- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Cardiovascular Issues in Pregnancy
- Microbial infections and disease research
- Cardiac Structural Anomalies and Repair
- Influenza Virus Research Studies
- Streptococcal Infections and Treatments
- Mechanical Circulatory Support Devices
- Vasculitis and related conditions
- Immunodeficiency and Autoimmune Disorders
- Autoimmune and Inflammatory Disorders Research
- Pediatric Urology and Nephrology Studies
- COVID-19 Clinical Research Studies
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Urinary Tract Infections Management
- SARS-CoV-2 and COVID-19 Research
- Inflammasome and immune disorders
- Respiratory Support and Mechanisms
- Blood Coagulation and Thrombosis Mechanisms
- Renal Diseases and Glomerulopathies
- Platelet Disorders and Treatments
Catholic University of Korea
2015-2024
Daejeon St. Mary's Hospital
2014-2024
University of Washington
2024
Seoul St. Mary's Hospital
2015-2023
Korea University
2015-2023
Sejong University
2023
Walsh University
2022
Georgetown University
2022
National Research Foundation of Korea
2021
Creative Commons
2021
To reveal the recent epidemiologic features of Kawasaki disease (KD) in South Korea based on data from a nationwide survey.We collected between 2012 and 2014 regarding incidence, symptoms signs, treatment trends coronary complications associated with acute KD by sending questionnaires to 97 hospitals pediatric residency programs as well 19 community without training.We received full partial 13 hospitals, respectively (response rate: 94.8%). A total 14,916 cases were reported these 110 (4588...
Mycoplasma pneumoniae (MP), the smallest self-replicating biological system, is a common cause of upper and lower respiratory tract infections, leading to wide range pulmonary extra-pulmonary manifestations. MP pneumonia has been reported in 10 40% cases community-acquired shows an even higher proportion during epidemics. infection endemic larger communities world with cyclic epidemics every 3 7 years. In Korea, 4-year cycles have observed from mid-1980s present. Although variety serologic...
PURPOSE: To investigate the value of contrast material-enhanced power Doppler ultrasonography (US) in demonstration and characterization tumor vascularity hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Twenty patients with HCC were prospectively evaluated US before after injection agent SH U 508 A. The grade pattern at analyzed, along degree staining angiography. RESULTS: Intra- peritumoral flow signals detected 19 HCCs (95%) unenhanced US. After agent, increased lesions (95%). At...
Abstract Mycoplasma pneumoniae pneumonia (MP) is responsible for 10–40% of cases pediatric community‐acquired pneumonia. Occasionally, progression to severe occurs despite appropriate antibiotic therapy. We retrospectively evaluated the effect prednisolone in 15 children with MP whose clinical and radiographic course worsened broad‐spectrum antibiotics, including macrolides. The mean ( ± SD) age was 6.1 1.9 years, 10 were boys. All had received macrolides at presentation, but they persistent...
Abstract Background M. pneumoniae pneumonia (MP) has been reported in 10-40% of community-acquired cases. We aimed to evaluate the difference clinical features children with MP, according their age and chest radiographic patterns. Methods The diagnosis MP was made by examinations at both admission discharge two serologic tests: indirect microparticle agglutinin assay (≥1:40) cold agglutinins titer (≥1:32). A total 191 were grouped age: ≤2 years (29 patients), 3-5 (81 ≥6 patients). They also...
Antibiotics' effect on Mycoplasma pneumoniae (MP) infection still remains controversial. A prospective study of 257 children with MP pneumonia during a recent epidemic (2015-2016) was conducted. All patients were treated corticosteroids within 24-36 h after admission. Initially, oral prednisolone (1 mg/kg) or intravenous methylprednisolone (IVMP; 1-2 administered for mild patients, and IVMP (5-10 mg/kg/day) severe patients. If showed persistent fever 36-48 disease progression, additive (5...
Colorectal adenocarcinoma, the most common tumor that metastasizes to ovary, is often difficult distinguish from primary ovarian mucinous adenocarcinoma (POMA). Obtaining correct diagnosis but crucial treatment and prognosis.We evaluated immunohistochemical (IHC) expression of cytokeratin 7 (CK7), 20 (CK20), CDX2, CEA, MUC2, MUC5AC alpha-methylacyl-CoA racemase (AMACR) in 22 POMAs 41 metastatic colorectal adenocarcinomas (MCAOs) involving ovaries.MCAOs, contrast with POMAs, were almost...
Prevalence of Primary Immunodeficiency in KoreaThis study represents the first epidemiological based on national registry primary immunodeficiencies (PID) Korea.Patient data were collected from 23 major hospitals.A total 152 patients with PID (under 19 yr age), who observed 2001 to 2005, have been entered this registry.The period prevalence Korea 2005 is 11.25 per million children.The following frequencies found: antibody deficiencies, 53.3% (n = 81), phagocytic disorders, 28.9% 44);...
Mycoplasma pneumoniae (MP) pneumonia epidemics have occurred in 3- to 4-year cycles Korea. We evaluated the epidemiologic characteristics of MP Daejeon, Korea, from 2003 2012.We retrospectively analyzed 779 medical records children (0-15 years old) with admitted our institution and compared data 3 recent epidemics.In patients, mean age male-to-female ratio were 5.0±2.2 1:1, most cases observed autumn. There three during study period, 2003, 2006-2007, 2011. In comparison epidemics, we found...
Mesenchymal stem cells (MSCs) possess immunomodulatory activities, including suppression of T- and B-cell activation. However, their effects on atopic dermatitis (AD) have not yet been studied. Using an ovalbumin-induced AD mouse model, we investigated whether MSCs can be used as therapeutics in AD. We isolated both allogeneic syngeneic clonal (cMSCs) from bone marrow according to the subfractionation culturing method. Our cMSCs suppressed T-cell proliferation cytokine production, interferon...
The novel coronavirus disease 2019 (COVID-19) is spreading globally. Although its etiologic agent discovered as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), there are many unsolved issues in COVID-19 and other infectious diseases. causes of different clinical phenotypes incubation periods among individuals, species specificity, cytokine storm with lymphopenia well the mechanism damage to organ cells unknown. It has been suggested that viral pneumonia, virus itself not a...
We reviewed 12 patients who had Kikuchi-Fujimoto disease (KFD) and presented with prolonged fever lymphadenopathy. The clinical laboratory aspects of the confirmed by excisional lymph node biopsy were analyzed. mean age children was 11.0 +/- 3.0 years (range: 6-15 years). male-to-female ratio 1.4:1. median duration before admission total 13 days 7-65 days) 19.5 9-75 days), respectively. One patient supraclavicular lymphadenopathy, 10 cervical involvement, 1 axillary All histologic findings...
Background: Mycoplasma pneumoniae (MP) pneumonia is a self-limiting disease, but some patients complain of progressive pneumonia, despite appropriate antibiotic treatment.We aimed to introduce the role immune-modulators (corticosteroid and/or intravenous immunoglobulin, IVIG) treatment for childhood MP based on previous our experiences.Materials and Methods: A retrospective case series analysis 183 children with was performed.MP were diagnosed by two Immunoglobulin M (IgM) tests:...