article EN Tree Physiology 2012-11-06

Midazolam has been widely studied for preventing emergence agitation. The authors previously reported that in children with sevoflurane anesthesia, intravenous administration of midazolam (0.05 mg/kg) before the end surgery reduced incidence agitation but prolonged time. This study was designed to test hypothesis a lower dose could suppress minimal disturbance time anesthesia.In this randomized, double-blind, placebo-controlled trial, 90 (1 13 yr age) having strabismus were randomized 1:1:1...

10.1097/aln.0000000000000181 article EN Anesthesiology 2014-02-24

Protoporphyrinogen oxidase (Protox), the penultimate step enzyme of branch point for biosynthetic pathway Chi and hemes, is target site action diphenyl ether (DPE) herbicides. However, Bacillus subtilis Protox known to be resistant In order develop herbicide-resistant plants, transgenic rice plants were generated via expression B. gene under ubiquitin promoter targeted cytoplasm or plastid using Agrobacterium-mediated transformation. The integration transgene investigated at T0 generation by...

10.1093/pcp/41.6.743 article EN Plant and Cell Physiology 2000-06-01

Background Currently, no ideal prosthesis is available for right ventricular outflow tract (RVOT) reconstruction in neonates and young infants. Therefore, we developed a 10-mm handmade monocusp expanded polytetrafluoroethylene (ePTFE) valved conduit report our experience. Methods A retrospective clinical review was conducted on 11 consecutive patients who underwent RVOT with ePTFE since May 2018. Six definitive Rastelli operation, five palliative ventricle-to-pulmonary artery formation. The...

10.1177/21501351241306043 article EN World Journal for Pediatric and Congenital Heart Surgery 2025-03-17

Diurnal changes of photosynthesis in the leaves grapevine (Vitis vinifera × V. labrusca) cultivars Campbell Early and Kyoho grown field were compared with respect to gas exchanges actual quantum yield photosystem 2 (ΦPS2) late May. Net photosynthetic rate (PN) two rapidly increased morning, saturated at photon flux density (PPFD) from 1200 1500 µmol m-2 s-1 between 10:00 12:00 slowly decreased after midday. Maximum PN was 13.7 12.5 Kyoho, respectively. The stomatal conductance (gs)...

10.1007/s10535-009-0019-x article EN Biologia Plantarum 2009-03-01

This study was undertaken to assess the early and long-term results of total repair tetralogy Fallot (TOF) identify risk factors associated with late right ventricular (RV) dilatation.The medical records 326 patients (male:female = 192:134) who underwent TOF at Pusan National Dong-A University Hospitals between July 1991 May 2011 were retrospectively reviewed. Median age weight time operation 13.0 months 8.7 kg, respectively. Right end-diastolic dimensions left obtained during follow-up...

10.1093/icvts/ivt361 article EN Interactive Cardiovascular and Thoracic Surgery 2013-08-15

Recent studies have revealed that microglial hyperactivation and neuroinflammation are implicated in development progression of neurodegenerative diseases. In this study, we examined the beneficial effects 3,3′-diindolylmethane (DIM) indole-3-carbinol (I3C), dietary components found cruciferous vegetables, on brain inflammation. DIM, a major metabolite I3C, suppressed lipopolysaccharide (LPS)–induced expression inducible nitric oxide synthase cyclooxygenase-2 BV-2 microglia, but I3C did not....

10.1093/toxsci/kft240 article EN Toxicological Sciences 2013-10-26

We investigated temperature-dependent optical conductivity spectra of a ${\mathrm{Nd}}_{0.7}{\mathrm{Sr}}_{0.3}{\mathrm{MnO}}_{3}$ single crystal. found that polishing and surface scattering effects on the crystal surfaces could significantly distort responses, especially in mid-infrared region. However, oxygen annealing gold normalization processes seemed to remedy distortions. spectral weight metallic state might be composed Drude carrier term strong incoherent absorptions. The temperature...

10.1103/physrevb.60.5251 article EN Physical review. B, Condensed matter 1999-08-15

We report the low temperature current-voltage (I-V) characteristics studies in quasi-one-dimensional conducting polymer nanofibers. find a threshold voltage ${V}_{t}$ below which little current flows at temperatures $30--40\phantom{\rule{0.3em}{0ex}}\mathrm{K}$. For $V>{V}_{t}$ scales as ${(V∕{V}_{t}\ensuremath{-}1)}^{\ensuremath{\zeta}}$ where $\ensuremath{\zeta}\ensuremath{\sim}1.8--2.1$ high biases. Differential conductance oscillations are observed whose magnitude increases decreases...

10.1103/physrevb.72.153202 article EN Physical Review B 2005-10-11

Conjugated linoleic acid (CLA) has been reported to inhibit mouse skin carcinogenesis, particularly in the promotion stage, but underlying molecular mechanisms remain poorly understood. Since persistent induction of cyclooxygenase-2 (COX-2) is frequently implicated we investigated effect cis -9, trans -11-CLA (9Z,11E-CLA) on tumor promoter-induced COX-2 expression HR-1 hairless vivo . Topical application 9Z,11E-CLA caused significant inhibition at 6 h induced by 10 nmol 12- O...

10.1093/carcin/bgl151 article EN Carcinogenesis 2006-07-08

The aims of this study were to document our single-center experience with pediatric acute fulminant myocarditis (AFM) and investigate its clinical features short-term outcomes.We performed a retrospective chart review all children <18 years old who diagnosed AFM between October 2008 February 2013. Data about patient demographics, initial symptoms, investigation results, management, outcomes survivors nonsurvivors collected.Seventeen 21 patients (80.9%) AFM. Eleven (64.7%) survived discharge,...

10.3345/kjp.2014.57.11.489 article EN cc-by-nc-nd Korean Journal of Pediatrics 2014-01-01

Background Dexmedetomidine is an α2-adrenoreceptor agonist with sedative, analgesic and anxiolytic effects, it has more selective α2-adrenergic effect than clonidine. We evaluate the of preansethetic dexmedetomidine 1 µg/kg single infusion on sedation, hemodynamics, anesthetic consumption, recovery profiles during anesthesia. Methods Forty-two female patients American Society Anesthesiologists physical status I or II undergoing gynecologic surgery anticipated operation time 2 h, were...

10.4097/kjae.2013.65.2.114 article EN cc-by-nc Korean journal of anesthesiology 2013-01-01

Kawasaki disease (KD) is an acute systemic vasculitis that can potentially cause coronary artery aneurysms in some children. KD occurs approximately 1.5 times more frequently males than females. To identify sex-specific genetic variants are involved pathogenesis children, we performed a sex-stratified genome-wide association study (GWAS), using the Illumina HumanOmni1-Quad BeadChip data (249 cases and 1,000 controls) replication for 34 candidate SNPs independent sample set (671 3,553...

10.1371/journal.pone.0184248 article EN cc-by PLoS ONE 2017-09-08

As syndromic short stature and overgrowth are heterogeneous the list of causative genes is rapidly expanding, there an unmet need for identifying genetic causes based on conventional gene testing or karyotyping. Early diagnosis leads to proper management patient providing counseling family members at risk in a timely manner.We conducted targeted exome sequencing identify undiagnosed 15 pediatric patients from 13 families Korea. We applied using Next Seq platform TruSight One panel.Among...

10.1111/cge.13038 article EN Clinical Genetics 2017-04-20

We examined the effects of 3 months intensive education (IE) after hospital discharge compared to conventional (CE) on nutritional status and quality diet life among South Korean gastrectomy patients.The study was conducted 53 hospitalized in-patients (IE group, n = 28; CE 25) at Kyung Hee University Hospital Gangdong. Baseline data were collected from electronic medical records additional information gathered via anthropometric measurements, assessment through a patient-generated,...

10.4174/astr.2016.90.2.79 article EN Annals of Surgical Treatment and Research 2016-01-01

Hypothesis: Anorexia and cancer cachexia produce significant loss of adipose tissue muscle mass eventually reduce survival in patients. Study design: This phase II study was conducted to assess the efficacy safety an herbal decoction with Astragali Radix patients anorexia advanced cancer. Methods: All histologic evidence incurable malignancy had a weight at least 5% during preceding 6 months patient-estimated severe anorexia.The administered 30 minutes after meals, three times day for 3...

10.1177/1534735409359180 article EN cc-by-nc Integrative Cancer Therapies 2010-02-11
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