A5016241392- Asthma and respiratory diseases
- Urticaria and Related Conditions
- Allergic Rhinitis and Sensitization
- Drug-Induced Adverse Reactions
- Autoimmune Bullous Skin Diseases
- Respiratory and Cough-Related Research
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mast cells and histamine
- Eosinophilic Disorders and Syndromes
- Tuberculosis Research and Epidemiology
- Pharmacovigilance and Adverse Drug Reactions
- Inhalation and Respiratory Drug Delivery
- Pediatric health and respiratory diseases
- Olfactory and Sensory Function Studies
- Respiratory Support and Mechanisms
- Mycobacterium research and diagnosis
- Lung Cancer Diagnosis and Treatment
- Eosinophilic Esophagitis
- Infectious Diseases and Tuberculosis
- Lung Cancer Treatments and Mutations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Hallym University
2014-2024
Hallym University Dongtan Sacred Heart Hospital
2015-2024
Catholic University of Korea
2017-2023
Karolinska Institutet
2014-2021
Chung-Ang University
2019
Dong-A University Hospital
2017
Hallym University Sacred Heart Hospital
2009-2014
Karolinska University Hospital
2014
Asan Medical Center
2014
Andong Science University
2013
Pollen-food allergy syndrome (PFAS) is an immunoglobulin E (IgE)-mediated in pollinosis patients caused by raw fruits and vegetables the most common food adults. However, there has been no nationwide study on PFAS Korea. In this study, we investigated prevalence clinical characteristics of Korea.Twenty-two investigators participated which with allergic rhinoconjunctivitis and/or bronchial asthma pollen were enrolled. The questionnaires included demographic characteristics, a list vegetables,...
Although several recent studies reported that probiotics might be beneficial for allergic rhinitis (AR), the effect of on AR is not consistent and have been reproduced between studies. We aimed to determine efficacy safety probiotic NVP-1703, a mixture Bifidobacterium longum Lactobacillus plantarum, in subjects with perennial AR. Adult received either NVP-1703 (n = 47) or placebo 48) four weeks. Total nasal symptom scores (TNSS), control assessment test (RCAT), blood eosinophil count,...
Background Limited research exists on Pneumocystis jirovecii pneumonia (PJP) in hemodialysis (HD) patients. This retrospective study aimed to compare clinical features and outcomes of PJP HD non-HD Methods We retrospectively analyzed 10 cases 40 which were matched propensity scoring. Criteria included respiratory symptoms, new pulmonary infiltrates, positive real-time PCR. patients excluded if they taking immunosuppressants, receiving solid organ transplant, treatment for hematological or...
Bee pollen is granules packed by honey bees and widely consumed as natural healthy supplements. pollen-induced anaphylaxis has rarely been reported, its allergenic components have never studied. A 40-year-old male came to the emergency room with generalized urticaria, facial edema, dyspnea, nausea, vomiting, abdominal pain, diarrhea 1 hour after ingesting one tablespoon of bee pollen. Oxygen saturation was 91%. His symptoms resolved injection epinephrine, chlorpheniramine, dexamethasone. He...
Although prognostic prediction scores for pneumonia such as CURB-65 score or severity index (PSI) are widely used, there were a few studies in very elderly patients. The aim of the study was to validate severe and investigate risk factors associated with in-hospital mortality patients.During 6-year period (from October 2012 May 2018), 160 patients aged 80 older admitted medical intensive unit analyzed retrospectively. Pneumonia evaluated using score, PSI, Sequential Organ Failure Assessment...
Abstract Purpose Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but serious condition that systematically damages various internal organs through T‐cell–mediated immunological drug reactions. We aimed to investigate whether clinical manifestations of DRESS differ according culprit drugs. Methods retrospectively analyzed data from 123 patients probable/definite based on the RegiSCAR criteria (January 2011 July 2016). The were obtained Korean Severe Cutaneous...
Understanding the interaction between nanoparticles and immune cells is essential for evaluation of nanotoxicity development nanomedicines. However, to date, there little data on membrane microstructure biochemical changes in nanoparticle-loaded cells. In this study, we observed macrophages lipid droplets using holotomography analysis. Quantitatively analyzing refractive index distribution macrophages, identified interactions macrophages. The results showed that, when were phagocytized by...
Many studies have reported that pollen-food allergy syndrome (PFAS) can cause anaphylaxis. No comprehensive investigations into anaphylaxis in PFAS been conducted, however. In this study, we investigated the clinical manifestations and risk factors for Korean patients with pollinosis.Data were obtained from a nationwide cross-sectional study previously on pollinosis. Data 273 collected, including demographics, list of culprit fruits vegetables, food allergy. We analyzed 27 compared them...
Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia systemic symptoms (DRESS) to antiepileptic (AED), are rare, but result in significant morbidity mortality. We investigated the major culprit drugs, clinical characteristics, course outcomes of AED-induced SCARs using a nationwide registry Korea.A total 161 patients from 28 referral hospitals were analyzed. The causative AEDs, organ...
Adverse drug reactions (ADRs) to first-line anti-tuberculosis (TB) drugs are common; however, there have been few reports of nationwide epidemiologic studies on ADRs anti-TB in Korea. This study aimed investigate the clinical characteristics various using a database ADRs.We used Korea Event Reporting System (KAERS) (2009-2018). The subjects were selected Korean Standard Classification Diseases codes for pulmonary and extrapulmonary TB electronic data interchange isoniazid (INH), rifampicin...
Purpose: As pet ownership increases, sensitization to animal allergens due domestic exposure is a concern.Sensitization may occur from indirect exposure, as well direct of animals.However, there have been conflicting results regarding the association between and in adults.Methods: In total, 401 patients with various allergic diseases were enrolled this study.We performed skin prick tests 55 common inhalant food allergens, including dog, cat, rabbit allergens.A mean wheal diameter 3 mm or...
The basophil activation test (BAT) has been suggested as a complementary method for diagnosing drug allergies.The aim of this study was to evaluate the clinical utility in patients with drug-induced anaphylaxis.In total, 19 patients, all whom had history moderate severe anaphylaxis, were enrolled.None causative drugs available vitro tests or reliable skin tests; these included, among others, first and second-generation cephalosporins, H2 blockers, muscle relaxants.The BAT yielded positive...