A5091703720- Ion Channels and Receptors
- Intracranial Aneurysms: Treatment and Complications
- Ion channel regulation and function
- Cancer-related molecular mechanisms research
- Ginseng Biological Effects and Applications
- Connexins and lens biology
- Toxic Organic Pollutants Impact
- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Periodontal Regeneration and Treatments
- Gastrointestinal motility and disorders
- Fungal Plant Pathogen Control
- Prenatal Substance Exposure Effects
- Plant Stress Responses and Tolerance
- Cancer, Hypoxia, and Metabolism
- Pineapple and bromelain studies
- Bacterial Identification and Susceptibility Testing
- Testicular diseases and treatments
- Effects of Environmental Stressors on Livestock
- Anesthesia and Pain Management
- Tendon Structure and Treatment
- Herbal Medicine Research Studies
- Intraocular Surgery and Lenses
- Spinal Cord Injury Research
- Lipid metabolism and biosynthesis
Gyeongsang National University
2013-2024
Kyungpook National University
2016-2024
Although heat-shock transcription factors are well characterized in the heat stress-related pathway, they poorly understood other stress responses. Here, we functionally AtHsfA6a presence of exogenous abscisic acid (ABA) and under high salinity dehydration conditions. expression normal conditions is very low, but was highly induced by ABA, NaCl drought. Unexpectedly, levels transcript were not significantly altered cold stresses. Electrophoretic mobility shift assays transient...
Models created by the intraperitoneal injection of lipopolysaccharide (LPS) and D-galactosamine (D-GalN) have been widely used to study pathogenesis human acute liver failure (ALF) drug development. Our previous reported that oyster (Crassostrea gigas) hydrolysate (OH) had a hepatoprotective effect in LPS/D-GalN-injected mice. This was performed identify tyrosine-alanine (YA) peptide, main component OH, ALF mice model. We analyzed YA on previously known mechanisms hepatocellular injury...
The association between asthma and oxidative stress remains controversial. Oxidative stress-induced ferroptosis has not been extensively studied in models. This study was performed to investigate the anti-asthmatic anti-ferroptotic effects of fermented aged ginseng sprouts (FAGS) with enhanced antioxidant activity its main component, compound K (CK), a mouse model ovalbumin (OVA)-induced allergic asthma. experimental sensitized challenged OVA. During challenge period, two different...
Acute lung injury (ALI) is a condition associated with acute respiratory failure, resulting in significant morbidity and mortality. It involves cellular changes such as disruption of the alveolar-capillary membrane, excessive neutrophil migration, release inflammatory mediators. Broncho-Vaxom
Accumulative alcohol hangovers cause liver damage through oxidative and inflammatory stress. Numerous antioxidant anti-inflammatory reagents have been developed to reduce hangovers, but these are still insignificant limitations in that they can toxicity. Oyster hydrolysate (OH), another reagent has activity, is a product extracted an enzymatic hydrolysis process from oysters (Crassostrea gigas), which be easily eaten meals. This study was aimed at determining the effects of OH on metabolism,...
Prolotherapy is a proliferation therapy as an alternative medicine. A combination of dextrose solution and lidocaine usually used in prolotherapy. The concentrations the clinical field are very high (dextrose 10%-25%, 0.075%-1%). Several studies show about 1% more than 0.2% induced cell death various types. We investigated effects low fibroblasts suggest optimal range prolotherapy.Various were treated NIH-3T3. Viability was examined with trypan blue exclusion assay...
Our previous study showed that oyster hydrolysate (OH) protected against the liver damage caused by a single instance of ethanol (EtOH) binge drinking. Oyster broth concentrate (OBC) was discovered in process searching for different substance derived from oysters (
Garlic, a once-a-year crop, is mass-produced in single event. Most of the garlic harvested during year, unless consumed or processed immediately, should be stored. Stored raw (SRG) can used to make black (BG) via aging, and storage may affect properties quality BG compared with use that has not been This study was performed identify effect long-term on products. SRG aged for 21 days at 40-86 °C production. Moisture content pH gradually decreased aging period. Total phenolic, total flavonoid,...
Ovarian cysts are linked to hormone imbalances and altered gene expressions, but the connection between ion channel expression is understudied. This study explored role of TWIK-related acid-sensitive K+ (TASK) channels in bovine ovarian cyst formation. The follicles were split into small (5 10 mm diameter) large (> 25 groups. Among measured K+, Na+, Cl- concentrations follicular fluid (FF) obtained from small-sized (SF) large-sized (LF), concentration was significantly lower LFFF....
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher we support invest in the microbiology community, to benefit of everyone. This supports our principal goal develop, expand strengthen networks available members so that they can generate new knowledge about microbes ensure it is shared with other communities.
TWIK (tandem-pore domain weak inward rectifying K+)-related spinal cord K+ channel (TRESK), a member of the two-pore family, is abundantly expressed in dorsal root ganglion (DRG) neurons. It well documented that TRESK expression changed several models peripheral nerve injury, resulting shift sensory neuron excitability. However, role model injury (SCI) has not been fully understood. This study investigates thoracic contusion model, and transgenic mice overexpressed with gene (TGTRESK)....
We retrospectively analyzed clinical data to evaluate the safety and efficacy of single antiplatelet therapy (SAPT) after stent-assisted coil embolization (SAC) for ruptured cerebral aneurysms.
Reconstruction methods, including stent-assisted coiling, multiple telescopic stents, and flow diverters, are preferred modalities for the treatment of unruptured vertebral artery dissecting aneurysms (VADAs). We aimed to compare clinical outcomes between two reconstructive diversion techniques: single diverter (FD) device stenting (TS).
Platelet-derived growth factor receptor alpha (PDGFRα), a member of the tyrosine kinase family, activates
Ovarian cysts are linked to hormone imbalances and altered gene expressions, but the connection between ion channel expression is understudied. This study explored role of TWIK-related acid-sensitive K+ (TASK) channels in bovine ovarian cyst formation. The follicles were split into small (5 10 mm diameter) large (>25 groups. Among measured K+, Na+, Cl− concentrations follicular fluid (FF) obtained from small-sized (SFs) large-sized (LFs), concentration was significantly lower LFFF....
Mangifera indica L., a member of the Anacardiaceae family, is widely cultivated across globe. The leaves M. are renowned for their medicinal properties, attributed to abundance bioactive compounds. This study investigated effects mango leaf extract on oxidative stress in HeLa cells. Notably, n-hexane fraction (MLHx) significantly enhanced antioxidant response element (ARE)-luciferase activity at concentration 100 µg/mL, surpassing other fractions. MLHx also promoted expression HO-1 mRNA by...
ABSTRACT Fermented and aged mountain‐cultivated ginseng sprouts (FAMCGS) exhibit superior antioxidant anti‐inflammatory properties compared to (MCGS). However, the mechanisms behind these of FAMCGSE remain unclear. This study explores effects FAMCGS extract (FAMCGSE) on LPS‐stimulated RAW 264.7 macrophages underlying mechanisms. The MTT assay confirmed that (0 0.1%) maintained cell viability without inducing morphological changes. Pretreatment with significantly mitigated LPS‐induced...
Growth arrest and DNA damage-inducible beta (GADD45b) plays a critical role in intracellular events such as cell growth apoptosis. Although the functional study of GADD45b has been conducted, mechanism for transcriptional regulation is largely unknown. Due to drastic induction hepatic mRNA by peroxisome proliferator-activated receptor alpha (PPARα) activation wild-type mice, we investigated key factor that affects upregulation mRNA. Interestingly, found GADD45b-promoter luciferase activity...
Leydig cells are located in the interstitial tissue of testes and responsible for producing secreting testosterone.Testosterone is essential development male reproductive structure, secondary sexual characteristics, overall physiology.Gene expression patterns affect testosterone levels, which turn germ cell proliferation maturation, thus spermatogenesis (O'Shaughnessy et al., 2002; Jauregui 2018).Our recent study found that express c-Kit, a receptor tyrosine kinase Kit, anoctamin 1 (ANO1),...
Receptor tyrosine kinase c-Kit, a marker found on interstitial cells of Cajal (ICCs), is expressed in Leydig cells, which are testicular cells.The expression other ICC markers has not yet been reported.In this study, we investigated the c-Kit and anoctamin 1 (ANO1), another marker, mouse testes.In addition, relationship between ANO1 cell function was investigated.We observed that were predominantly mRNA protein TM3, line.LH induced an increase intracellular Ca 2+ concentration, membrane...
Eun-Jin Kim, Long Cao Dang, Marie Merci Nyiramana, Adrian S. Siregar, Min-Seok Woo, Chang-Woon Kim and Dawon Kang. Journal of Animal Reproduction Biotechnology 2021;36:145-53. https://doi.org/10.12750/JARB.36.3.145
Introduction Proliferative vitroretinopathy (PVR) is a major cause of failure in surgery rhegmatogenous retinal detachment (RRD). The incidence PVR approximately attains up to 5~10% RDD and 75% redetachment after surgery, however, the strategy for precautions or resolving very limited. Lidocaine well known widely used local anesthetics. We evaluated effects lidocaine on epithelial‐mesenchymal transition (EMT) migration pigment epithelial cells, which cell type involved development PVR, its...