<h3>Objective</h3> Coeliac disease is defined by gluten responsiveness, yet there are few data on challenge (GC) in adults a gluten-free diet. Lack of regarding the kinetics responses to limitation clinical practice and research when GC performed. <h3>Design</h3> 20 with biopsy-proven coeliac participated. The study included two run-in visits followed 14-day at randomly assigned dose 3 or 7.5 g gluten/day. Study occurred 3, 7, 14 28 days after starting GC. Duodenal biopsy was performed...

Summary Background Coeliac disease is increasingly diagnosed and weight changes are common after adoption of a gluten‐free diet ( GFD ), however data on body mass index BMI ) limited. Aim To assess in diagnosis large coeliac population. Methods A total 1018 patients with biopsy confirmed seen at our centre were studied retrospectively. Initial follow‐up s recorded, as was adherence assessed by an expert dietitian. Results 679 least two recorded included the study. Mean 39.5 months. Compared...

Probiotics are believed to be beneficial in maintaining a healthy gut microbiota whereas antibiotics known induce dysbiosis. This study aimed examine the effects of probiotic Saccharomyces boulardii CNCM I-745 (SB), antibiotic Amoxicillin-Clavulanate (AC) and combination on symptoms humans.Healthy subjects were randomized one 4 groups: SB for 14 days, AC 7 plus AC, Control (no treatment). Participants gave stool samples completed gastro-intestinal symptom questionnaires. Microbiota changes...

Summary Background Duodenal villous atrophy (DVA) is a key diagnostic finding in coeliac disease (CD). However, the differential diagnosis for this broad. Aim To identify conditions causing noncoeliac enteropathy (NCE) with and methods to differentiate between CD NCE clinical practice. Methods Through record review we identified patients DVA due other than CD. Patient demographics, features relevant investigations were compared patients. Rates of misdiagnosis, response treatments recorded....

OBJECTIVES: Differentiating between celiac disease (CD) and non-celiac gluten sensitivity (NCGS) is important for appropriate management but often challenging. METHODS: We retrospectively reviewed records from 238 patients who presented the evaluation of symptoms responsive to restriction without prior diagnosis or exclusion CD. Demographics, presenting symptoms, serologic, genetic, histologic data, nutrient deficiencies, personal history autoimmune diseases, family CD were recorded. NCGS...

Background Interactions between the microbial flora of intestine and human host play a critical role in maintaining intestinal health pathophysiology wide variety disorders such as antibiotic associated diarrhea, Clostridium difficile infection, inflammatory bowel disease. Prebiotics can confer benefits by beneficial effects on microbiome, whereas antibiotics disrupt microbiome leading to diarrhea other side effects.Aim To compare prebiotic, polysaccharopeptide from Trametes versicolor,...

Multiple European studies report increased prevalence of selective immunoglobulin A deficiency (SIgAD) and partial (PIgAD) in patients with celiac disease (CD). However; prospective data representing North American adults are lacking. While SIgAD precludes the use IgA-tissue-transglutaminase antibody (IgA-tTG), effect PIgAD on IgA-tTG sensitivity is not well documented. We aim to determine impact IgA CD presentation diagnosis adult patients.We reviewed 1000 consecutive undergoing testing 243...

A BSTRACT Introduction: The Meso-Rex bypass (MRB) provides a physiological cure for EHPVO by restoring hepatopetal flow, effectively reducing portal pressure. We share our experience with the MRB procedure, its outcomes, and challenges. Aim: To describe feasibility effectiveness of in children practice. Materials Methods: This is retrospective study who underwent between January 2013 May 2024. was considered patients asymptomatic splenomegaly, moderate hypersplenism, patent left vein either...

Background: There are little data on patient factors that impact diagnosis rates of celiac disease. This study aims to evaluate the association between socioeconomic status and symptoms at Methods: A total 872 patients with biopsy-proven disease were categorized based presence or absence (1) diarrhea (2) any gastrointestinal diagnosis. Univariate multivariate analyses used assess symptoms. Results: Patients without presentation had a higher mean per capita income (US$34,469 versus US$32,237,...

This paper deals with the estimation of spectral acceleration for Manipur based on probabilistic seismic hazard analysis (PSHA). The 500 km region surrounding is divided into seven tectonic zones and major faults located in these are used to estimate hazard. earthquake recurrence relations have been estimated from past seismicity data. Ground motion prediction equations proposed by Boore Atkinson (2008 Earthq. Spectra24 99–138) shallow active regions (2003 Bull. Seismol. Soc. Am.93 1703–29)...

Saccharomyces boulardii CNCM I-745 (SB) is a probiotic yeast used to lower the incidence of antibiotic-associated Clostridium difficile (C. difficile) infection, though its mechanism action remains unclear. Cholic acid primary bile acid, which triggers germination and promotes growth C. difficile. The intestinal microbiota transforms into secondary acids. This study examined 1) antimicrobial-induced alteration fecal content, 2) whether concomitant administration SB influences this...

Micro-electro-discharge machining (micro-EDM) is a well-established micromanufacturing process and has been at the center of research for last few decades. However, it its own limitations. The limitations are primarily due to requirement tool electric potential between workpiece. laser induced plasma micromachining (LIP-MM) novel tool-less multimaterial selective material removal type process. In manner similar micro-EDM, also removes through plasma-matter interaction. instead potential,...

To identify the predictors of vitamin D deficiency in patients with and without inflammatory bowel disease (IBD).Patients ulcerative colitis (UC) or Crohn's (CD) related diagnostic codes who received medical care at University Mississippi Medical Center between July 2012 2015 were identified. After thorough chart review, we identified biopsy proven IBD had also been tested for serum 25-hydroxyvitamin [25(OH)D] concentration. We compared these to a previously studied cohort healthy controls...

Laser-induced plasma micromachining (LIP-MM) is a novel multimaterial and tool-less process. It utilizes tightly focused ultrashort laser irradiation to generate through laser-induced dielectric breakdown in material. The facilitates material removal plasma–matter interaction spot vaporization ablation. paper introduces the LIP-MM process, discusses underlying principles behind generation machining, proves its feasibility by describing experimental conditions under which machining occur....

The ultrashort pulsed laser ablation process is a well-established micromachining and has been at the center of manufacturing research in past decade. However, it its own limitations, primarily due to involvement various material-specific machining parameters. laser-induced plasma (LIP-MM) novel tool-less multimaterial selective material removal type process. In manner similar ablation, also removes through an beam. instead direct laser–matter interaction, uses beam generate within...

Introduction: We aimed to assess the impact of socio-economic determinants health (SEDH) on survival disparities within and between ethnic groups young-onset (&lt;50 years age) colorectal adenocarcinoma patients. Patients Methods: Surveillance, epidemiology, end results (SEER) registry was used identify patients aged 25–49 from 2012 2016. Survival analysis performed using Kaplan–Meir method. Cox proportional hazards model determine hazard effect SEDH. American community survey (ACS) data...

A new micro-machining process that is motivated by the need to overcome various limitations associated with micro-EDM (μ-EDM) introduced. The in μ-EDM are primarily due requirement of a conductive electrode and workpiece, tool wear, complex wear compensation strategies. process, termed “laser-induced plasma micro-machining” uses laser beam generate dielectric near workpiece surface whose explosive expansion results material removal mechanisms similar those occur μ-EDM.