A5091134003- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- Pancreatitis Pathology and Treatment
- Orbital Angular Momentum in Optics
- Liver Disease Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Radical Photochemical Reactions
- Peptidase Inhibition and Analysis
- Fluorine in Organic Chemistry
- Cancer Cells and Metastasis
- Tumors and Oncological Cases
- Liver Disease and Transplantation
CHA University
2024-2025
Gumi University
2024-2025
Pusan National University Hospital
2015-2024
Pusan National University
2015-2024
New Generation University College
2012-2024
Kyungpook National University
2024
National University College
2012-2024
Kyungpook National University Hospital
2024
Biomedical Research Institute
2012-2023
Korea Basic Science Institute
2020-2021
OBJECTIVES: The goal of the study was to determine whether endoscopic ultrasound (EUS)-guided biliary drainage (EUS-BD) is comparable conventional transpapillary stenting with retrograde cholangiopancreatography (ERCP) in palliation malignant distal obstruction. Although ERCP for obstruction standard care, post-procedure pancreatitis and stent dysfunctions are not uncommon. While EUS-BD has garnered interest as a viable alternative when impossible, its role primary yet be proven. METHODS: We...
<h3>Objectives:</h3> To determine the immediate and long-term therapeutic efficacies of barbecue rotation Gufoni maneuvers, a randomized, prospective, sham-controlled study was conducted in patients with geotropic type benign paroxysmal positional vertigo involving horizontal semicircular canal (HC-BPPV). <h3>Methods:</h3> In 10 nationwide dizziness clinics Korea, 170 consecutive (107 women, age range 11−97 years, mean ± SD 61 15 median = years) HC-BPPV were randomly assigned to (n 56), 64),...
No previous studies have investigated the relationship between various anti-ganglioside antibodies and clinical characteristics of Guillain-Barré syndrome (GBS) in Korea. The aim this study was to determine prevalence types Korean GBS patients, identify their significance. Serum collected from patients during acute phase at 20 university-based hospitals laboratory findings were reviewed compared with detected antibody. Among 119 60 positive for immunoglobulin G (IgG) or M against any type...
Abstract Episodic ataxia (EA) is a rare neurological condition characterized by recurrent spells of truncal and incoordination. Five genes ( KCNA1 , CACNA1A CACNB4 SLC1A3 UBR4 ) have been linked to EA. Despite extensive efforts genetically diagnose EA, many patients remain still undiagnosed. Whole-exome sequencing was carried out in 39 Korean with EA identify pathogenic mutations the five known genes. We also evaluated 40 candidate that cause as secondary phenotype or cerebellar ataxia....
Abstract Background and Aim: To perform endoscopic mucosal resection (EMR) for T1 esophageal cancer, it is essential to estimate the lymph node status exactly. In order evaluate feasibility of EMR cancers, we evaluated clinicopathological features squamous carcinomas with an emphasis on risk factors distribution patterns metastasis. Methods: From 1994 2006, a total 200 patients carcinoma were treated surgically in our institution. Among them, 197 consecutive cell carcinoma. Results: The...
Abstract Purpose We aimed to evaluate the efficacy and safety of temperature‐controlled intraductal radiofrequency ablation (ID‐RFA) for advanced malignant hilar biliary obstruction (MHBO). Methods Patients were randomly assigned RFA group (ID‐RFA bilateral plastic stent [PS]) or non‐RFA (bilateral PS) at a 1:1 ratio. Exchange self‐expanding metal (SEMS) was performed after 3 months when premature PS occlusion occurred. Total event‐free patency, overall survival (OS), adverse events (AEs)...
Research on the relationship between small-area-level deprivation and cancer survival, particularly for colorectal (CRC), is lacking. Therefore, we investigated among small area-level deprivation, individual-level factors, CRC survival using data from Busan Regional Cancer Registry. We analyzed 34,999 patients with Registry 2003 to 2020. The primary outcome was mortality. explanatory variables at individual level included age, gender, stage, year of diagnosis, whereas Deprivation Index (DI)...
Abstract Background Endoscopic treatments, such as endoscopic submucosal dissection (ESD) and laparoscopic gastrectomy, are increasingly used to treat a subset of patients with early gastric cancer (EGC). To achieve successful outcomes, it is very important accurately determine the lateral extent tumor. Therefore, we investigated diagnostic performance chromoendoscopy using indigo carmine dye added acetic acid (AI chromoendoscopy) in delineating differentiated or undifferentiated...
The development of endoscopic treatment, such as submucosal dissection, extends the indications for resection in patients with early gastric cancer (EGC). Endoscopic ultrasonography (EUS) is first-choice imaging modality determining depth invasion cancer. aim present study was to prospectively assess accuracy EUS EGC, according accepted/extended indications.We included a total 181 lesions 178 patients, an diagnosis who underwent staging tumor using 20-MHz catheter probe. We investigated...
Abstract Background Gastric intestinal metaplasia (IM) usually appears in flat mucosa and shows few morphologic changes, making diagnosis using conventional endoscopy unreliable. Magnifying narrow-band imaging (NBI) enables evaluation of detailed morphological features that correspond with the underlying histology. The aim this study was to investigate clarify diagnostic efficacy magnifying NBI endoscopic findings for prediction IM. Methods Forty-seven patients were prospectively enrolled,...
Objective: Infusion of the protease inhibitor nafamostat mesilate (20 mg) effectively prevents post-ERCP pancreatitis, but only in low-risk groups. This study was performed to evaluate use high-dose (50 for prevention pancreatitis (PEP), especially high-risk Methods: A total 608 patients who underwent ERCP were included; 13 excluded. Patients divided into 3 groups: controls (group A), infusion with 20 mg B), or 50 C). The incidence PEP analyzed. Results: overall acute 7.4% (44/595). There a...
<b><i>Background/Aims:</i></b> There is no standard consensus on a strategy in the second-line setting for gemcitabine-refractory advanced pancreatic cancer. This study evaluated activity and tolerability of oxaliplatin, irinotecan, 5-fluorouracil leucovorin (FOLFIRINOX) as therapy adenocarcinoma pretreated with gemcitabine-based regimen. <b><i>Methods:</i></b> A retrospective survey was carried out 18 patients cancer who had been chemotherapy...
Complementary and alternative medicine (CAM) has been used widely in various populations for purposes, including emotional support improvement of quality life (QOL). However, CAM use purposes using are less clear among Korean patients with a solid tumor. The purpose this study was to determine the prevalence type use, association between anxiety, depression, QOL tumor.A cross-sectional survey.A cancer center Korea.Two hundred sixteen diagnosed tumor.Standard questionnaires on Hospital...
OBJECTIVES: Successful biliary cannulation is a prerequisite and important component of endoscopic retrograde cholangiopancreatography, but conventional methods (CCMs) have postendoscopic cholangiopancreatography pancreatitis (PEP) rate 14.1% in patients at high risk for PEP. The aim this study was to evaluate the effectiveness safety needle-knife fistulotomy (NKF), compared with CCM, when used primary access developing METHODS: A total 207 one or more factors PEP were prospectively...
Circulating tumor cells (CTCs) are known to be heterogeneous and clustered with tumor-associated cells, such as macrophages, neutrophils, fibroblasts, platelets. However, their molecular profile clinical significance remain largely unknown. Thus, we aimed perform a comprehensive gene expression analysis of single CTCs CTC clusters in patients pancreatic cancer identify potential relevance provide personalized medicine. Epitope-independent, rapid (>3 mL whole blood/min) isolation was achieved...
Aim Antireflux plastic biliary stents prevent duodenal reflux and improve the stent patency rate. However, efficacy of antireflux valve in a self‐expandable metal ( SEMS ) for malignant obstruction has not been well established. We evaluated with an using vitro flow studies determined impact reducing duodenobiliary on Methods In testing was conducted bile perfusion system to evaluate antegrade retrograde resistance, determine ideal shape valve. Then, prospective case series humans adequately...