A5063852105- Traditional and Medicinal Uses of Annonaceae
- Ginger and Zingiberaceae research
- Phytochemistry and Biological Activities
- Bioactive Natural Diterpenoids Research
- Natural product bioactivities and synthesis
- Advanced Synthetic Organic Chemistry
- Crystallization and Solubility Studies
- Magnolia and Illicium research
- NF-κB Signaling Pathways
- Pharmacological Effects of Natural Compounds
- Plant biochemistry and biosynthesis
- Plant-derived Lignans Synthesis and Bioactivity
- Phytochemistry and Bioactivity Studies
- X-ray Diffraction in Crystallography
- Phytochemical compounds biological activities
- Synthetic Organic Chemistry Methods
- Computational Drug Discovery Methods
- Nanoplatforms for cancer theranostics
- Piperaceae Chemical and Biological Studies
- Phytochemistry and Bioactive Compounds
- Phagocytosis and Immune Regulation
- Eicosanoids and Hypertension Pharmacology
- Vitamin C and Antioxidants Research
- Plant chemical constituents analysis
- Sphingolipid Metabolism and Signaling
Yangzhou University
2017-2024
State Administration of Traditional Chinese Medicine of the People's Republic of China
2018-2024
China Pharmaceutical University
2011-2017
// Shuna Cui 1, 2, 3, * , Juan Wang Qingqing Wu 1 Jing Qian 2 Changshui Yang Ping Bo Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention Treatment Senile Diseases, Medical College Yangzhou University, Yangzhou, China Department Gynaecology And Obstetrics Affiliated Hospital 3 Co-Innovation Center Control Important Animal Infectious Diseases Zoonoses, The authors have contributed equally in this work Correspondence to: Cui, email: sncui@yzu.edu.cn...
Abstract: Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn 2+ -coordinated doxorubicin (DOX)-loaded poly(lactic- co -glycolic acid) (PLGA) nanoparticles as platform synergistic chemo-photothermal tumor DOX-loaded PLGA (DOX/PLGA) were first synthesized through double emulsion-solvent evaporation method, and then modified with...
Two rearranged norditerpenoids with novel tricyclic carbon skeletons, strophiofimbrin A (1) and B (2), were isolated from Strophioblachia fimbricalyx. Their structures established by 1D/2D NMR spectroscopy, HRESIMS, quantum chemistry calculations, X-ray diffraction analyses. 1 2 represented the first examples of diterpenoids unprecedented 5/6/7-fused ring systems. In proposed biosynthetic pathway, they suspected to derive cleistanthane via opening, expansion, cyclization, rearrangement based...
An unusual katsumadain dimer via a [2 + 2] cycloaddition, C (1), and unique chalcone-diarylheptanoid adduct Diels–Alder reaction, calyxin Y (2) with novel carbon frameworks, were isolated from the seeds of Alpinia katsumadai. Their structures relative configurations determined by spectroscopic evidence.
5-Fluorouracil (5-FU) is a common anti-tumor drug, but there no effective treatment for its side effect, intestinal mucositis. The inflammatory reaction of macrophages in mucosa induced by 5-FU an important cause In this study, we investigated the anti-inflammatory effects three short-chain fatty acids (SCFAs), including sodium acetate (NaAc), propionate (NaPc), and butyrate (NaB), on human mononuclear macrophage-derived THP-1 cells 5-FU. expressions intracellular ROS,...
The rapid development of methicillin-resistant Staphylococcus aureus (MRSA) drug resistance and the formation biofilms seriously challenge clinical application classic antibiotics. Extracts traditional herb Chenopodium ambrosioides L. were found to have strong antibiofilm activity against MRSA, but their mechanism action remains poorly understood. This study was designed investigate antibacterial activities MRSA flavonoids identified from C. in combination with antibiotics, including...
The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is causing coronavirus disease 2019 (COVID-19) pandemic. Ancient Chinese herbal formulas are effective for diseases caused by viral infection, and their effects on COVID-19 currently being examined. To directly evaluate the role of herbs in inhibiting replication SARS-CoV-2, we investigated how phytochemicals from interact with RNA-dependent RNA polymerase (RdRP). Total 1025 compounds were screened, then 181compounds...