A5050445204- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Biliary and Gastrointestinal Fistulas
- Neuroendocrine Tumor Research Advances
- Metastasis and carcinoma case studies
- Gastroesophageal reflux and treatments
- Abdominal vascular conditions and treatments
- Medical Imaging and Pathology Studies
- Gastrointestinal Tumor Research and Treatment
- Appendicitis Diagnosis and Management
- Esophageal Cancer Research and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Genetic factors in colorectal cancer
- Tuberculosis Research and Epidemiology
- Neuropeptides and Animal Physiology
- Renal and Vascular Pathologies
Chungbuk National University
2016-2025
Chungbuk National University Hospital
2014-2025
New Generation University College
2013-2023
National University College
2013-2023
Sungshin Women's University
2023
Seoul National University
2023
Samsung Medical Center
1997-2020
Sungkyunkwan University
1997-2018
Translational Genomics Research Institute
2018
University of Ulsan
2017
Circulating cell-free microRNAs (miRNAs) are potential cancer biomarkers. The aim of this study was to identify miRNAs that differentially expressed between benign pleural effusion (BPE) and lung adenocarcinoma-associated malignant (LA-MPE). expression level miRNA investigated in 107 patients with effusion. Microarrays were used screen 160 a discovery set comprising 20 samples (ten BPEs ten LA-MPEs). Real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) validate...
Although remimazolam is an ultra-short-acting benzodiazepine with a shorter elimination half-life and faster recovery time than midazolam, studies evaluating its safety efficacy during bronchoscopy are limited. This study aimed to compare the of those midazolam for bronchoscopy. prospective randomized parallel-group was conducted at single institution. The primary outcome from end procedure full alertness. Other procedural parameters, satisfaction profiles, adverse effects were thoroughly...
Currently, a new over-the-scope clip (OTSC) system has been introduced. This used for gastrointestinal perforations and fistulas in other countries. The aim of our study is to examine the therapeutic success rate endoscopic treatment using OTSC Korea.This was multicenter prospective study. A total seven endoscopists at centers performed this procedure.A 19 patients were included, with leakages from anastomosis sites, fistulas, or esophageal due Boerhaave's syndrome. Among these, there three...
Abstract Background The TeloVac study indicated GV1001 did not improve the survival of advanced pancreatic ductal adenocarcinoma (PDAC). However, cytokine examinations suggested that high serum eotaxin levels may predict responses to GV1001. This Phase III trial assessed efficacy with gemcitabine/capecitabine for eotaxin-high patients untreated PDAC. Methods Patients recruited from 16 hospitals received gemcitabine (1000 mg/m 2 , D 1, 8, and 15)/capecitabine (830 BID 21 days) per month...
Typical CT findings of active postprimary pulmonary tuberculosis include centrilobular nodules and branching linear structures (tree-in-bud appearance), lobular consolidation, cavitation, bronchial wall thickening. The inactive calcified or irregular opacity, parenchymal bands, pericicatricial emphysema. typical appearance primary on scans is homogeneous, dense, well-defined segmental lobar consolidation with enlargement lymph nodes in the hilum mediastinum. Miliary may be seen tuberculosis....
Endoscopic ultrasound-guided fine needle aspiration (EUSFNA) and brushing cytology are used worldwide to diagnose pancreatic biliary malignant tumors. Liquid-based (LBC) has been developed it is currently overcome the limitations of conventional smears (CS). In this study, authors aimed compare diagnostic value CellPrepPlus (CP; Biodyne) LBC method with CS in samples obtained using EUS-FNA cytology.This study prospectively enrolled 75 patients or lesions from June 2012 October 2013. For...
Abstract We aimed to evaluate the incidence and risk of pancreatic cancer (PC) in pancreatitis. identified patients with acute pancreatitis (AP) (n = 225,811, 50.0%) chronic (CP) 225,685, from Korean population-based data matched them age- sex-matched controls 4,514,960). analyzed adjusted hazard ratios (aHRs) PC among followed for more than 2 years or 5 years, assessed changes over time single episode AP (SAP), recurrent (RAP), CP AP, without groups. also performed subgroup analysis both...
Abstract Maspin inhibits metastasis of some cancer cells, and clinical studies have identified correlations between maspin loss poor prognosis in several types. was found to be significantly overexpressed lung samples as compared with matched normal tissues. However, the regulatory mechanism expression remains unclear. We show here that differential carcinoma-derived cells is regulated at transcriptional level. p63 a critical factor for transcription maspin, which lost highly invasive such...
Background and aim Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is commonly used to obtain tissue external the gastrointestinal tract. EUS-FNA relatively safe, but occasionally adverse events have been reported. There scarcity of data on risk factors events. The this study identify associated with EUS-FNA. Methods In multicenter case-control study, we retrospectively reviewed 4,097 cases between 2009 2012 at 15 hospitals in Korea. Among patients there were 104 (2.5%) who had...
Intraductal tubulopapillary neoplasm (ITPN) has been recently reported in pancreas. We experienced an unusual intraductal growing bile duct tumor, which showed the same histopathologic and immunostaining profiles as ITPN of A 72-year-old female patient visited hospital due to intrahepatic stone. The hilar tumor was detected incidental lung mass found systemic evaluation. finding two biopsy lesions different. adenocarcinoma, poorly differentiated carcinoma with eosinophilic cytoplasm. Lung...
Iatrogenic gastric perforation is one of the most serious complications during therapeutic endoscopy, despite significant advances in endoscopic techniques and devices.This case study evaluated clinical efficacy safety rescue band ligation (EBL) technique iatrogenic wall following failure primary endoclip closure.Five patients were enrolled this study.These underwent emergency endoscopy onset acute procedures.The outcome measurements technical success immediate or delayed procedure-related...
Liquid‐based cytology (LBC) is being increasingly used for body fluid specimens and has improved diagnostic accuracy when compared to conventional smears. We the cellular morphologic features between CellprepPlus® LBC ThinPrep® in effusion cytology. One hundred eighty specimens, consisting of 119 pleural 59 peritoneal 2 pericardial were obtained from 166 patients. Equal volumes each specimen preparations. Sensitivity, specificity, positive negative predictive values evaluated. In addition,...
Background/Aims Ampullary tumors come in a wide variety of malignant forms. We evaluated the diagnostic accuracy endoscopy for ampullary tumors, and analyzed causes misdiagnosis. Methods compared endoscopic imaging biopsy results to final diagnoses. Types endoscope, numbers specimens taken, diagnoses were as possible factors influencing accuracy. Results Final 19 adenocarcinomas, 18 normal or papillitis, 11 adenomas, two adenomyomas, one paraganglioma, neuroendocrine tumor. The initial was...
Pulmonary lymphangioleiomyomatosis (LAM) is an uncommon disease that to this point has been known occur exclusively in reproductive women. To our knowledge, only one case of pulmonary LAM was proven pathologically reported a genotypical and phenotypical man. Multiple occurrence hepatic angiomyolipomas also rare, six cases have found the literature. Here, we report biological man who had multiple angiomyolipomas, leading presumptive diagnosis tuberous sclerosis. This unsual presentation...