- Dysphagia Assessment and Management
- Dental Health and Care Utilization
- Nutrition and Health in Aging
- Balance, Gait, and Falls Prevention
- Craniofacial Disorders and Treatments
- Kawasaki Disease and Coronary Complications
- Cerebral Palsy and Movement Disorders
- Health disparities and outcomes
- Orthodontics and Dentofacial Orthopedics
- Coronary Artery Anomalies
- Cleft Lip and Palate Research
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Musculoskeletal pain and rehabilitation
- Ergonomics and Musculoskeletal Disorders
- Oral microbiology and periodontitis research
- Aging and Gerontology Research
- Dementia and Cognitive Impairment Research
- Stroke Rehabilitation and Recovery
- Psychological Well-being and Life Satisfaction
- Elbow and Forearm Trauma Treatment
- Esophageal and GI Pathology
- Temporomandibular Joint Disorders
- Diet and metabolism studies
- Salivary Gland Disorders and Functions
Tokyo Metropolitan Institute of Gerontology
2013-2025
Sony Computer Science Laboratories
2025
Waseda University
2025
Tokyo Women's Medical University
2025
Tokyo Medical and Dental University
2014-2024
Showa University
1994-2024
The University of Tokyo
2014-2024
Kitano Hospital
2022
Kureha (Japan)
2021
Wakayama Medical University
2015-2020
To identify factors associated with relapse after maxillary advancement in cleft lip and palate patient.Seventy-one patients underwent Le Fort I osteotomy between 1988 1998, 58 (42 unilateral 16 bilateral cleft) complete data were investigated for by clinical cephalometric analysis. The follow-up period ranged from 1.5 to 8.5 years (mean 2.5 years).Horizontal averaged 6.9 mm. There was a significant correlation surgical movement postoperative both the horizontal vertical planes. In...
We launched the Wako Cohort Study in 2023 to identify individual and socio-environmental factors related extension of healthy life expectancy reduction health disparities among community-dwelling adults develop promotion care prevention strategies. This study profile aims describe design participants' at baseline. The is a prospective aged ≥ 40 years living City, Saitama Prefecture, Japan. consists two surveys: mail-in survey for persons face-to-face assessment (on-site survey) those 65...
<ns3:p>Background With the rapid aging of population, increasing life satisfaction among older adults is essential. Negative perceptions are internalized, leading to poor mental health. This study hypothesized that participants with more negative would have lower satisfaction. Methods A cross-sectional survey was conducted across five wards and four cities in Tokyo, Japan. Participants responded questions regarding demographics, satisfaction, adults. Data from 285 (264 women,...
<ns3:p>Background With the rapid aging of population, increasing life satisfaction among older adults is essential. Negative perceptions are internalized, leading to poor mental health. This study hypothesized that participants with more negative would have lower satisfaction. Methods A cross-sectional survey was conducted across five wards and four cities in Tokyo, Japan. Participants responded questions regarding demographics, satisfaction, adults. Data from 285 (264 women,...
Abstract Adequate oral status and functional assessments are important for dysphagia rehabilitation in acute care inpatient settings, especially to establish individualised intake. However, the association between food intake levels function has not been elucidated inpatients. This cross‐sectional study clarified status/function of patients with admitted settings. Admitted aged ≥40 years (n = 459; men: 288; mean age: 70.8 ± 12.0) examined at Department Dysphagia Rehabilitation Iwate Medical...
The objective of this study was to investigate the relationship between normalized regional cerebral metabolic rates glucose (normalized-rCMRglc) and gait function in physically mentally high-functioning older women. One hundred eighty-two community-dwelling women (mean age [SD], 69.4 [6.6] years) without disability instrumental activities daily living mobility limitations underwent positron emission tomography with 18F-fluorodeoxyglucose at rest assess brain activity associated function. We...
Kawasaki disease (KD) is an acute systemic vasculitis that can potentially cause coronary artery aneurysms in some children. KD occurs approximately 1.5 times more frequently males than females. To identify sex-specific genetic variants are involved pathogenesis children, we performed a sex-stratified genome-wide association study (GWAS), using the Illumina HumanOmni1-Quad BeadChip data (249 cases and 1,000 controls) replication for 34 candidate SNPs independent sample set (671 3,553...
Understanding of the underlying mechanisms Fear Falling (FoF) could help to expand potential treatments. Given nature motor performance, decline in planning stage execution may be associated with an expression FoF. The aim this study was assess planning/prediction accuracy people FoF using gait-related imagery (MI). Cross-sectional case/control study. Three health centers Japan. Two hundred and eighty-three community-dwelling older adults were recruited stratified by presence as group...
Patients with terminal cancer undergoing multidisciplinary palliative care often have oral health problems, but these details are still unclear. This cross-sectional study aimed to elucidate the of patients terminal-stage who inpatient recipients acute-phase care, and unveil factors affecting their health.Participants were 121 (68 males, 53 females, mean age: 73.6 ± 11.1 years) complaints. They received at Tokyo Medical Dental University Hospital between April 2017 August 2019. Their...
Apert syndrome is an autosomal dominantly inherited disorder caused by missense mutations in fibroblast growth factor receptor 2 (FGFR2). Surgical procedures are frequently required to reduce morphological and functional defects patients with syndrome; therefore, the development of noninvasive treat critical. Here we aimed clarify etiological mechanisms craniosynostosis mouse models verify effects purified soluble FGFR2 harboring S252W mutation (sFGFR2IIIcS252W) on calvarial sutures mice...
Kawasaki disease (KD) is an acute, self-limited vasculitis of unknown aetiology that predominantly affects infants and young children. We hypothesise cyclosporin A (CsA) may be effective in treating KD by regulating the Ca(2+)/NFAT signalling pathway. This trial compares current standard therapy intravenous immunoglobulin (IVIG) combined IVIG+CsA paediatric patients with severe KD.This a phase III, multicentre, randomised, open-label, blinded-end point evaluates efficacy safety therapy....
Satoh, Kaneshige M.D.; Suzuki, Hiroyuki Matsuzaki, Shohichi D.D.S. Author Information
Apert syndrome is characterized by craniosynostosis and syndactyly, predominantly caused mutation of either S252W or P253W in the fibroblast growth factor receptor (FGFR) 2 gene. In this study, we effects one mutations (S252W) using primary calvarial osteoblasts derived from transgenic mice, Ap-Tg sAp-Tg, that expressed an Apert-type mutant FGFR2 (FGFR2IIIc-S252W; FGFR2IIIc-Ap), soluble form (extracellular domain only) (sFGFR2IIIc-Ap), respectively. Compared to WT-derived osteoblasts, mouse...
Abstract Objectives This cross‐sectional study aimed to examine the oral health of malnourished acute‐care hospital inpatients, who were subjects a nutritional support team (NST). We also elucidate systemic and factors associated with those patients. Background Interventions by NST are essential for inpatient nutrition management require active participation dental professionals. However, information is limited regarding state among acute‐stage inpatients. Materials Methods enrolled 255...
Individuals who are edentulous have a lower intake of fruit, vegetables, fiber, and protein compared with their dentate counterparts because tooth loss is accompanied by decrease in ability to chew. Whether or not combination prosthetic rehabilitation simple dietary advice produces improvement among persons unclear. We aim investigate the effect simultaneous delivered dentists provision new complete dentures on individuals request dentures. Through double-blinded, parallel, randomized...
Abstract Background Dementia is an important health issue for older people and requires early intervention in the mild cognitive impairment (MCI) stage to manage risk factors. Both dynapenia (DP) abdominal obesity (AO) are associated with inflammation oxidative stress, which may be involved pathogenesis of impairment. Therefore, this cross-sectional study, we aimed evaluate association between MCI dynapenic (DAO), a combination DP AO. Methods A total 417 outpatients cardiometabolic diseases...