A5100362102- Autophagy in Disease and Therapy
- Calcium signaling and nucleotide metabolism
- Cardiac, Anesthesia and Surgical Outcomes
- Heme Oxygenase-1 and Carbon Monoxide
- Power Line Communications and Noise
- Endoplasmic Reticulum Stress and Disease
- Adenosine and Purinergic Signaling
- Pancreatic function and diabetes
- Sirtuins and Resveratrol in Medicine
- Intensive Care Unit Cognitive Disorders
- CRISPR and Genetic Engineering
- Calpain Protease Function and Regulation
- Anesthesia and Sedative Agents
- Advanced Glycation End Products research
Anhui Medical University
2024
Soochow University
2009-2024
First Affiliated Hospital of Anhui Medical University
2024
Shandong Academy of Agricultural Sciences
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
Guang’anmen Hospital
2019
Gladstone Institutes
2015
Advanced glycation end-products (AGEs) contribute to the pathogenesis of diabetes mellitus and atherosclerosis by promoting vascular endothelial cell proliferation, migration, damage death. In this study, we examined role autophagy in HUVECs exposed AGE-modified bovine serum albumin (AGE-BSA). incubated with AGE-BSA for 6 h showed an increase formation acidic vesicular organelles autophagosomes. AGE-BSA-induced upregulation microtubule associated protein 1 light chain 3-II (LC3-II), a marker...
Abstract Background Previous study reported that resveratrol has anti-tumor activity. In this study, we investigated the involvement of autophagy in resveratrol-induced apoptotic death human U251 glioma cells. Methods The growth inhibition cells induced by was assessed with methyl thiazolyl tetrazolium (MTT). activation and proapoptotic effect were characterized monodansylcadaverine labeling Hoechst stain, respectively. Mitochondrialtransmembrane potential (ΔΨm) measured as a function drug...
Abstract Background Oxidative stress is an important pathogenic factor in influenza A virus infection. It has been found that reactive oxygen species induced by the H9N2 associated with viral replication. However, mechanisms involved remain to be elucidated. Methods In this study, role of autophagy was investigated virus-induced oxidative and replication A549 cells. Autophagy inhibited inhibitor or RNA interference, level, presence were detected western blot, TCID50 assay, Real-time PCR....