A5008270635- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- RNA and protein synthesis mechanisms
- Helicobacter pylori-related gastroenterology studies
- Plant Micronutrient Interactions and Effects
- Ethnobotanical and Medicinal Plants Studies
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Monoclonal and Polyclonal Antibodies Research
- vaccines and immunoinformatics approaches
Huazhong Agricultural University
2017-2023
Ahmadu Bello University
2015-2018
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each year. The eradication of Mycobacterium tuberculosis, the main causative agent TB, increasingly challenging due to emergence extensive drug-resistant strains. Vaccination considered an effective way protect host from pathogens, but only clinically approved TB vaccine, Bacillus Calmette-Guérin (BCG), has limited protection in adults. Multi-epitope vaccines have been found enhance immunity diseases by...
The nonpathogenic bacterium Mycobacterium smegmatis mc2155 has been widely used as a model organism in mycobacterial research, yet detailed study about its transcription landscape remains to be established. Here we report the transcriptome, expression profiles and transcriptional structures through growth-phase-dependent RNA sequencing (RNA-seq) well other related experiments. We found: 1) 2139 start sites (TSSs) genome-wide scale, of which eight samples were randomly selected further...
Inflammation has been implicated in many disorders, including cancer and available therapies elicit adverse effects. Plants of the family Rubiaceae have shown potency against inflammation. The anti-inflammatory anti-oxidant potential Feretia apodanthera was investigated this study to evaluate its effectiveness.The phytochemical, antioxidant root bark (n-Hexane, diethyl ether, ethanol aqueous) extracts study. were subjected various chemical tests for phytochemical constituents; their activity...
Under starvation conditions, bacteria tend to slow down their translation rate by reducing rRNA synthesis, but the way they accomplish that may vary in different bacteria. In Mycobacterium species, transcription of is activated RNA polymerase (RNAP) accessory factor CarD, which interacts directly with RNAP stabilize RNAP-promoter open complex formed on genes. The functions CarD have been extensively studied, mechanisms control its expression remain obscure. Here, we report level was tightly...
Abstract Under starvation conditions, bacteria tend to slow down their translation rate by reducing rRNA synthesis, but the way they accomplish that may vary in different bacteria. In Mycobacterium species, transcription of is activated RNA polymerase (RNAP) accessory factor CarD, which interacts directly with RNAP stabilize RNAP-promoter open complex formed on genes. The functions CarD have been extensively studied, mechanisms control its expression remain obscure. Here, we report level was...
The effect of 10% supplementation fermented and unfermented Telfaira occidentalis Gnetum africanum leaves for 21 days on haemoglobin-iron, haematological parameters serum ferritin was investigated to determined if the could replenish haemoglobin in iron deficient rats. Iron deficiency significantly (p<0.05) decreased relative weight gain, ferritin, (Hb), mean corpuscular concentration (MCHC), when compared sufficient control Rats fed with T. had a increased those G. leaves. levels rats...