A5075386227- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced ceramic materials synthesis
- Gold and Silver Nanoparticles Synthesis and Applications
- Spectroscopy and Chemometric Analyses
- Catalytic Processes in Materials Science
- Bone Tissue Engineering Materials
- Advanced materials and composites
- Dental materials and restorations
- Dental Implant Techniques and Outcomes
- Advanced biosensing and bioanalysis techniques
- Glass properties and applications
- Nuclear materials and radiation effects
- Biosensors and Analytical Detection
- Catalysis and Oxidation Reactions
- Bee Products Chemical Analysis
- Ferroelectric and Piezoelectric Materials
- Semiconductor materials and devices
- Advanced Chemical Sensor Technologies
- Thermography and Photoacoustic Techniques
- Silymarin and Mushroom Poisoning
- Force Microscopy Techniques and Applications
- Quantum Dots Synthesis And Properties
- Aluminum Alloys Composites Properties
- Ultrasonics and Acoustic Wave Propagation
- Chalcogenide Semiconductor Thin Films
University of Trieste
2015-2024
University of Macau
2018-2022
Engineering (Italy)
2020
Universitat de Barcelona
2005
National Interuniversity Consortium of Materials Science and Technology
2004
Sapienza University of Rome
1999-2001
Istituto Nazionale di Fisica Nucleare, Sezione di Roma I
1999
University of California, Santa Barbara
1995-1998
American Ceramic Society
1993-1998
Istituto Officina dei Materiali
1997-1998
The objective of the article is to review biomedical applications which became possible after development sensitive and high throughput Raman Fourier transform infrared spectrometers in past decade. Technical aspects instrumentation are briefly described. Then broad range vibrational spectroscopic with focus on imaging fiber‐optical methods discussed study mineralized tissue (bone, teeth), skin, brain, gastrointestinal tract (mouth, pharynx, esophagus, colon), breast, arteries, cartilage,...
Raman mapping in combination with uni- and multi-variate methods of data analysis is applied to articular cartilage samples. Main differences biochemical composition collagen fibers orientation between superficial, middle deep zone the tissue are readily observed Collagen, non-collagenous proteins, proteoglycans nucleic acids can be distinguished on basis their different spectral characteristics, relative abundance mapped label-free samples, at so high a resolution as permit level single...
Abstract Forty years ago, Garvie and his Australian co‐workers reported that the stress‐induced transformation of metastable tetragonal zirconia grains to monoclinic symmetry could give rise a powerful toughening mechanism. Their results even led them consider systems as analogues certain steels. This seminal paper generated extraordinary excitement in ceramic community it is still subject extensive research. Transformation widely used materials an increase strength toughness when compared...
Surface-enhanced Raman scattering (SERS) is a powerful and sensitive technique for the detection of fingerprint signals molecules investigation series surface chemical reactions. Many studies introduced quantitative applications SERS in various fields, several methods have been implemented each specific application, ranging performance characteristics, analytes used, instruments, analytical matrices. In general, very few validated according to international guidelines. As consequence,...
Colon tissue constitutes a valid model for the comparative analysis of soft by Raman and Fourier transform infrared (FTIR) imaging because it contains four major types such as muscle tissue, connective epithelium nerve cells. microscopic images were recorded in mapping mode using 785 nm laser excitation step size 10 microm from three regions within thin section that encompassed mucus, mucosa, submucosa, longitudinal circular layers. FTIR composed 4, 8 9 individual 4096 spectra each same...
Positively charged nanoparticles to be used as substrates for surface-enhanced Raman scattering (SERS) were prepared by coating citrate-reduced silver with the cationic polymer poly-l-lysine. The average diameter of coated is 75 nm, and their zeta potential +62.3 ± 1.7 mV. UV-vis spectrophotometry dynamic light measurements show that no aggregation occurs during process. As an example application, so-obtained positively particles employed detect nanomolar concentrations anionic chromophore...
Silver-coated porous silicon and polydimethylsiloxane (PDMS) are systematically analyzed as substrates for surface-enhanced Raman scattering (SERS). They were selected representative metal–dielectric nanostructures characterized by different morphology substrate dielectric constant which is reflected in the electromagnetic near-field intensity spectra. The study conducted using 4-mercaptobenzoic acid probe molecule with aim to compare efficiency homogeneity of signal on substrates. A larger...
Therapeutic drug monitoring (TDM) for anticancer imatinib has been suggested as the best way to improve treatment response and minimize risk of adverse reactions in chronic myelogenous leukemia (CML) gastrointestinal stromal tumor (GIST) patients. TDM oncology treatments with standard analytical methods, such liquid chromatography–tandem mass spectrometry (LC–MS/MS) is, however, complex demanding. This paper proposes a new method quantitation human plasma, based on surface enhanced raman...
The variable configuration of Raman spectroscopic platforms is one the major obstacles in establishing spectroscopy as a valuable physicochemical method within real-world scenarios such clinical diagnostics. For real world applications like diagnostic classification, models should ideally be usable to predict data from different setups. Whether it done by training rugged model with many setups or primary-replica strategy where are developed on 'primary' setup and test generated 'replicate'...
Observations are reported of the room‐temperature propagation a spalling failure mode thermal barrier coating (TBC) from its bond coat after oxidation. The is Y 2 O 3 ‐stabilized ZrO formed by electron‐beam deposition on Ni‐Co‐Cr‐Al‐Y coat. spall shape evolution and stress redistribution as propagates reported. primarily an interface crack between thermally grown aluminum oxide (TGO) underside TBC during observations consistent with subcritical TGO assisted presence moisture. An estimate 9...
To date, in spite of their toxicity, the plasmatic concentration most chemotherapeutic drugs is difficult to monitor oncological patients, because quantitative determination expensive and time consuming. This contribution reports a first attempt for direct drug human serum samples by means Surface Enhanced Raman Spectroscopy (SERS). In this study, SERS substrates constituted Au nanoparticles deposited on paper simple dipping method have been used rapid (few minutes) analysis diluted spiked...