Sang Hyuk

ORCID: 0000-0002-0582-9286
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Research Areas
  • Viral gastroenteritis research and epidemiology
  • Bacterial Infections and Vaccines
  • Pneumonia and Respiratory Infections
  • Bacterial Identification and Susceptibility Testing
  • Antimicrobial Resistance in Staphylococcus
  • Respiratory viral infections research
  • Diphtheria, Corynebacterium, and Tetanus
  • Clostridium difficile and Clostridium perfringens research
  • Pediatric health and respiratory diseases
  • Neonatal Respiratory Health Research
  • Hepatitis Viruses Studies and Epidemiology
  • Bacterial biofilms and quorum sensing
  • Pediatric Urology and Nephrology Studies
  • Urinary Tract Infections Management
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Mycobacterium research and diagnosis
  • Peripheral Neuropathies and Disorders
  • Veterinary medicine and infectious diseases
  • Viral Infections and Immunology Research
  • Salmonella and Campylobacter epidemiology
  • Complement system in diseases
  • Infectious Encephalopathies and Encephalitis
  • Historical Medical Research and Treatments
  • Infectious Diseases and Tuberculosis
  • Hepatitis B Virus Studies

Daegu Fatima Hospital
2003-2019

Our Lady of Fatima Hospital
2008

: Pertussis continues to pose a substantial global health challenge despite widespread vaccination programs. This study aimed analyze the epidemiological characteristics of recent pertussis cases in Gyeongnam region South Korea.

10.3390/vaccines12111261 article EN cc-by Vaccines 2024-11-08

We evaluated the immunogenicity and safety of pentavalent human-bovine reassortant rotavirus vaccine in 178 Korean healthy infants. Seroresponse rate for serum antirotavirus IgA titers was 94.7% among 94 recipients, as compared with 13.5% 52 placebo recipients. rates neutralizing antibody to each human serotype were significantly higher group than group. This generally well tolerated immunogenic.

10.1097/inf.0b013e31815aba79 article EN The Pediatric Infectious Disease Journal 2008-02-01

This study was conducted to evaluate age-specific seroprevalence of pertussis in Korea and formulate a strategy prevent reduce the incidence pertussis. Residual serum samples healthy adolescents adults 11 yr age or older were collected between July 2012 December 2012, anti-pertussis toxin (PT) IgG titers measured using commercial ELISA kit. We compared mean anti-PT six groups: 11-20, 21-30, 31-40, 41-50, 51-60, ≥ 61 yr. A total 1,192 subjects enrolled. The titer 35.53 ± 62.91 EU/mL 41.4%,...

10.3346/jkms.2014.29.5.652 article EN cc-by-nc Journal of Korean Medical Science 2014-01-01

Background: Invasive bacterial infections in apparently immunocompetent children were retrospectively analyzed to figure causative organisms Korea.Methods: A total of 947 cases from 25 university hospitals identified 2006 2010 as a continuance previous 10-year period study 1996 2005.Results: Escherichia coli (41.3%),Streptococcus agalactiae (27.7%), and Staphylococcus aureus (27.1%) the most common pathogens infants < 3 months age.S. was prevalent cause meningitis pneumonia E. major...

10.3346/jkms.2018.33.e45 article EN cc-by-nc Journal of Korean Medical Science 2018-01-01

Detection of Rotavirus Genotypes in Korea 5 Years after the Introduction VaccinesRotavirus (RV) is one most important viral etiologic agents acute gastroenteritis (AGE) children.Although effective RV vaccines (RVVs) are now used worldwide, novel genotypes and outbreaks resulting from rare genotype combinations have emerged.This study documented a Korean population children with AGE yr introduction RVV assessed potential differences based on vaccination status or vaccine type.Children less...

10.3346/jkms.2015.30.10.1471 article EN cc-by-nc Journal of Korean Medical Science 2015-01-01

This study was performed to measure early changes in the serotype distribution of pneumococci isolated from children with invasive disease during 3-year period following introduction 10- and 13-valent pneumococcal conjugate vaccines (PCVs) Korea. From January 2011 December 2013 at 25 hospitals located throughout Korea, were among who had (IPD). Serotypes determined using Quellung reaction, change analyzed. Seventy-five cases IPD included. Eighty percent patients aged 3-59 months, 32% a...

10.3346/jkms.2016.31.7.1082 article EN cc-by-nc Journal of Korean Medical Science 2016-01-01

We phylogenetically analyzed the Escherichia coli strains isolated from children with urinary tract infection (UTI) in 2 regions of Korea. Virulence factors (VFs) and antibiotic resistance were also determined to compare possible differences.A total 138 E. collected regions; Gyeongin (78 strains) Gyeongnam (60 strains). The phylogenetic groups using triplex polymerase chain reaction (PCR) method multiplex PCRs used detect 7 VFs genes (fimH, papC, iutA, hlyA, sfa/focDE, afa/draBC, kpsMT II)....

10.3345/kjp.2012.55.11.420 article EN cc-by-nc-nd Korean Journal of Pediatrics 2012-01-01

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher we support invest in the microbiology community, to benefit of everyone. This supports our principal goal develop, expand strengthen networks available members so that they can generate new knowledge about microbes ensure it is shared with other communities.

10.1099/jmm.0.000373 article EN Journal of Medical Microbiology 2016-10-21

목적: 우리나라의 백일해에 대한 연령별 방어면역 상태를 평가하고자 면역혈청학적 연구를 시행하였다. 방법: 국내 4개 대학병원에 방문한 건강한 소아, 청소년 및 성인을 대상으로 하였다. 대상을 연령에 따라 7개 연령군으로 구분하였고 ELISA 방법을 이용하여 백일해의 항체가를 측정하였다. 연령군별 기하 평균항체가와 각 양성 보이는 피험자의 비율을 조사하였다. 제조사의 지침대로, 항체가가 24.0 EU/mL 이상인 경우를 양성으로 판정하였다. 결과: 전체 1,605명의 피험자가 연구에 참여하였고, 평균항체가는 $56.16{\pm}50.54EU/mL$ 였다. 연령군별로는 11세 미만 소아 연령군( $64.78{\pm}53.24EU/mL$ )이 가장 높은 평균항체가를 보였다(P 【Purpose: We conducted the immunoassay of pertussis according to ages, in order evaluate protective immunity against...

10.14776/kjpid.2012.19.2.55 article EN Korean Journal of Pediatric Infectious Diseases 2012-01-01

Purpose:Urinary tract infection(UTI) is one of the most frequent infections in children. E. coli etiological micropathogen pediatric community UTI, and has developed resistance to many antibiotics, highlighting need for regular surveys this organism resistant patterns community. The aim study was determine oral antibiotic susceptibility coli, isolated from patients with uncomplicated acquired UTI. Methods:E. isolates, obtained UTI between October 2004 September 2005. And minimal inhibitory...

10.3345/kjp.2006.49.7.777 article EN cc-by-nc-nd Korean Journal of Pediatrics 2006-01-01

Purpose : This study was undertaken to evaluate the immunogenicity and reactogenicity of Td booster immunization in early preadolescents Korea. Methods Healthy preadolescents, who had been vaccinated with 4 or 5 doses DTaP vaccines until 6 years old age, were enrolled this from August 2006 April 2007. Diphtheria tetanus anti-toxoid antibodies sera measured by ELISA just before vaccination weeks after immunogenicity. Local systemic adverse reactions observed for access reactogenicity. Results...

10.3345/kjp.2008.51.11.1185 article EN cc-by-nc-nd Korean Journal of Pediatrics 2008-01-01

목적: 백일해는 백신접종으로 예방이 가능한 질환이지만 세계적으로 증가하고 있고, 국내에서도 환자 가 있는 추세이다. 저자들은 최근 창원 지역에서 발생한 백일해 환자의 역학적인 특징과 임상 양상을 알아보고자 이 연구를 실시하였다. 방법: 2015년 7월부터 2016년 3월까지 호흡기 증상을 주소로 창원파티마병원 소아청소년과에 내원하는 중 1주 이상의 기침을 하면서 발작적인 기침, 기침 후 구토, 흡기 시 `흡` 소리(whooping), 야 간 기침이 동반된 환자들을 대상으로 검체를 채취하여 백일해에 대한 배양, 중합연쇄반응검사를 실시하였고, 혈액의 항백일해 독소 항체검사(anti-pertussis toxin of ELISA kit, IBL Interna-tional GmbH)를 기저에 질환이 있거나 1년 안에 DTaP 혹은 Tdap 백신 접종을 한 경우에는 제외하였다. 결과: 연구 기간 동안 대상 50명 진단된 환자는 37명이었다. 중합연쇄반응검사에서 양성 인 2명이었고...

10.14776/piv.2017.24.1.37 article KO Pediatric Infection & Vaccine 2017-01-01

목적: 급성 위장관염으로 입원한 소아 환자들의 중증도를 여러 척도로 평가하여 각 척도간의 차이를 비교하고, 원인 바이러스가 밝혀진 예를 따로 분류하여 병원체에 따른 임상양상 및 중증도의 알아보고자 하였다. 방법: 전향적으로 전국 8개 지역 9개 의료기관의 소아청소년과에 진단받아 5세 미만의 환자를 대상으로 Vesikari 척도, Clark 수정 Flores 평가하였다. 연구군으로부터 수집된 분변 검체로 로타바이러스, 장 아데노바이러스는 효소면역법으로, 노로바이러스, 아스트로바이러스, 사포바이러스는 RT-PCR 방법으로 검출하였다. 결과: 최종 연구 대상군은 총 214례로 남녀비는 1.58:1이고, 연령층은 6개월 미만이 35명(16.4%), 6-23개월이 105명(49.1%), 24-59개월이 74명(34.5%)이었다. 척도와 척도간 일치율은 0.521 (P 【Purpose: This study aimed to evaluate the disease severity of...

10.14776/kjpid.2014.21.1.43 article EN Korean Journal of Pediatric Infectious Diseases 2014-01-01

Virus-associated immune thrombocytopenic purpura (ITP) can occur following common viruses, but cases of ITP associated with influenza infection has seldom been reported. In this report we describe a previously healthy 5-year-old boy who admitted fever, flu-like symptoms and few bruises on both legs. Severe thrombocytopenia were found. Bone marrow aspirates biopsy showed no abnormalities results coagulation tests all in normal limit. Real-time polymerase chain reaction was positive for B...

10.14776/piv.2015.22.2.117 article EN Pediatric Infection & Vaccine 2015-01-01

Posterior reversible leukoencephalopathy syndrome is a clinical radiographic of many causative factors. Sudden onset headache, vomiting, altered mental status, blurred vision and seizures are main symptoms shown in posterior syndrome. In addition, it typically shows radiological findings edema the white matter cerebrum, being commonly bilateral but asym­metric. We report case poststreptococcal glomerulonephritis (PSGN) presenting as Immediate control hypertension resulted rapid complete...

10.14776/piv.2015.22.2.113 article EN Pediatric Infection & Vaccine 2015-01-01
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