A5090207660- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Streptococcal Infections and Treatments
- Mechanical Circulatory Support Devices
- Inflammasome and immune disorders
- Blood Coagulation and Thrombosis Mechanisms
- Vasculitis and related conditions
- Autoimmune and Inflammatory Disorders Research
- Pericarditis and Cardiac Tamponade
- Congenital Heart Disease Studies
- Estrogen and related hormone effects
- Cardiovascular Syncope and Autonomic Disorders
- Birth, Development, and Health
- Cardiac Arrhythmias and Treatments
- Connective tissue disorders research
- Circular RNAs in diseases
- Cardiac Ischemia and Reperfusion
- IgG4-Related and Inflammatory Diseases
- Pneumonia and Respiratory Infections
- Atrial Fibrillation Management and Outcomes
- Thyroid Disorders and Treatments
- Bacterial Infections and Vaccines
- Testicular diseases and treatments
Kyung Hee University Hospital at Gangdong
2014-2024
Kyung Hee University
2010-2020
University of Ulsan
2002-2018
Asan Medical Center
2002-2018
Chung-Ang University Hospital
2018
Catholic University of Korea
2018
Kyung Hee University East-West Neo Medical Center
2009-2011
Ulsan College
2002
To reveal the recent epidemiologic features of Kawasaki disease (KD) in South Korea based on data from a nationwide survey.We collected between 2012 and 2014 regarding incidence, symptoms signs, treatment trends coronary complications associated with acute KD by sending questionnaires to 97 hospitals pediatric residency programs as well 19 community without training.We received full partial 13 hospitals, respectively (response rate: 94.8%). A total 14,916 cases were reported these 110 (4588...
Background: This study aimed to investigate recent epidemiologic features of Kawasaki disease (KD) in South Korea. Methods: The ninth triennial nationwide questionnaire survey collected data on the demographic findings, symptoms and signs, treatment patterns coronary artery complications acute-phase KD occurred 2015–2017 from 98 hospitals with pediatric residency programs 108 community without programs. Results: We received 93 (response rate: 94.9%) 75 community-based children’s 69.4%) In...
The processus vaginalis within the inguinal canal forms of Nuck, which is a homolog in women. Incomplete obliteration causes indirect hernia or hydrocele very rare condition Here, we report 2 cases Nuck that were diagnosed with ultrasonography both and magnetic resonance imaging 1 case to confirm sonographic diagnosis. High ligation hydrocelectomy conducted patients. In patient, 14 months later, occurrence contralateral was suspected, but did not require surgery. other patient had history...
Kawasaki disease (KD) is an acute systemic vasculitis that can potentially cause coronary artery aneurysms in some children. KD occurs approximately 1.5 times more frequently males than females. To identify sex-specific genetic variants are involved pathogenesis children, we performed a sex-stratified genome-wide association study (GWAS), using the Illumina HumanOmni1-Quad BeadChip data (249 cases and 1,000 controls) replication for 34 candidate SNPs independent sample set (671 3,553...
Background and Objectives:This was a multicenter study to evaluate the usefulness of tumor necrosis factor-alpha (TNF-α) blocker infliximab for treatment Korean pediatric patients with refractory Kawasaki disease (KD).Subjects Methods: Data from 16 throughout Korea who were diagnosed KD received collected retrospectively.Results: Complete response therapy cessation fever occurred in 13 patients.C-reactive protein (CRP) concentrations decreased following infusion all 14 whom it measured...
Chest pain is common in children and adolescents a reason for referral to pediatric cardiologists. Although most cases of chest these age groups are benign do not require treatment, timely diagnosis important miss life-threatening diseases requiring prompt treatment. We investigated certain clinical characteristics that may be useful the such critical diseases.Patient medical records between July 2006 September 2013 were retrospectively examined. included 517 patients who presented with...
Background and Objectives:We investigated the status of infliximab use in intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) patients incidence coronary artery aneurysms (CAAs) according to treatment regimens.Methods: Between March 2010 February 2017, 16 hospitals participated this study.A total 102 (32.3±19.9months, 72 males) who received at any time after first IVIG failure were enrolled.Data retrospectively collected using a questionnaire.Results: Subjects divided into two...
Purpose Transforming growth factor beta receptor 2 (TGFBR2) is a tumor suppressor gene that plays role in the differentiation of striated cells and remodeling coronary arteries. Single nucleotide polymorphisms (SNPs) this are associated with Marfan syndrome sudden death patients artery disease. Cardiovascular T cell activation TGFBR2 suggest SNPs related to pathogenesis Kawasaki disease (KD) lesion (CAL). Methods The subjects were 105 KD 500 healthy adults as controls. Mean age group was 32...
BACKGROUND AND OBJECTIVES Kawasaki disease (KD) is an acute systemic vasculitis that affects the coronary arteries. Abnormal immune reactions are thought to contribute pathogenesis. The effect of immunoglobulin (Ig) isotype (IgG, IgA, IgM, and IgE) on inflammatory data clinical outcomes patients with KD was examined. METHODS Ig levels in 241 were measured during acute, subacute, convalescent, normal phases disease. RESULTS Compared reference values, IgG, IgM significantly higher subacute...
Mycoplasma is a common cause of respiratory infections and may require differential diagnosis from Kawasaki disease (KD). In this study, we investigated the frequency clinical manifestations mycoplasma infection in patients with KD. Medical records 375 in-patients admitted for treatment during acute stage KD, were collected, reviewed retrospectively. Of these patients, 152 (40.5%) also tested recent infection. Patients positive results (anti-mycoplasma IgM Ab >1:640 or cold agglutinin >1:64)...
The genetic alterations of vitamin D receptor (VDR) are related with the growth long bone.There were a lot reports regarding an association polymorphisms in VDR promoter many disorders, but not idiopathic short stature (ISS).We investigated them ISS.A total 50 subjects, including 29 ISS patients and 21 healthy controls their heights within normal range was recruited.We selected two single nucleotide (SNPs) from (rs11568820 at Cdx-2 binding site upstream exon 1e rs4516035 -1012 1a) as...
Background and Objectives: Patients with Kawasaki disease (KD) are clinically heterogeneous because its diagnosis is based solely on clinical observation there no definitive biomarkers.We dissected the heterogeneity of KD patients using KDassociated genetic variants.Methods: We performed a association analysis in several subgroups categorized by characteristics KD-associated variants B lymphoid tyrosine kinase (BLK; rs6993775) Fc gamma receptor II (FCGR2A; rs1801274) large number case...