A5045340301- Pneumonia and Respiratory Infections
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Respiratory viral infections research
- Food Allergy and Anaphylaxis Research
- Pediatric health and respiratory diseases
- Bacterial Infections and Vaccines
- Mast cells and histamine
- Obstructive Sleep Apnea Research
- Respiratory and Cough-Related Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Urticaria and Related Conditions
- Tuberculosis Research and Epidemiology
- Dermatology and Skin Diseases
- Microbial infections and disease research
- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Contact Dermatitis and Allergies
- Vitamin D Research Studies
- Sleep and Wakefulness Research
- Antibiotics Pharmacokinetics and Efficacy
- Viral gastroenteritis research and epidemiology
- Obesity, Physical Activity, Diet
- Breastfeeding Practices and Influences
- Chronic Obstructive Pulmonary Disease (COPD) Research
Jangheung Mushroom Industry Research
2021-2025
Kyung Hee University Medical Center
2023
Eulji University
2013-2022
Eulji General Hospital
2009-2022
Eulji University Hospital
2018-2022
Pediatrics and Genetics
2021
Seoul National University Children's Hospital
2018
Seoul National University
1997-2018
Kangwon National University
2018
Seoul National University Bundang Hospital
2018
In Korea, Mycoplasma pneumoniae was detected in 255/2,089 respiratory specimens collected during 2000-2011; 80 isolates carried 23S rRNA gene mutations, and 69/123 culture-positive samples with the mutation were resistant to 5 macrolides. During 2000-2011, prevalence of increased substantially. These findings have critical implications for treatment children mycoplasma pneumonia.
Abstract Background Community–acquired pneumonia (CAP) is one of the leading worldwide causes childhood morbidity and mortality. Its disease burden varies by age etiology time dependent. We aimed to investigate annual seasonal patterns in etiologies pediatric CAP requiring hospitalization. Methods conducted a retrospective study 30,994 children (aged 0–18 years) with between 2010 2015 at 23 nationwide hospitals South Korea. Mycoplasma pneumoniae (MP) was clinically classified as...
Mycoplasma pneumoniae is a major causative pathogen of community-acquired pneumonia in children, and the treatment choice macrolides. There an increasing trend reports refractory clinical responses despite macrolide due to emergence macrolide-resistant M. pneumoniae. Early discrimination macrolide-refractory (MrMP) from macrolide-sensitive (MSMP) vital; however, testing for susceptibility at time admission not feasible. This study aimed identify characteristics MrMP Korean comparison with...
Pollen-food allergy syndrome (PFAS) is an immunoglobulin E (IgE)-mediated in pollinosis patients caused by raw fruits and vegetables the most common food adults. However, there has been no nationwide study on PFAS Korea. In this study, we investigated prevalence clinical characteristics of Korea.Twenty-two investigators participated which with allergic rhinoconjunctivitis and/or bronchial asthma pollen were enrolled. The questionnaires included demographic characteristics, a list vegetables,...
Abstract Background Respiratory infections among children, particularly community-acquired pneumonia (CAP), is a major disease with high frequency outpatient and inpatient visits. The causes of CAP vary depending on individual susceptibility, the epidemiological characteristics community, season. We performed this study to establish nationwide surveillance network system identify causative agents for antibiotic resistance in Korean children CAP. Methods monitoring was composed 28 secondary...
Shellfish and fish are common causes of food allergy (FA) in Asia, with significant prevalence rates reported across various countries. This study aimed to identify the diagnostic decision points (DDPs) for shrimp, crab, cod allergies Korean children. We enrolled participants aged 18 years or younger suspected through a retrospective review medical records from nationwide 14-center between January 2018 March 2022. FA was diagnosed using an open oral challenge reproducible convincing history...
With the emergence of macrolide resistance, concerns about efficacy macrolides for treatment Mycoplasma pneumoniae (MP) pneumonia in children have been raised. This study aimed to determine effect resistance on outcome who were hospitalized with MP pneumonia. Between 2010 and 2015, we performed culture from nasopharyngeal samples obtained at five hospitals Korea. Macrolide was determined by analysis 23S rRNA gene transition minimal inhibitory concentrations four macrolides. Medical records...
Few studies have investigated the incidence of anaphylaxis induced by individual or structurally similar cephalosporins. The aims study were to assess cephalosporin-induced and evaluate clinical efficacy screening skin tests.In this retrospective cohort study, we obtained information on total cephalosporin use in intravenous recipients 12 general hospitals between 2013 2015. Cephalosporins divided into 4 groups according side-chain structures. was assessed for each cephalosporin, generation,...
Breastfeeding reportedly reduces the overall frequency of infections. Respiratory syncytial virus (RSV), most common respiratory pathogen in infants, involves recurrent wheezing and has a pathogenic mechanism related to airway structural damage.This study aimed investigate whether breastfeeding beneficial effect against RSV-induced infection compared formula feeding among infants Korea.We retrospectively reviewed medical records under 1 year age who were admitted with RSV between January...
Obstructive sleep apnea (OSA) in children is a frequent disease for which optimal diagnostic methods are still being defined. Treatment of OSA should include providing space, improving craniofacial growth, resolving all symptoms, and preventing the development adult years. Adenotonsillectomy (T&A) has been treatment choice thought to solve young patient's problem, not case most adults. Recent reports showed success rates that vary from 27.2% 82.9%. Children snoring regularly generally have...
Many studies have reported that pollen-food allergy syndrome (PFAS) can cause anaphylaxis. No comprehensive investigations into anaphylaxis in PFAS been conducted, however. In this study, we investigated the clinical manifestations and risk factors for Korean patients with pollinosis.Data were obtained from a nationwide cross-sectional study previously on pollinosis. Data 273 collected, including demographics, list of culprit fruits vegetables, food allergy. We analyzed 27 compared them...
The purpose of this study was to examine sleep patterns in a large sample infants and toddlers (ages birth 36 months) Korea, compare patterns, problems, ecology, parental behaviors global data on young children both predominately Asian (P-A) Caucasian (P-C) countries/regions.We additionally examined parent child demographic information, behaviors, aspects the ecology as predictors among Korea.Parents/caregivers 1,036 Korean completed an expanded, internet-based version brief infant...
Abstract To investigate the genetic background for emergence of macrolide resistance, we characterized features Mycoplasma pneumoniae using multilocus sequence typing. Of 146 M. strains collected during 5 consecutive outbreaks pneumonia 2000–2016 in South Korea, resistance increased from 0% first outbreak to 84.4% fifth. Among 8 types (STs) identified, ST3 (74.7%) was most prevalent, followed by ST14 (15.1%). Macrolide-susceptible comprised different STs, and all macrolide-resistant were...
To validate the prevalence rate of symptoms asthma produced by phase I ISAAC (International Study Asthma and Allergies in Childhood) study, hypertonic saline challenge test was carried out during II study at a year after study. For six middle schools from three cities were selected. Finally, 499 children who responded to both studies analyzed. All subjects asked complete written questionnaire (WQ) first, followed video (AVQ 3.0) Of children, only 19 (3.8%) positive bronchial test. The degree...
To investigate the frequency of childhood sleep problems at pediatric clinics in Seoul and Gyeonggi provinces.Children (n=936) their parents who visited 5 primary 1 secondary outpatient were invited to complete a Pediatric Sleep Questionnaire.Among patients, 901 (96.3%) answered questionnaires sufficient detail for evaluation. The participant's mean age was 4.35±3.02 years (range, 0-18 years). male female ratio 1:0.93 (466 boys, 435 girls). Habitual snoring (>3 day/week) reported 16.9%...
Abstract Introduction Macrolide‐resistant Mycoplasma pneumoniae (MRMP) has become prevalent in children. This study investigated the clinical and laboratory variables of MRMP macrolide‐sensitive M. (MSMP) identified factors associated with prolonged hospital admission Methods A prospective multicenter was conducted 1063 children <18 years old July 2018–June 2020. The 454 had a positive polymerase chain reaction assay. Results Most subjects (78.4%), all mutated strains A2063G transition....
To evaluate the clinical characteristics of vitamin D deficiency and its association with iron anemia (IDA).A total 171 children aged less than two years underwent 25-hydroxyvitamin D(3) tests between January 2007 July 2009. The study was classified into groups: normal insufficiency, by their levels.In total, 120 were in group (mean age, body weight heights 12.5±7.0, 9.3±0.9 kg 76.8±1.1 cm), 51 insufficiency (9.9±5.4 months, 9.0±0.9 75.1±0.9 cm). Vitamin most commonly diagnosed spring (44%)....
To evaluate whether obstructive sleep apnea (OSA) and its severity are related to dyslipidemia alanine transaminase elevation as a marker of nonalcoholic fatty liver disease in children.The data collected from polysomnography, laboratory measurements (lipid profile enzyme), body mass index children aged 0-18 years who visited the pediatric department between 2012 2018 were retrospectively analyzed.There total 273 participants study (ages 0-6 years, 7-12 13-18 years: 61.9%, 26.4%, 11.7%,...
Background: Asthma is a heterogeneous disease, characterized by chronic airway inflammation. exacerbations (AE) are episodes progressive increase in symptoms of shortness breath, cough, wheezing, or chest tightness with decrease lung function. There have been previous studies that examined the role eosinophil-derived neurotoxin (EDN) asthma, but there no EDN children experiencing AE. Objective: In this study, we aimed to examine association function and prognosis admitted for severe Methods:...
Background: Invasive bacterial infections in apparently immunocompetent children were retrospectively analyzed to figure causative organisms Korea.Methods: A total of 947 cases from 25 university hospitals identified 2006 2010 as a continuance previous 10-year period study 1996 2005.Results: Escherichia coli (41.3%),Streptococcus agalactiae (27.7%), and Staphylococcus aureus (27.1%) the most common pathogens infants < 3 months age.S. was prevalent cause meningitis pneumonia E. major...
This study was performed to measure early changes in the serotype distribution of pneumococci isolated from children with invasive disease during 3-year period following introduction 10- and 13-valent pneumococcal conjugate vaccines (PCVs) Korea. From January 2011 December 2013 at 25 hospitals located throughout Korea, were among who had (IPD). Serotypes determined using Quellung reaction, change analyzed. Seventy-five cases IPD included. Eighty percent patients aged 3-59 months, 32% a...
목 적: 식생활의 서구화와 운동량의 감소로 우리 나라에서 소아 비만은 증가하고 있는 추세이며 비만아에서는 고혈압, 이상 지질 혈증, 비알코올성 지방간 및 당뇨 등의 합병증이 발생할 수 있다. 이에 저자들은 비만의 유병률 비만아에서 동반되는 대사 이상의 유병률을 알아보고 정도에 따른 유병...