A5063181399- Wound Healing and Treatments
- Cutaneous lymphoproliferative disorders research
- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Dermatologic Treatments and Research
- Electrochemical sensors and biosensors
- Hair Growth and Disorders
- Autoimmune Bullous Skin Diseases
- Pressure Ulcer Prevention and Management
- Urticaria and Related Conditions
- Skin Diseases and Diabetes
- Autoimmune and Inflammatory Disorders
- Analytical Chemistry and Sensors
- Chemotherapy-related skin toxicity
- melanin and skin pigmentation
- Vasculitis and related conditions
- Renal Transplantation Outcomes and Treatments
- Tumors and Oncological Cases
- Surgical Sutures and Adhesives
- Renal Diseases and Glomerulopathies
- Skin and Cellular Biology Research
- Diagnosis and Treatment of Venous Diseases
- Dupuytren's Contracture and Treatments
- Osteomyelitis and Bone Disorders Research
- Acne and Rosacea Treatments and Effects
Larkin Community Hospital
2022-2024
Florida Academic Dermatology Center
2024
Palm Springs General Hospital
2024
University Hospital of Zurich
2024
University of Miami
2017-2023
Lake Erie College of Osteopathic Medicine
2023
University Hospital of Basel
2022
Wound management involves repeated clinical trips and procedures of lab tests over days. To eliminate this time lag provide real-time monitoring a wound's progress, we have designed an enzymatic biosensor for determining uric acid (UA) in wound fluid. Uric Acid is biomarker, having established correlation with wounds their healing. This electrochemical comprises enzyme urate oxidase (uricase, UOx) entrapped polyvinyl alcohol based cationic polymer enhanced stability. Results show that the...
Fibrosis can develop in nearly any tissue leading to a wide range of chronic fibrotic diseases. However, current treatment options are limited. In this study, we utilized an established aged mouse model bleomycin-induced lung fibrosis (BLM) test our hypothesis that may simultaneously multiple organs by evaluating skin and wound healing. was induced (18-22-month-old) C57BL/6 male mice intratracheal BLM administration. Allogeneic adipose-derived mesenchymal stromal cells (ASCs) or saline were...
This work reports a bi-enzymatic biosensor for monitoring uric acid (UA) in biofluids extracted from wound, perilesional skin and healthy skin. The is composed of uricase (UOx) as biocatalyst UA oxidation, horseradish peroxidase (HRP) electron transfer nanocomposite multi-walled carbon nanotubes (MWCNTs) Au nanoparticles (AuNPs) the substrate. approach provided two-fold enhancement current response, while facilitated higher enzyme loading fast enabling 2-fold increase response. was able to...
Background: Despite the development of numerous wound treatment alternatives, 25% to 50% leg ulcers and >30% foot are not fully healed after 6 months treatment. Autologous skin grafting is a time-tested therapy for these wounds; however, creation new in donor area yields considerable limitation this procedure. Innovation: Fractional autologous full-thickness (FFTSG) technique wherein multiple small grafts (FTSGs) harvested with possibly minor donor-site comorbidities. The first device used...
Wound area measurements provide an objective assessment of wound healing; however, most commonly used measurement techniques are imprecise.A new portable 3-dimensional (3D) device was tested against laser- and hand-measurement methods.A retrospective comparative analysis conducted to analyze the difference in using records patients seen at University Miami Hospital (Miami, FL) outpatient healing clinic between November 2017 February 2018 who had wounds various etiologies measured 3 different...
This work reports a biosensor for monitoring xanthine potential wound healing assessment. Active substrate of the has oxidase (XO) and horseradish peroxidase (HRP) physisorbed on nanocomposite multiwalled carbon nanotubes (MWCNT) decorated with gold nanoparticles (AuNP). The presence HRP provided two-fold increase in response to xanthine, three-fold nanocomposite. With sensitivity 155.71 nA μM−1 cm−2 offers detection limit 1.3 μM, linear between 22 μM 0.4 mM. Clinical sample analyses showed...
Among hospital-acquired infections, surgical site infections (SSIs) are frequent. SSI in the early post-transplant course poses a relevant threat to transplant recipients.To determine incidence, risk factors for and its association with outcomes pancreas (P-Tx) recipients.Adult simultaneous kidney-pancreas transplantation (SPK-T) P-Tx recipients follow-up of at least 90 days were identified Swiss Transplant Cohort Study (STCS) dataset. Except categorization SSIs according Centers Disease...
Abstract Mycobacterium avium‐intracellulare (MAC) infection may have different skin manifestations, including cutaneous granulomas. Granulomatous reactions distinct morphologic and histopathologic appearances. We present the case of an adolescent male with MAC, misdiagnosed as sarcoidosis after initial biopsy results, demonstrated preservation reticulin fibers absence organisms within Sarcoidal granulomas often stain positive for fibers, which could be used to distinguish them from...
Infectious diseases (IDs) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes death. Patients undergoing kidney retransplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period, potentially facilitating subsequent infections. Comparing ID events re-K-Tx first (f-K-Tx) can delineate patterns risks associated with immunosuppression.
Background: Chronic wounds remain a challenge for the clinician and healthcare system. It is therefore vital additional therapies that target steps involved in wound recalcitrance. Recently, topical timolol has shown promising results use healing. Objective: The goal of this study was to assess timolol’s effectiveness healing varying etiologies. Methods: This multi-center series took place from 2016¬–2019 at centers University Miami Health System Veterans Affairs Northern California...
Frontal fibrosing alopecia (FFA) is a scarring affecting mainly postmenopausal females. Associated clinical signs include facial papules, glabellar red dots, depression of frontal veins, and lichen planus pigmentosus. Our objective was to establish the validity increased preauricular lines as another marker FFA.Thirty-two females with FFA were compared 32 age-matched either androgenetic or chronic telogen effluvium. Bilateral images area taken, disease severity calculated in all patients...