A5103052007- Respiratory viral infections research
- Tracheal and airway disorders
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Cystic Fibrosis Research Advances
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Bacterial Infections and Vaccines
- Transplantation: Methods and Outcomes
- Pediatric health and respiratory diseases
- COVID-19 Clinical Research Studies
- Otolaryngology and Infectious Diseases
- Neonatal and fetal brain pathology
- Dysphagia Assessment and Management
- Child Nutrition and Water Access
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Studies on Chitinases and Chitosanases
- SARS-CoV-2 and COVID-19 Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Infective Endocarditis Diagnosis and Management
- Voice and Speech Disorders
- Congenital Diaphragmatic Hernia Studies
- ATP Synthase and ATPases Research
Catholic University of Daegu
2011-2024
Daegu Catholic University Medical Center
2019-2023
Seoul National University
2020-2021
Taegu Science University
2016
Dankook University
2011
Chung-Ang University
2000-2003
Mycoplasma pneumoniae is a major causative pathogen of community-acquired pneumonia in children, and the treatment choice macrolides. There an increasing trend reports refractory clinical responses despite macrolide due to emergence macrolide-resistant M. pneumoniae. Early discrimination macrolide-refractory (MrMP) from macrolide-sensitive (MSMP) vital; however, testing for susceptibility at time admission not feasible. This study aimed identify characteristics MrMP Korean comparison with...
Abstract Background Respiratory infections among children, particularly community-acquired pneumonia (CAP), is a major disease with high frequency outpatient and inpatient visits. The causes of CAP vary depending on individual susceptibility, the epidemiological characteristics community, season. We performed this study to establish nationwide surveillance network system identify causative agents for antibiotic resistance in Korean children CAP. Methods monitoring was composed 28 secondary...
Abstract: The present study examined the effects of ambroxol and erdosteine, bronchial expectorants, on cytokine synthesis, granule enzyme release, free radical production in rat alveolar macrophages activated by lipopolysaccharide. Ambroxol erdosteine significantly decreased tumour necrosis factors‐α, interleukin‐1β, interleukin‐6 These drugs reduced superoxide anion, hydrogen peroxide, nitric oxide release acid phosphatase lysozyme lipopolysaccharide‐activated macrophages. showed no...
Abstract Introduction Macrolide‐resistant Mycoplasma pneumoniae (MRMP) has become prevalent in children. This study investigated the clinical and laboratory variables of MRMP macrolide‐sensitive M. (MSMP) identified factors associated with prolonged hospital admission Methods A prospective multicenter was conducted 1063 children <18 years old July 2018–June 2020. The 454 had a positive polymerase chain reaction assay. Results Most subjects (78.4%), all mutated strains A2063G transition....
Transient magnetic resonance (MR) signal changes in the splenium of corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion mild gastroenteritis (CwG) is frequently rotaviral infections. This entity characterized normal laboratory findings, electroencephalogram, neuroimaging,...
The present study examined the effect of ambroxol on toxic action peroxynitrite and respiratory burst in activated phagocytic cells. Ambroxol decreased inactivation or destruction alpha1-antiproteinase induced by (ONOO-) hypochlorous acid (HOCl), which was similar to penicillamine glutathione greater than diclofenac sodium naproxen sodium. significantly ONOO--mediated tyrosine nitration iron plus EDTA-mediated degradation 2-deoxy-D-ribose. attenuated production superoxide, hydrogen peroxide,...
Background: To address the public’s fear of coronavirus disease 2019 (COVID-19), understanding clinical features is essential. However, research on COVID-19, including illness duration and post-acute in Korean pediatric patients has been limited. Therefore, this study investigated COVID-19 based medical records with a history who visited single center. Methods: In total, 311 were included study. The presence 19 symptoms examined. Additionally, by dividing into different age ranges. Patients...
Collet-Sicard syndrome is a rare condition characterized by the unilateral paralysis of 9th through 12th cranial nerves. We describe case 46-year-old man who presented with dysphagia after falling down injury. Computed tomography demonstrated burst fracture atlas. Physical examination revealed decreased gag reflex on left side, laryngeal elevation, tongue deviation to and atrophy trapezius muscle. Videofluoroscopic swallowing study (VFSS) frequent aspirations massive amount thick liquid...
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder that leads to secondary dysfunction. PCD rare disease, and data on it are limited in Korea. This study systematically evaluated the clinical symptoms, diagnostic characteristics, treatment modalities of pediatric Korea.This Korean nationwide, multicenter study, conducted between January 2000 August 2022, reviewed medical records patients diagnosed with PCD. Prospective studies have been added determine whether...
We present the case of a patient with Epstein-Barr virus (EBV) encephalitis who developed abnormal white matter lesions during chronic phases infection. A 2-year-old-boy was admitted for 2 day history decreased activity ataxic gait. The results physical examination were unremarkable except generalized lethargy and enlarged tonsils exudates. Brain magnetic resonance imaging (MRI) at admission showed multiple high signal intensities in both basal ganglia thalami. result EBV polymerase chain...
Background: Bronchial hyperresponsiveness (BHR), an important physiological feature of asthma, is a prognostic marker childhood asthma.Purpose: We aimed to investigate the factors associated with BHR in adolescents asthma.Methods: Two hundred and fifteen (≥13 years age; 149 males, 66 females) who were diagnosed asthma during enrolled, underwent methacholine challenge tests, divided into group (<25 mg/mL provocation concentration causing 20% fall forced expiratory volume 1 second...
Viral load and shedding duration are highly associated with the transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. However, limited studies have reported on viral or in children adolescents infected sudden coronavirus 2 (SARS-CoV-2).This study aimed to investigate natural course asymptomatic mild pediatric cases.Thirty-one (<18 years) confirmed SARS-CoV-2 infection were hospitalized enrolled this study. loads evaluated nasopharyngeal swab samples using...
Purpose: Croup is known to have epidemics in seasonal and biennial trends, be strongly associated with of parainfluenza virus.However, annual croup not been clearly reported Korea.This study aimed examine the seasonal/annual patterns etiologies childhood Korea during a consecutive 6-year period.Methods: Pediatric data were collected from 23 centers 1 January 2010 31 December 2015.Electronic medical records, including multiplex reverse transcription polymerase chain reaction (RT-PCR) results,...
Fractional exhaled nitric oxide (FeNO) is a non-invasive test for evaluating the degree of airway inflammation and diagnosis, evaluation, treatment asthma. We attempted to measure FeNO levels in Korean children with asthma determine its cutoff value diagnosing enrolled 176 adolescents between ages 5 18 years, who visited evaluation chronic cough, shortness breath, wheezing. Among them, 138 patients underwent skin prick tests or inhalation Immuno CAP (UniCAP; Pharmacia, Uppsala, Sweden)...
Introduction: Respiratory infection in particular community acquired pneumonia (CAP) children is a major disease that ranks high outpatient and inpatient cases. The causes of CAP vary depending on the individual susceptibility, epidemiological characteristics community, season. We performed this study to establish nationwide survillance network system identify causative agents for antibiotics resistance Korean with CAP.. Methods: monitoring was composed 28 secondary tertiary medical...
Background: Residential greenness has been reported to be positively associated with children health benefit including improved cognitive functions. We investigated the association between surrounding during pregnancy and at age of 6 years old intelligence quotient(IQ) 6-year-old in Seoul, South Korea. also aimed analyze whether these effects differed by type such as natural or artificial greenness. Method: This study was based on 190 mother-child participants, who have lived Seoul prenatal...