- Marine and coastal plant biology
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Marine Bivalve and Aquaculture Studies
- Seaweed-derived Bioactive Compounds
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Food Quality and Safety Studies
- Allergic Rhinitis and Sensitization
- Inhalation and Respiratory Drug Delivery
- Marine Biology and Ecology Research
- Urticaria and Related Conditions
- Eosinophilic Esophagitis
- Echinoderm biology and ecology
- Probiotics and Fermented Foods
- Eosinophilic Disorders and Syndromes
- Enzyme Production and Characterization
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Coastal wetland ecosystem dynamics
- Plant Pathogens and Resistance
- Food Industry and Aquatic Biology
- Plant Pathogens and Fungal Diseases
- Autoimmune Bullous Skin Diseases
- Nematode management and characterization studies
- Food Allergy and Anaphylaxis Research
Inje University
2018-2025
Inje University Haeundae Paik Hospital
2015-2024
Mokpo National University
2010-2023
Korea Research Institute of Bioscience and Biotechnology
2009-2023
Seoul National University
2019
Chungbuk National University Hospital
2018
Chungbuk National University
2007-2016
Inje University Ilsan Paik Hospital
2013
University of Ulsan
2005-2010
Asan Medical Center
2005-2010
Mariculture is regarded as the only option to supply increasing demands for seaweeds human food, feeds, fodder, and phycolloids in a sustainable manner. Technologies culturing range of seaweed species have been developed successively Korea since 1970s. In 2017, Korean marine farms produced 1,761,526 t seaweed. The key focus industry on production Pyropia (523,648 t), Undaria (622,613 Saccharina (542,285 t). economically most important Korea, accounting up 68% total value. As top exporter...
Background/Aims Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed investigate the presence of anxiety, depression, and stress in Korean adult CU patients explore their potential impact on treatment. Methods enrolled 79 a disease control group comprising 39 persistent asthma patients. The Hospital Anxiety Depression Scale (HADS) was used evaluate depression anxiety. Stress quality life (QoL) were assessed by Response Inventory CU-QoL questionnaires....
Severe asthma is associated with high morbidity and healthcare utilization; however, treatment options for these patients are limited. This study aimed to determine the therapeutic effects of biologics in clinical practice. multicenter, retrospective cohort included 136 who received at least 4 months between September 2017 July 2022 25 medical centers affiliated Korean Asthma Registry (KoSAR). The evaluated effects, including acute exacerbation rates, maintenance oral corticosteroid dosages,...
Background The relationship between pre-treatment levels of blood eosinophil count (BEC), fractional exhaled nitric oxide (FeNO), and sputum eosinophils (Sp-EOS) treatment response to monoclonal antibodies (mAbs) in severe eosinophilic asthma (SEA) remain unclear. Objective We evaluated BEC, FeNO, Sp-EOS, their combinations as predictors responses patients with SEA undergoing anti-IL5/IL5Rα or anti-IL-4Rα antibody therapies. Methods study included 153 adult (59 94 anti-IL4Rα users). Logistic...
Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia systemic symptoms (DRESS) to antiepileptic (AED), are rare, but result in significant morbidity mortality. We investigated the major culprit drugs, clinical characteristics, course outcomes of AED-induced SCARs using a nationwide registry Korea.A total 161 patients from 28 referral hospitals were analyzed. The causative AEDs, organ...
Abstract Different patterns of bacterial communities have been reported in the airways and gastrointestinal tract asthmatics when compared to healthy controls. However, blood microbiome is yet be investigated. Therefore, we aimed determine whether a distinct serum observed by metagenomic analysis extracellular vesicles (EVs). We obtained from 190 adults with asthma 260 controls, which EVs were isolated analyzed. The composition was significantly different that Chao 1 index higher group,...
Interstitial lung diseases (ILDs) are chronic, parenchymal with a variable clinical course and poor prognosis. Within various courses, acute exacerbation (AE) is devastating condition significant morbidity high mortality. The aim of this study was to investigate the role interleukin-6 (IL-6) predict AE prognosis in patients ILD.Eighty-three who were diagnosed ILD from 2016 2019 at Haeundae Paik Hospital, Busan, South Korea, included their data retrospectively analyzed.The median follow-up...
Abstract Purpose This study was conducted to evaluate the effectiveness of a computerized surveillance system for adverse drug events (ADEs) reinforced with mandatory reporting all past hypersensitivity reactions (DHSRs) and supervision processes by allergy specialists in university hospital. Methods All information on both prior newly developed DHSRs collected via described above compared data from previous based voluntary attending physicians. Results The report rate greatly increased...
with mild intermittent asthma. 4,6he most direct way of assessing airway remodeling is by histological examination lung biopsy specimens.Alternatively, pulmonary function testing (PFT), which has been used in clinical settings and epidemiological studies, can link changes mechanical properties airways remodeling.
<b><i>Background:</i></b> Hereditary angioedema (HAE) is a genetically heterogeneous autosomal dominant disorder characterized by recurrent episodes of nonpruritic, nonpitting edema increasing after puberty. It can be fatal due to laryngeal or gastrointestinal (GI) involvement with varied and changing frequency mortality according studies published from the Western countries. Epidemiological clinical data HAE in Asian countries are sparse. We sought examine...
Abstract Background While the clinical characteristics and outcomes of asthma‐chronic obstructive pulmonary disease (COPD) overlap (ACO) have been frequently compared with those COPD or asthma, prevalence features ACO in patients severe asthma are unclear. Objectives Evaluation using Korean registry. Methods At time registration, was determined by attending specialists. Patients were classified into non‐ACO groups, demographic these two groups compared. Results Of 482 23.7% had ACO. group...
Oral corticosteroids (OCS) are commonly used in patients with severe asthma, but they associated several adverse events. We estimated the prevalence of OCS-dependent asthma a large nationwide registry for and delineated their clinical characteristics.This cross-sectional study analyzed enrollment data recruited Korean Severe Asthma Registry (KoSAR) from 2010 to 2019. The characteristics were compared according OCS dependency, which was defined as maintenance treatment lasting at least 6...