A5009072248- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Pharmacovigilance and Adverse Drug Reactions
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Pharmaceutical studies and practices
- Contact Dermatitis and Allergies
- SARS-CoV-2 and COVID-19 Research
- Infection Control and Ventilation
- COVID-19 and Mental Health
- Medical Malpractice and Liability Issues
- COVID-19 and healthcare impacts
- Patient Satisfaction in Healthcare
- Antibiotics Pharmacokinetics and Efficacy
- Respiratory and Cough-Related Research
- Patient-Provider Communication in Healthcare
- Antimicrobial Resistance in Staphylococcus
- Patient Safety and Medication Errors
- Autoimmune Bullous Skin Diseases
- RNA Interference and Gene Delivery
- Health and Medical Research Impacts
- Infection Control in Healthcare
- Healthcare and Environmental Waste Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Harvard University
2014-2023
Brigham and Women's Hospital
2014-2023
University of Mississippi Medical Center
2020
State Street (United States)
2020
American College of Allergy, Asthma and Immunology
2020
Chestnut Hill College
2014-2017
Yale University
2011
Dartmouth–Hitchcock Medical Center
2004
38.3%) were tested on days 9 to 14.Of the 134 student contacts day 3, 14 (10.4%) positive for SARS-CoV-2 infection.Of 839 14, 40 (4.8%) 388 in high school who tested, 32 (8.2%) infection compared with 8 (1.8%) of 451 elementar y and middle (P < .001;Table ).Among 799 confirmed COVID-19 cases a negative test result only 1 became symptomatic after returning had an initial 9.The virus from this was genetically distinct isolated case which been exposed (GenBank case: MW307809; GenBank 9-day...
BackgroundThe Centers for Disease Control and Prevention state that a severe or immediate allergic reaction to the first dose of an mRNA COVID-19 vaccine is contraindication second dose.ObjectiveTo assess outcomes associated with excipient skin testing after reported vaccine.MethodsWe identified consecutive sample patients reactions who underwent allergy assessment polyethylene glycol (PEG) and, when appropriate, polysorbate 80. Skin results in conjunction clinical phenotyping first-dose...
Reported penicillin allergy rarely reflects intolerance. Failure to address inpatient allergies results in more broad-spectrum antibiotic use, treatment failures, and adverse drug events.We aimed determine the optimal approach among medical inpatients.We evaluated internal medicine inpatients reporting 3 periods: (1) standard of care (SOC), (2) skin testing (ST), (3) computerized guideline application with decision support (APP). The primary outcome was use a or cephalosporin, comparing...
Objective There have been growing concerns about the impact of drug allergy alerts on patient safety and provider alert fatigue. The authors aimed to explore common over last 10 years reasons why providers tend override these alerts. Design: Retrospective observational cross-sectional study (2004–2013). Materials Methods Drug data (n = 611,192) were collected from two large academic hospitals in Boston, MA (USA). Results Overall, found an increase rate overrides, 83.3% 2004 87.6% 2013 (P...
Abstract Objective: To assess the safety of, and subsequent allergy documentation associated with, an antimicrobial stewardship intervention consisting of test-dose challenge procedures prompted by electronic guideline for hospitalized patients with reported β-lactam allergies. Design: Retrospective cohort study. Setting: Large healthcare system 2 academic 3 community acute-care hospitals between April 2016 December 2017. Methods: We evaluated antibiotic outcomes, including adverse drug...
Abstract We report on COVID-19 risk among HCWs exposed to a patient diagnosed with day 13 of hospitalization. There were 44 the before contact and droplet precautions implemented: these, 2 (5%) developed potentially attributable exposure.
Many patients are fearful of acquiring coronavirus disease 2019 (COVID-19) in hospitals and clinics. We characterized the risk COVID-19 among 226 exposed to healthcare workers with confirmed COVID-19. One patient may have been infected, suggesting that transmission from is generally low.
<h3>Importance</h3> Although critical to patient safety, health care–related allergic reactions are challenging identify and monitor. <h3>Objective</h3> To develop a deep learning model in the free-text narrative of hospital safety reports evaluate its generalizability, efficiency, productivity, interpretability. <h3>Design, Setting, Participants</h3> This cross-sectional study analyzed filed between May 2004 January 2019 at Brigham Women's Hospital April 2006 June 2018 Massachusetts General...
Clinical Implications•Allergic symptoms after dose 1 of mRNA coronavirus disease 2019 (COVID-19) vaccine may contribute to incomplete vaccination. However, most patients with mild or nonimmediate can safely complete Allergists must be prepared counsel prevent •Allergic Allergic reactions have been reported Anaphylaxis the first is a contraindication subsequent vaccination; however, many allergic are not.1U.S. Centers for Disease Control and PreventionCOVID-19...
<h3>Importance</h3> Allergic history in individuals with confirmed anaphylaxis to a messenger RNA (mRNA) COVID-19 vaccine is common. However, the risk factors for allergy symptoms after receiving are unknown. <h3>Objective</h3> To assess association between self-reported of high-risk and allergic reactions mRNA vaccination health care employees. <h3>Design, Setting, Participants</h3> This cohort study obtained demographic, medical, administration data employees Mass General Brigham from...
<b><i>Background:</i></b> Hereditary angioedema (HAE) is a genetically heterogeneous autosomal dominant disorder characterized by recurrent episodes of nonpruritic, nonpitting edema increasing after puberty. It can be fatal due to laryngeal or gastrointestinal (GI) involvement with varied and changing frequency mortality according studies published from the Western countries. Epidemiological clinical data HAE in Asian countries are sparse. We sought examine...