- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal disorders and treatments
- Congenital Diaphragmatic Hernia Studies
- Congenital gastrointestinal and neural anomalies
- Esophageal and GI Pathology
- Semiconductor Quantum Structures and Devices
- Congenital Anomalies and Fetal Surgery
- Hernia repair and management
- Pediatric Hepatobiliary Diseases and Treatments
- Tracheal and airway disorders
- GaN-based semiconductor devices and materials
- Gallbladder and Bile Duct Disorders
- Pelvic floor disorders treatments
- Neonatal Respiratory Health Research
- Intestinal and Peritoneal Adhesions
- Teratomas and Epidermoid Cysts
- Soft tissue tumor case studies
- Infant Nutrition and Health
- Lipid Membrane Structure and Behavior
- Semiconductor Lasers and Optical Devices
- Optical Coatings and Gratings
- Korean Urban and Social Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Appendicitis Diagnosis and Management
- Gastrointestinal Tumor Research and Treatment
Pusan National University Yangsan Hospital
2012-2022
Agency for Defense Development
2022
Pusan National University
2007-2021
Korea University Medical Center
2020
University of California, Los Angeles
2019
Korea Testing Certification
2018
Korea Advanced Institute of Science and Technology
2008-2017
Soonchunhyang University
2015-2016
Scripps Research Institute
2011
Pusan National University Hospital
2009-2010
Formation of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex provides mechanical thrust for membrane fusion, but its molecular mechanism is still unclear. Here using magnetic tweezers, we observe responses a single neuronal SNARE under constant pulling force. Single complexes may be unzipped with 34 pN When rezipping induced by lowering force to 11 pN, only partially assembled state results, C-terminal half remaining disassembled. Reassembly occurs...
White light-emitting diodes (LEDs) are becoming an alternative general light source, with huge energy savings compared to conventional lighting. However, white LEDs using phosphor(s) suffer from unavoidable Stokes converting losses, higher manufacturing cost, and reduced thermal stability. Here, we demonstrate electrically driven, phosphor-free, based on three-dimensional gallium nitride structures double concentric truncated hexagonal pyramids. The electroluminescence spectra stable varying...
Two-photon interference from an InAs/InAlGaAs quantum dot (QD) emitting in the telecom C-band with a raw two-photon visibility of $V_{HOM}=(71.9\pm0.2)$ % is demonstrated. This achieved by two-fold approach: improvement molecular beam epitaxial growth for better QDs, and integration QDs into optical circular Bragg grating resonator Purcell enhancement radiative decay rate. The properties fabricated device are studied means time-correlated single-photon counting under quasi-resonant...
Importance The potential benefits of P2Y12 inhibitor deescalation for acute myocardial infarction after percutaneous coronary intervention may be influenced by body mass index (BMI). Objectives To investigate the association BMI on outcomes 12 months in patients with who were initially treated aspirin plus ticagrelor 1 month, and to assess whether BMI-based switching from (active control strategy) clopidogrel (deescalation is associated individualized benefits. Design, Setting, Participants...
Backgrounds/Aims Discovery of new prognostic factors for cases in which the pancreatic cancer scoring and staging system does not result a clear definition is imperative. We examined role Human AlkB homolog H5 (ALKBH5) as marker cancer. Methods Patient data were extracted from International Cancer Genome Consortium (ICGC) The Atlas (TCGA). value ALKBH5 was confirmed via analysis other clinical factors, such age, sex, stage, using time-dependent area under curve (AUC) Uno's C-index, AUC...
A congenital adhesion band is a rare condition, but may induce small bowel obstruction (SBO) at any age. However, only few sporadic case reports exit. We aimed to identify the clinical characteristics of manifesting SBO stratified by age group between pediatric and adult patients. The medical records all patients with Jan 1, 2009 Dec 31, 2015 were retrospectively reviewed. Cases associated previous surgical procedure cases secondary due inflammatory processes or tumor other systemic diseases...
Preduodenal portal vein, a rare anomaly, could be found in any age groups. In pediatrics it may present with duodenal obstruction by itself or other coexisting anomalies; however usually an asymptomatic incidental findings during surgery adults. This anomaly has clinical importance due to the possibility of accidental damage vein. addition describing series 3 cases different manifestation infants, discuss about this review relevant literature.
Silicon (Si) nanostructures that exhibit a significantly low reflectance in ultraviolet (UV) and visible light wavelength regions are fabricated using hydrogen etching process. The Si have aperiodic subwavelength structures with pyramid-like morphologies. detailed morphologies of the can be controlled by changing condition. nanostructured exhibited much more reduced than flat surface: an average was approximately 6.8% region slight high 17% UV region. further both through deposition...
AIM:To determine the cytological and molecular effects of peroxisome proliferation-activated receptor (PPAR)-γ PPAR-γ agonists on stomach cancer cells. METHODS:To proliferation-suppressive troglitazone ciglitazone, SNU-216 SNU-668 cells were plated in media containing 40 µmol/L ciglitazone at a density 1 × 10 4 cells/well.After 3, 5 7 d, counted with hemocytometer.To assess appearance PPAR-γ, reverse-transcription polymerase chain reaction analysis was performed.On day 7, Western blotting...
Anodic aluminum oxide (AAO) films with different pore sizes were prepared to modulate the effective refractive index and birefringence. To investigate relationship between size of AAO film, optical constants obtained using a prism coupler various lasers. With experimental results, dispersion curve alumina itself without pores was extracted theoretical anisotropic model. We demonstrated that could offer wide range birefringence values for device applications. Furthermore, profiles as function...
Laparoscopic total extraperitoneal (TEP) repair of inguinal hernia is technically challenging enough to build high barrier entry. The purpose this study was identify clinical factors influencing technical difficulty with laparoscopic TEP according learning period.We conducted a retrospective 112 adult patients who underwent for unilateral from January 2009 September 2013. A difficult case defined as the 70th percentiles or more in distribution curve operative time, major complication, open...
We investigate the localized surface plasmon (LSP) effect by Al nanorings on AlGaN/GaN multiple quantum well (MQW) structure emitting at 365 nm. For this experiment, first, size of is optimized to maximize energy transfer (or coupling) between LSP and MQW using silica nanospheres. Then, with an outer diameter 385 nm, which exhibit a strong absorption peak in near-ultraviolet region, are applied top MQW. The photoluminescence (PL) intensity increased 227% 365 nm compared that without...
The growth of a high-quality In0.5Ga0.5P/GaAs heterostructure on (100) GaAs substrate by liquid-phase epitaxy is demonstrated. This has been achieved controlling the vaporizing time phosphorus after melt saturation procedure. photoluminescence spectra heteroepitaxial layers show that major residual acceptor impurity either carbon or silicon. measured values conduction-band discontinuity ΔEc and fixed interface charge density σi for are 110 meV 1×1011 cm−2, respectively. Only one electron...
An efficient quenching of the photoluminescence spectrum was observed for quantum dot (QD)-multiwalled carbon nanotubes (MWCNTs) nanocomposite. While lifetime blue emission from ZnSe shell significantly reduced, it did not exhibit any obvious change in red CdSe core-crystal. This difference revealed two competing charge transfer processes between core-crystal, and MWCNTs. Current-voltage measurements on devices fabricated utilizing QD-MWCNT nanocomposites showed photovoltaic (PV) effect...
Alimentary tract duplication (ATD) is a rare congenital condition that may occur throughout the intestinal tract. Clinical symptoms are generally related to involved site, size of duplication, or associated ectopic mucosa. This study aimed identify clinical implications by anatomical locations and age group then suggest relevant management according its distinct features.We retrospectively reviewed data pediatric patients who received surgical due ATD. Furthermore, including patients'...
Anorectal malformations are often associated with other anomalies, reporting frequency 40-70%. Gastrointestinal anomalies have been known to be relatively less common than of organ system. This study was performed assess a distinctive feature cases esophageal atresia.Clinical data (from January 2000 through December 2011) on the 196 subjects anorectal malformations, managed in our Hospital, were reviewed. Total 14 neonates identified accompanying atresia and retrospective analysis...
One of the major causes bowel obstruction in extremely premature infants is a meconium obstruction. However, there are many challenges not only recognition and diagnosis, but also management This study aimed to find perioperative clinical features determine postoperative course meconium-related ileus very low birth weight (VLBW) (ELBW) infants.We retrospectively reviewed data (n = 11, VLBW infnats; n 16, ELBW infants) with who underwent operation for intractable between January 2009 May...
Adult intestinal epithelial stem cells are a promising resource for treatment of disorders that cause failure and tissue engineering. We developed two different animal models to study the implantation cultured murine human in less differentiated "spheroid" state more "enteroid" into denuded small intestine mice. Engraftment donor could not be achieved while recipient remained continuity. However, we were able demonstrate successful when graft segment was bypassed loop jejunum. Implantation...
Cholecystectomy is rarely performed in the child and adolescent. However, it associated with several conditions. This study was conducted to describe characteristics of pediatric patient who underwent cholecystectomy unrelated hematologic disorders, then suggest its clinical significance management by comparing a simple complicated gallbladder disease.We reviewed cases patients (under 18 years old) at single institution between January 2003 October 2014. There were 143 during period 24...
Surgeons occasionally encounter a case of recurrent hernia in adult patients after the primary repair, and these cases are challenging to manage appropriately. This study was conducted describe clinical nature inguinal hernia, compare results management, identify relationship between specific risk factors occurrence hernia. Retrospectively reviewed 58 who underwent herniorrhaphy for single institution. Analyzed characteristics tried verify smoking, obesity, Recurrent 13.5 per cent all...