A5012335710- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Antifungal resistance and susceptibility
- Mycobacterium research and diagnosis
- Antibiotics Pharmacokinetics and Efficacy
- Fungal Infections and Studies
- Enterobacteriaceae and Cronobacter Research
- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Bacterial biofilms and quorum sensing
- Urinary Tract Infections Management
- Infectious Diseases and Mycology
- Escherichia coli research studies
- Neutropenia and Cancer Infections
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Plant Pathogens and Fungal Diseases
- Antibiotic Use and Resistance
- Clostridium difficile and Clostridium perfringens research
- Pneumocystis jirovecii pneumonia detection and treatment
- Clinical Laboratory Practices and Quality Control
- Infections and bacterial resistance
- Infective Endocarditis Diagnosis and Management
- Pharmaceutical and Antibiotic Environmental Impacts
Seoul St. Mary's Hospital
2016-2025
Catholic University of Korea
2016-2025
Massachusetts Institute of Technology
2019
Seoul Institute
2015
Government of the Republic of Korea
2015
St. Paul's Hospital
2015
Catholic University of America
2013
St. Mary’s Hospital
2006
Clinical Research Management
2004
Recently, resistance to extended-spectrum cephalosporins due acquired beta-lactamases has been reported in Pseudomonas aeruginosa. The aim of this study was investigate the prevalence Ambler class A and D their derivatives antimicrobial susceptibilities P. aeruginosa isolated from various parts Korea.A total 252 consecutive, non-duplicate isolates were studied for presence or beta-lactamase. Antibiotic susceptibility tests PCR amplification genes encoding (bla(PSE-1), bla(PER-1), bla(VEB-1),...
Purpose:The increasing prevalence of antimicrobial resistant bacteria has become a serious worldwide problem.The aim this study was to analyze resistance data generated in 2009 by hospitals and commercial laboratories participating the Korean Nationwide Surveillance Antimicrobial Resistance program.Materials Methods: Susceptibility were collected from 24 two laboratories.In analysis, did not include intermediate susceptibility.Duplicate isolates excluded analysis hospital isolates, but...
Stenotrophomonas maltophilia causes serious infections in immunocompromised hosts. Here, we analyzed the clinical characteristics of S. bloodstream infection (BSI) patients with hematologic malignancies and evaluated vitro synergistic effects antimicrobial combinations. We retrospectively reviewed all consecutive episodes BSIs adult from June 2009 to May 2014, susceptibility synergy tests using high-throughput bioluminescence assay performed for available isolates. Among 11,004 admissions...
Jayoung Kim, M.D., Ji Young Lee, Ph.D., Sang Il Wonkeun Song, Jae-Seok Seungwon Jung, Jin Kyung Yu, M.S., Kang Gyun Park, M.T., and Yeon-Joon M.D.. Ann Lab Med 2014;34:20-5. https://doi.org/10.3343/alm.2014.34.1.20
Sojeong Yun, B.S., Ji Hyeong Ryu, M.S., Joo Hee Jang, Hyunjoo Bae, Seung-Hyo Yoo, M.T., Ae-Ran Choi, Sung Jin Jo, M.D., Jihyang Lim, Jehoon Lee, Hyejin Sung-Yeon Cho, Dong-Gun Jongmin Seok Chan Kim, Yeon-Joon Park, Hyeyoung and Eun-Jee Oh, M.D.. Ann Lab Med 2021;41:577-87. https://doi.org/10.3343/alm.2021.41.6.577
In Young Yoo, M.D., Ph.D., Joo An Kwon, M.T., Miran Lee, Seung-Hyun Jung, Jung Ok Kim, M.S., Sung Il Ha, and Yeon-Joon Park, Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2023.0430
Microbial contamination of platelet concentrates (PC) remains a persistent challenge in transfusion medicine, necessitating robust preventive measures prior to product release. Differentially expressed gene (DEG) analysis microbe inoculated PC offers promising approach identifying potential biomarkers for detection. Within PC, each S. aureus (ATCC 29213) and epidermidis 12228) was 103 CFU/mL concentration. Total RNA extracted from the samples at predetermined time points (0-, 1-, 3-, 6-hours...
Understanding the virulence and pathogenicity of invasive nontyphoidal Salmonella (iNTS) in children may support timely treatment enable closer monitoring chronic infections. iNTS epidemiology Asia remains inadequately described. We analyzed genetic diversity genes associated with extra-intestinal invasion Korean children. isolates from <18 yrs age diagnosed moderate-to-severe salmonellosis between January 2019 December 2021 were subjected to antibiotic susceptibility testing whole-genome...
Antimicrobial Susceptibility of Stenotrophomonas maltophilia Isolates from Korea, and the Activity Combinations against IsolatesThe aim this study was to determine antimicrobial susceptibility recent clinical isolates compare activity levels several combinations antimicrobials.A total 206 non-duplicate S. collected in 2010 11 university hospitals.Antimicrobial testing performed using Clinical Laboratory Standards Institute agar dilution method.In vitro tested checkerboard method.The rates...
We evaluated the coincidence rate between Vitek MS system (bioMérieux, France) and 2 in identifying uropathogens directly from urine specimens.Urine specimens submitted to our microbiology laboratory July September 2013 for Gram staining bacterial culture were analyzed. Bacterial identification was performed by using conventional method. Urine showing a single morphotype processed culturing matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Of 2,370...
We evaluated the reliability and accuracy of combined use matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) bacterial identification Vitek 2 antimicrobial susceptibility testing (AST) for bacteria from positive blood culture bottles.Direct AST were performed in parallel to standard methods monomicrobial bottles. In total, 254 isolates grown on aerobic and/or anaerobic bottles identified with MALDI-TOF MS (bioMérieux, France), 1,978...
Context.— Infectious gastroenteritis is caused by various pathogens, including bacteria, viruses, and parasites. Objective.— To compare the performance of Seegene Allplex Gastrointestinal (24 targets: 13 5 6 parasites in 4 panels), Luminex xTAG Pathogen Panel (15 9 3 parasites), BD MAX Enteric panel (5 bacteria parasites). We estimated agreement among molecular assays. Design.— A total 858 stool samples (554 bacterial/parasite 304 viral pathogens) were included. consensus positive/negative...
Global data on the epidemiology and susceptibility of Aspergillus are crucial in management invasive aspergillosis. Here, we aimed to determine characteristics clinical environmental isolates, focusing mainly hematologic malignancy patients.
Background Serum procalcitonin (PCT) and C-reactive protein (CRP) are biomarkers of infection. In patients with hematologic disorders or without hematopoietic stem cell transplantation (HSCT), it is difficult to distinguish bloodstream infections from aseptic causes febrile episodes. The objective this study was investigate diagnostic values PCT CRP in predicting systemic bacterial infection malignancies. Methods Clinical laboratory data 614 episode cases 511 were analyzed. Febrile episodes...
individual with diabetes because the setpoint itself can (and often does) change over time.In summary, these data suggest that between-subject variation in GHb is minimal and therefore not a major consideration when used for routine clinical care.Assay quality, however, an important factor interpreting results (16 -18 ), imprecise assays may compromise utility of test.
We applied the new clinical breakpoints (CBPs) of Clinical and Laboratory Standards Institute (CLSI) to a multicenter study determine antifungal susceptibility bloodstream infection (BSI) isolates Candida species in Korea, determined relationship between frequency antifungal-resistant BSI use at hospitals. Four hundred fifty were collected over 1-year period 2011 from nine The susceptibilities four agents using CLSI M27 broth microdilution method. By applying species-specific CBPs,...
ObjectivesWe investigated the occurrence and mechanism of amikacin resistance its association with various β-lactamase genes in Pseudomonas aeruginosa isolates.
Neutrophils play an important role in immunological function. Neutropenic patients are vulnerable to infection, and except fever is present, inflammatory reactions scarce many cases. Additionally, because infections can worsen rapidly, early evaluation treatments especially febrile neutropenic patients. In cases which neutropenia anticipated due anticancer chemotherapy, antibiotic prophylaxis be used, based on the risk of infection. Antifungal may also considered if long-term or mucosal...
Periodic monitoring of regional or institutional resistance trends clinically important anaerobic bacteria is recommended, because the pathogens to antimicrobial drugs and inappropriate therapy are associated with poor clinical outcomes. There has been no multicenter study isolates in Korea. We aimed determine patterns anaerobes at multiple centers Korea.A total 268 non-duplicated were collected from four large medical Korea 2012. Antimicrobial susceptibility was tested by agar dilution...