A5041850713- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Molecular Biology Techniques and Applications
- Mechanical Circulatory Support Devices
- Autoimmune and Inflammatory Disorders Research
- Hormonal Regulation and Hypertension
- Birth, Development, and Health
- Forensic and Genetic Research
- Blood Coagulation and Thrombosis Mechanisms
- Vasculitis and related conditions
- Pulmonary Hypertension Research and Treatments
- Inflammasome and immune disorders
- Cardiomyopathy and Myosin Studies
- Renal function and acid-base balance
- Streptococcal Infections and Treatments
- Central Venous Catheters and Hemodialysis
- Blood Pressure and Hypertension Studies
- Cardiovascular Conditions and Treatments
- Cardiovascular and Diving-Related Complications
- Vascular anomalies and interventions
- Clusterin in disease pathology
- Animal Genetics and Reproduction
Korea University Medical Center
2014-2024
Korea University
2011-2024
Ansan University
2018-2024
Seoul National University
2023
University of Ulsan
2008-2018
Asan Medical Center
2008-2018
Chung-Ang University Hospital
2018
Kyung Hee University Hospital at Gangdong
2018
Catholic University of Korea
2018
Ulsan College
2008
To evaluate the short- and mid-term results complications ensuing transcatheter closure of patent ductus arteriosus (PDA). Between October 1999 December 2005, 117 patients (34 males 83 females) underwent attempted percutaneous PDA with a minimum diameter more than 3 mm. Follow-up evaluations were conducted at 1 day 1, 3, 6, 12 months after performance closure. The median age catheterization was 11 yr (range, 0.6 to 68 yr), weight 30 kg 6 74 kg), 4 mm 8 mm). This procedure successfully in 114...
Kawasaki disease (KD) is an acute systemic vasculitis that can potentially cause coronary artery aneurysms in some children. KD occurs approximately 1.5 times more frequently males than females. To identify sex-specific genetic variants are involved pathogenesis children, we performed a sex-stratified genome-wide association study (GWAS), using the Illumina HumanOmni1-Quad BeadChip data (249 cases and 1,000 controls) replication for 34 candidate SNPs independent sample set (671 3,553...
Short tandem repeat (STR) analysis is increasingly being used in forensic case because of the large number STR loci human genome and their highly polymorphic nature. An automated DNA sequencer using high sensitivity infrared (IR) fluorescence technology was to detect allele patterns from simulated samples. The amplification strategy a 19 base pair extension on 5' end one PCR primers. This sequence identical universal M13 Forward sequencing primer which included reaction. Allelic bands were...
We compared tyrosinase cDNA sequences from a line of autosomal albino and Black Silky chickens isolated cultured melanocytes by reverse transcription-polymerase chain reaction (RT-PCR). Both sources produce single DNA fragment predicted normal size. Direct sequencing the PCR product showed three mutated sites in gene chicken. Two silent point mutations deletion six nucleotides (-ΔGACTGG) at 817 bp sequence were observed when with White Leghorn sequences. The deduced chicken protein lacks two...
We defined laboratory marker profiles typical of incomplete Kawasaki disease (iKD) during illness, especially with respect to the presence a coronary artery abnormality such as dilation or aneurysm.This retrospective study examined clinical and markers patients iKD over time, along those complete KD (cKD) febrile controls.Of 795 patients, 178 had iKD, 504 cKD 113 were controls. During transition from acute subacute phase, age-adjusted hemoglobin levels platelet counts significantly lower...
ObjectiveWe evaluated the results of imatinib dose escalation in patients with advanced gastrointestinal stromal tumors (GISTs) after disease progression on standard-dose imatinib.
Abstract Growing evidence indicates that aldosterone is a potent mitogenic signal regulating genes involved in antiapoptosis, cell proliferation and growth. We investigated the role of endogenous renal development, apoptosis, mitogen‐activated protein kinase (MAPK) family expression. Newborn rats were treated with either spironolactone (200 mg/kg/d) olive oil or only for 7 days. TUNEL assay proliferating nuclear antigen (PCNA) stain performed on kidney sections. Immunoblots,...
BACKGROUND AND OBJECTIVES Kawasaki disease (KD) is an acute systemic vasculitis that affects the coronary arteries. Abnormal immune reactions are thought to contribute pathogenesis. The effect of immunoglobulin (Ig) isotype (IgG, IgA, IgM, and IgE) on inflammatory data clinical outcomes patients with KD was examined. METHODS Ig levels in 241 were measured during acute, subacute, convalescent, normal phases disease. RESULTS Compared reference values, IgG, IgM significantly higher subacute...
Near-infrared fluorescence provides a nonradioactive method of detection with high sensitivity and low background. An infrared fluorophore has been attached covalently to the nucleotide deoxyadenosine triphosphate (dATP) provide reagent for enzymatic labeling various types DNA molecules facilitating their an automated sequencing analysis system. reaction products can be labeled internally by performing limited polymerization utilizing infrared-labeled dATP (IR-dATP) as sole source adenine...
Background: This study evaluated echocardiographic changes in full-term healthy neonates during early transitional period from postnatal 0-72 hours at 12-hour intervals by echocardiography.Methods: was a prospective, observational, and longitudinal single-center cohort study.Morphometric, functional, systolic, diastolic, tissue Doppler imaging (TDI) parameters (patent ductus arteriosus [PDA], aorta, superior vena cava [SVC], stroke volume [SV], cardiac output [CO], index [CI], diastolic flow...