- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Kawasaki Disease and Coronary Complications
- Cardiovascular Function and Risk Factors
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Respiratory viral infections research
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Conditions and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Influenza Virus Research Studies
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Asthma and respiratory diseases
- Aortic Disease and Treatment Approaches
- Congenital Diaphragmatic Hernia Studies
- Cardiac and Coronary Surgery Techniques
- Cardiomyopathy and Myosin Studies
- Allergic Rhinitis and Sensitization
- Cardiac pacing and defibrillation studies
- Chemotherapy-induced cardiotoxicity and mitigation
Kyungpook National University
2013-2025
Kyungpook National University Hospital
2001-2025
Inje University
2011
Keimyung University
2011
Although many studies have described an increased risk of necrotizing enterocolitis in duct dependent congenital heart diseases, very few investigated its occurrence full-term infants with diseases.To evaluate the characteristics and factors enterocolitis, we performed a retrospective review 355 diseases who received prostaglandin E1 therapy from April 2000 to May 2020.Necrotizing was observed 10 patients (3.0%). Their average gestational age birth weight were 38.2 weeks 2783.5 g,...
Pediatric hypertension (HTN) is a significant, growing health concern worldwide and also in Korea. Diagnosis, evaluation, treatment of HTN Korean children adolescents are uncertain due to limitations using the current international guidelines, since recommendations by American Academy Pediatrics (AAP) European Society Hypertension (ESH) guidelines differ. Furthermore, these for Western youth, who racially ethnically different from Koreans. In addition, reference blood pressure values all...
We investigated serum cytokine levels in pediatric patients with pandemic influenza H1N1 2009 virus (H1N1) infection-pneumonia and pneumonia but without infection, examined correlations between clinical/laboratory findings.Fifty-seven cases of infection by were confirmed RT-PCR enrolled. Of these 57 cases, 26 had a severe (group 1), 31 mild 2). Sera from 18 3) used as controls. The 10 cytokines determined multiplex assay.The IFN-α, IL-6, IP-10 significantly higher infected than group 3, IL-6...
ABSTRACT Objectives: To assess and compare the long‐term therapeutic response to lamivudine compared with interferon‐α (IFN‐α) in children chronic hepatitis B. Methods: A total of 40 (27 male; age, 1.3–18 y, mean, 7.7 y) B who received for at least 12 months were followed a mean period 39 (24–76) months. Their treatment efficacy was historically that 19 (14 2.1–17 y; 10 had been treated IFN‐α (24–104) Therapeutic responses 2 y after initiation either methods. Results: Two years treatment,...
It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond intravenous immunoglobulin (IVIG) treatment. In this study, we aimed identify useful predictors therapeutic failure in KD.We examined 309 diagnosed KD at the Kyungpook National University Hospital and Inje Busan Paik between January 2005 June 2011. We retrospectively reviewed their medical records analyzed multiple parameters responders nonresponders IVIG.Among children, 30 (9.7%) did IVIG. They had...
Kawasaki disease is an acute systemic vasculitis of which pathogenesis suspected caused by immune dysregulation. The goal this study to evaluate the activation pattern T helper cell type 1 (Th1) and 2 (Th2) in patients with disease. Prospective 60 (male 36, female 24) diagnosis were enrolled. One hundred eighty blood samples from these collected according different clinical stages {before initial intravenous immunoglobulin (IVIG), 5 days after IVIG, months IVIG}. plasma level Th1 cytokines;...
Background and Objectives:We investigated the status of infliximab use in intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) patients incidence coronary artery aneurysms (CAAs) according to treatment regimens.Methods: Between March 2010 February 2017, 16 hospitals participated this study.A total 102 (32.3±19.9months, 72 males) who received at any time after first IVIG failure were enrolled.Data retrospectively collected using a questionnaire.Results: Subjects divided into two...
Acute kidney injury (AKI) is closely associated with the mortality of hospitalized patients and long-term development chronic disease, especially in children. The purpose our study was to assess evidence contrast-induced AKI after cardiac catheterization children heart disease evaluate clinical usefulness candidate biomarkers AKI. A total 26 undergoing due various diseases were selected urine blood samples taken at 0 hr, 6 24 48 hr catheterization. Until catheterization, there no significant...
We evaluated the characteristics of patients with Kawasaki disease (KD) who presented only fever and cervical lymphadenopathy on admission, compared them those typical features but no lymphadenopathy.We enrolled 98 diagnosed KD. Thirteen had day admission (group 1), 31 2), 54 without 3).The mean age (4.3±2.1 years) duration (7.5±3.6 days) before first intravenous immunoglobulin (IVIG) administration were highest in group 1 (P=0.001). Moreover, this showed higher white blood cell neutrophil...
Background and Objectives: The goal of this study was to assess changes in left ventricular (LV) function identify pre-closure factors associated with LV dysfunction {fractional shortening (FS) below 29%} after transcatheter patent ductus arteriosus (PDA) closure. Subjects Methods: Forty-three pediatric patients PDAs underwent cardiac catheterization for hemodynamic studies intervention. Doppler echocardiography performed at pre-closure, post-closure, follow-up. Results: S’ A’ the septum...
Background and Objectives: Anthracyclines are effective drugs that widely used in pediatric cancer treatment.Previous studies have demonstrated exposure to low-dose anthracyclines (<300 mg/m 2 ) induces a progressive decrease cardiac function during long-term follow-up.The goal of this study was assess left ventricular using vector velocity imaging (VVI) children undergoing anthracycline therapy.Subjects Methods: We examined 14 asymptomatic patients who had been treated with normal...
Chronic urticaria (CU) can reduce the quality of life children and their parents, but there are only a few studies on course CU in children. This study aimed to investigate natural identify factors that influence its prognosis.We evaluated 77 diagnosed with CU, who were monitored for at least 48 months. Subjects classified as either chronic spontaneous (CSU) or other clinical features compared. Remission was defined having no symptoms without treatment more than 1 year. The remission rate...
Background: Idiopathic cardiomyopathies (CMPs) are an important heterogeneous group of diseases. With the advance therapeutic strategies, epidemiologic data on CMP have become very important, but only a few been reported in Asian children. We conducted retrospective study primary Korean Methods and Results: Using multicenter survey, we studied among children from January 1998 to December 2006 based classification (2006) by American Heart Association. A total 277 patients were 17...
Purpose Kawasaki disease involves acute febrile systemic vasculitis that can cause a variety of symptoms by affecting various organs. Here, we aimed to evaluate the prevalence, causes, and prognosis sensorineural hearing loss (SNHL) occurring in children with disease. Methods Patients who were diagnosed received inpatient treatment Pediatrics Department at one three university hospitals Daegu city from February 2012 September enrolled study. The clinical features, hematological results,...
The aim of the present study was to evaluate characteristics electrophysiologic studies (EPS) and radiofrequency ablation (RFA) performed in subjects aged less than 30 years with Wolff-Parkinson-White (WPW) syndrome, particularly pediatric patients under 18 age, based on our experience.Two hundred one consecutive WPW syndrome were recruited divided 3 groups according age: group 1, 6 17 years; 2, 29 3, 60 years. clinical, electrophysiological, therapeutic data for these evaluated by a...
This single-center study aimed to assess the clinical features and surgical approaches outcomes of complete transposition great arteries (TGA).TGA patients who had undergone correction at Kyungpook National University Hospital from January 2000 December 2010, were retrospectively evaluated for patient characteristics, manifestation, preoperative management, intraoperative findings, postoperative progress, follow-up status.Twenty-eight (17 boys 11 girls, mean age=10.6±21.5 days) included...
Purpose: Adherence is a major component of successful medical treatment.However, nonadherence remains barrier to effective delivery healthcare worldwide.Methods: Twenty facilities (secondary or tertiary hospitals) belonging the Korean Academy Pediatric Allergy and Respiratory Diseases (KAPARD) participated.Questionnaires were given patients currently receiving treatment in form inhalant useor oral intake transdermal patch for mild moderate asthma.Results: A total 1,838 responded...
목 적 : 선천성 심장병의 개심술 직후에 발생하는 부정맥은 술 후 조기 사망의 주된 원인의 하나인데, 이는 심폐 우회술 및 심근보호법의 발달, 집중치료와 적절한 약물 치료로 감소시킬 수 있다. 이에 이번 연구에서는 조기에 발생한 부정맥의 빈도와 종류, 그 위험 인자들을 조사하여 보았다. 방 법: 2002년 1월부터 2008년 12월까지 심장병으로 경북대학교병원에서 개심술을 시행받은 561명의 환자를 대상으로 하였다. 이들의 의무기록지를 후향적으로 진단명, 수술방법, 수술 부정맥이 시기와 기간, 종류와 치료방법, 부정맥으로 동반된 합병증 사망률, 부정맥 발생 당시 혈액 전해질 수치 등을 분석하였다. 결 과 소아 빈도는 7.3% (42/578 개심술)로 남아 23명, 여아 18명이었으며, 시행 받은 나이는 평균 $8.7{\pm}19.8$ 개월, 몸무게는 $5.8{\pm}4.0kg$ 이었다. 종류는 방실 접합부 이소성 빈맥이 17례로 가장 많았고, 다음으로 가속 심실고유 율동이...
Background: The decision to use transannular patching (TAP) during tetralogy of Fallot (TOF) repair depends on the pulmonary valve annulus size; <i>z</i> score is most commonly used predictor. However, definitive results are not obtained with scores as different data sets for parameters.Purpose: This study aimed identify echocardiographic and other key factors that warranted a change in surgical method TOF surgery.Methods: Sixty-two patients were enrolled divided into (PV)...
목 적: 지속적인 발열과 3개 이하의 가와사끼병 진단 기준을 만족하는 환자군에서 불완전 가와사끼병을 감별하는데 있어 NT-proBNP가 가지는 진단적 의미를 살펴보고자 하였다. 방 법: 2008년 1월부터 2009년 6월까지 가와사끼병으로 및 치료 받은 환자 96명을 대상으로 진단은 입원 당일 열을 포함한 가와사끼병의 고전적인 기준에 따랐고, 기준의 만족 정도에 따라서 완전 환자군과 환자군으로 구분하였으며, NT-proBNP를 혈액검사를 시행하였다. 지속되는 열과 함께 미만의 만족하였지만 임상 경과와 여러 검사들을 통해 19명을 대조군으로 하여 분석하였다. 결 과: 96명의 중 3가지 이하로 만족한 환자는 33명으로 전체 환자의 34% 였다. 양상으로 구강 점막의 변화와 안검 충혈이 가장 많았는데 가와사끼병에 비해 발생 빈도는 적었다(76% vs 98%, 76% 90%). NT-proBNP는 대조군에 유의하게 높았으며( $1407.7{\pm}1633.5pg/mL$...
Acute kidney injury (AKI) is one of the most significant postoperative complications pediatric cardiac surgery. Because serum creatinine has limitations as a diagnostic marker AKI, new biomarkers including neutrophil gelatinase-associated lipocalin (NGAL), molecule-1 (KIM-1), and interleukin-18 (IL-18) are being evaluated to overcome these detect AKI at an early stage after surgery.This study aimed investigate clinical usefulness in young children.Thirty patients with congenital heart...