Kanjana Changkaew

ORCID: 0000-0003-3883-3430
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About
Contact & Profiles
Research Areas
  • Antibiotic Resistance in Bacteria
  • Salmonella and Campylobacter epidemiology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bacteriophages and microbial interactions
  • Antimicrobial Resistance in Staphylococcus
  • Indoor Air Quality and Microbial Exposure
  • Genomics and Phylogenetic Studies
  • Bacterial Genetics and Biotechnology
  • Infection Control and Ventilation
  • Bacterial biofilms and quorum sensing
  • Aquaculture disease management and microbiota
  • Veterinary medicine and infectious diseases
  • Identification and Quantification in Food
  • Escherichia coli research studies
  • Vibrio bacteria research studies
  • Microbial Metabolism and Applications
  • Fecal contamination and water quality
  • Bacterial Identification and Susceptibility Testing

Thammasat University
2017-2025

Faculty of Public Health
2020

Hokkaido University
2014-2016

ABSTRACT The study aimed to evaluate the antimicrobial resistance (AMR) patterns among fecal indicator bacteria and analyze characteristics of wastewater from anaerobic digestion (AD) treatment systems in swine farms. Escherichia coli Enterococcus spp. were identified by conventional molecular methods. AMR profiles quality analyzed using standard results indicated that primary resistances observed E. against AM, TE, SXT, DO. Among spp., highest was noted for followed E, CIP, NX. faecium...

10.2166/wh.2025.323 article EN cc-by Journal of Water and Health 2025-03-01

Methicillin-resistant Staphylococcus aureus (MRSA) have been a major public health concern in humans. Among MRSA, livestock-associated (LA)-MRSA strains always associated with exposure to livestock or their products and emerged different countries globally. Although studies identified LA-MRSA from healthy pigs pork Thailand, prevalence slaughtered is still unknown. In addition, there are few reports on the epidemiology molecular characteristics of Thailand. Hence, this first report...

10.3390/antibiotics10020206 article EN cc-by Antibiotics 2021-02-19

Amino acid substitutions providing quinolone resistance to Campyloabcter jejuni have been found in the resistance-determining region of protein DNA gyrase subunit A (GyrA), with highest frequency at position 86 followed by 90. In this study, wild-type and mutant recombinant subunits were expressed Escherichia coli purified using Ni-NTA agarose column chromatography. Soluble 97 kDa GyrA 87 B shown reconstitute ATP-dependent supercoiling activity. quinolone-inhibited assay demonstrated roles...

10.1002/dta.1937 article EN Drug Testing and Analysis 2016-02-09

Salmonella Enteritidis has emerged as a global concern regarding quinolone resistance and invasive potential. Although quinolone-resistant S. been observed with high frequency in Thailand, information on the mechanism of acquisition is limited. To elucidate mechanism, total 158 clinical isolates nalidixic acid (NAL)-resistant were collected throughout determinants investigated context levels to NAL, norfloxacin (NOR), ciprofloxacin (CIP). The analysis point mutations type II topoisomerase...

10.1089/mdr.2015.0234 article EN Microbial Drug Resistance 2017-02-23

The prevalence of quinolone-resistant Salmonella has become a public health concern. Amino acid substitutions have generally been found within the quinolone resistance-determining region in subunit A DNA gyrase (GyrA) Typhimurium. However, direct evidence contribution these to resistance remains be shown. To investigate significance amino S. Typhimurium GyrA resistance, we expressed recombinant wild-type (WT) and five mutant gyrases Escherichia coli characterized them vitro. WT were...

10.1002/dta.1910 article EN Drug Testing and Analysis 2015-10-30

Staphylococcus haemolyticus 010503B is a multidrug-resistant bacterium isolated from an outpatient clinic in hospital waiting area Thailand. Here we present the draft genome sequence of S. 010503B. The paired-end reads were generated on Illumina NextSeq 550 sequencer using genomic DNA pure culture consisted 114 contigs with total size 2,457,654 base pairs, N50 57,312 pairs and GC content 32.60%. dDDH between SM 131T was 91.9%, identifying strain as haemolyticus. data presented holds promise...

10.1016/j.dib.2024.110154 article EN cc-by Data in Brief 2024-02-06
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