A5021336689- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Allergic Rhinitis and Sensitization
- Corneal Surgery and Treatments
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Ocular Infections and Treatments
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Retinal Development and Disorders
- Intraocular Surgery and Lenses
- Ocular Oncology and Treatments
- Facial Rejuvenation and Surgery Techniques
- Urticaria and Related Conditions
- Olfactory and Sensory Function Studies
- Skin Protection and Aging
- Salivary Gland Disorders and Functions
- melanin and skin pigmentation
- Meningioma and schwannoma management
- Dermatology and Skin Diseases
- Retinopathy of Prematurity Studies
University of Milan
2016-2025
MultiMedica
2015-2025
Ospedale San Giuseppe
2013-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2008-2024
Weatherford College
2021
Massachusetts Eye and Ear Infirmary
2020
Smith-Kettlewell Eye Research Institute
2020
Ocular Surface Center
2020
Tear Film & Ocular Surface Society
2020
UNSW Sydney
2020
To analyze the in vivo morphology of corneal cells and nerves dry eye associated with primary (SSI) secondary (SSII) Sjögren's syndrome to study its relationship clinical evaluation.Thirty-five patients SS 20 age- gender-matched control subjects were studied. Confocal microscopy was used investigate thickness, epithelial stromal cellular density, subbasal plexus morphology.Corneal central thickness 514.74 +/- 19.85 microm group 550 21.46 (P < 0.0001, t-test); 456.62 18.05 487.35 20.40...
To analyze the in vivo morphology of corneal cells and nerves patients with rheumatoid arthritis (RA), or without secondary Sjögren's syndrome (SSII), to investigate correlations between alterations RA activity.Fifty 30 age- gender-matched control subjects were studied. SSII was diagnosed according American-European Consensus Group criteria, activity evaluated by Lansbury index (LI). Confocal microscopy used thickness, number epithelial stromal cells, keratocyte hyperreflectivity. In...
Purpose To study, by a new, integrated, laser scanning confocal microscopy approach, the ocular surface morpho-functional unit in patients with primary Sjogren syndrome (SSI), non–Sjogren dry eye (non-SSDE), and meibomian gland disease (MGD). Methods Patients age- sex-matched control subjects (N = 60; 15 each) were consecutively enrolled prospective case-control study. Laser was used to obtain simultaneous optical sampling of components: cornea, bulbar tarsal conjunctiva, MGs, eyelid margin....
To assess and compare early modifications in inner retinal layer thickness optical coherence tomography angiography parameters patients with diabetes mellitus (DM) Types 1 2 without clinical signs of diabetic retinopathy.Ninety eyes 90 subjects (24 Type DM, 36 30 healthy controls) were prospectively evaluated spectral domain OCT, swept-source OCT angiography, color fundus photography (on the same day). Retinal nerve fiber layer, ganglion cell (GCL+), + GCL+ (GCL++) automatically determined...
Purpose: To evaluate peripapillary vessel density and morphology in patients with diabetes mellitus (DM) without clinical signs of diabetic retinopathy (DR) mild, nonproliferative DR to correlate nerve fiber layer (NFL) thickness. Methods: One hundred seventeen eyes (34 healthy controls, 54 DM [noDR group] 24 mild [DR group]) were prospectively evaluated. All subjects underwent macular optical coherence tomography angiography (OCT-A). Peripapillary NFL thickness was also recorded. OCT-A slab...
Efron, N., Jones, L., Bron, A. J., Knop, E., Arita, R., Barabino, S., … Markoulli, M. (2013). The TFOS International Workshop on Contact Lens Discomfort: Report of the Interactions With Ocular Surface and Adnexa Subcommittee. Investigative Opthalmology & Visual Science, 54(11), TFOS98. https://doi.org/10.1167/iovs.13-13187
To evaluate the efficacy and safety of atropine 0.01% in slowing myopia progression European paediatric patients.Retrospective, medical records review study. Medical charts patients with a > 0.5 D/year treated for at least 1 year were included. Patients receive complete ophthalmic examination before 12 months after initiation treatment. A group myopic untreated children serves as control group. The rate baseline treatment was evaluated. also compared. Adverse events recorded.Medical 52 50...
To study the clinical involvement of ocular surface and in vivo morphology corneal cells nerves, patients affected by active inactive Graves' orbitopathy (GO).The included 26 consecutive GO 20 age- sex-matched healthy control subjects. was diagnosed on basis criteria European Group Orbitopathy, disease activity evaluated Clinical Activity Score (CAS). Each participant underwent a full eye examination, including an evaluation symptoms (Ocular Surface Disease Index score), tear break-up time,...
Purpose.: To evaluate morphologic changes in meibomian glands (MGs) and the status of periglandular inflammation patients with primary secondary Sjögren's Syndrome (SS) using vivo confocal laser microscopy (LSCM). Methods.: Twenty SS (SSI), 25 (SSII), 20 MG dysfunction (MGD), age- gender-matched control subjects were enrolled consecutively. Each participant completed an Ocular Surface Disease Index questionnaire underwent a full eye examination, including tear film break-up time (BUT),...
To evaluate by in vivo laser scanning confocal microscopy (LSCM) the morphologic changes meibomian glands (MGs) and status of periglandular inflammation contact lens wearers (CLWs) to investigate correlations between clinical findings.Twenty CLWs 20 age- sex-matched control subjects were consecutively enrolled. Each participant completed an Ocular Surface Disease Index questionnaire underwent a full eye examination, including tear film break-up time, fluorescein lissamine green staining,...
Recent success in clinical trials supports the use of adeno-associated viral (AAV) vectors for gene therapy retinal diseases caused by defects pigment epithelium (RPE). In contrast, evidence efficacy AAV-mediated transfer to photoreceptors, major site inherited diseases, is less robust. addition, although RPE transduction appears efficient, independently serotype used and species treated, photoreceptor has not been systematically investigated thus so far large animal models, which also may...
To evaluate, by in vivo laser scanning confocal microscopy (LSCM), the corneal findings moderate-to-severe dry eye patients before and after treatment with topical corticosteroid to associate clinical response.Fifty eyes of 50 were included this open-label, masked study. Exclusion criteria any systemic or ocular condition (other than eye) (except artificial tears), ongoing performed previous 3 months, known effect on surface. All treated loteprednol etabonate ophthalmic suspension 0.5% qid...
Optical coherence tomography angiography (OCT-A) has recently improved the ability to detect subclinical and early clinically visible microvascular changes occurring in patients with diabetes mellitus (DM). The aim of present study is evaluate compare quantitative macular perfusion parameters DM without DR mild nonproliferative (NPDR) evaluated by two different swept-source (SS) OCT-A instruments using scan protocols (3 × 3 mm 6 mm). One hundred eleven subjects/eyes were prospectively...
To evaluate age-related Meibomian gland (MG) changes by in vivo laser scanning confocal microscopy (LSCM).Asymptomatic healthy subjects (n=100, age range 20-83 years) with an Ocular Surface Disease Index score of less than 13 were consecutively enrolled. Two additional groups, one composed under 40 years (n=12) and over 65 (n=12), included without inclusion or exclusion criteria. All underwent a full ocular surface evaluation, eye each subject was examined LSCM to quantify the lower lid MG...
The purpose of this research was to study ocular surface inflammation in relation systemic disease activity rheumatoid arthritis (RA) patients with or without secondary Sjögren's syndrome (SSII and non-SSII respectively). conducted two phases. In phase I, 12 active RA SSII were consecutively enrolled. Each completed an Ocular Surface Disease Index (OSDI) questionnaire underwent a full eye exam vivo confocal microscopy examination the cornea. Tear fluid samples collected sponges analyzed for...