A5038989490- HIV Research and Treatment
- Autophagy in Disease and Therapy
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Health and Medical Education
- Antibiotic Use and Resistance
- Cytomegalovirus and herpesvirus research
- Dental Research and COVID-19
- RNA Interference and Gene Delivery
- Hepatitis B Virus Studies
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
Centre d'Immunologie et des Maladies Infectieuses
2021-2022
Sorbonne Université
2021-2022
Centre National de la Recherche Scientifique
2021-2022
Institut de Biologie Intégrative de la Cellule
2021-2022
Université Paris-Saclay
2021-2022
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2021-2022
CEA Paris-Saclay
2021-2022
Inserm
2021-2022
Article10 October 2022Open Access Source DataTransparent process The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC-II molecules Gabriela Sarango orcid.org/0000-0003-3929-7895 Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France Sorbonne Université, INSERM, Center Immunology and Microbial Infections (CIMI-Paris), Paris, Contribution: Formal analysis, Investigation, Methodology, Writing - review & editing...
Click to increase image sizeClick decrease size Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThis work supported Agence Nationale de la Recherche [AutoVirim (ANR-14-CE14-0022)]; sur le Sida et les Hépatites Virales [ECTZ74132]; Université Paris-Saclay [PhD-salary for GS]; Sidaction [17-1-AEQ-11102-1]
Abstract CD4 + T lymphocytes play a major role in the establishment and maintenance of immunity. They are activated by antigenic peptides derived from extracellular or newly synthesized (endogenous) proteins presented on surface antigen presenting cells (APCs) MHC-II molecules. The pathways leading to endogenous presentation remain poorly characterized. We demonstrate here that autophagy receptor, T6BP, influences both autophagy-dependent -independent HIV- HCMV-derived peptides. By studying...
Antecedentes: Los estudiantes de Odontología están involucrados en la prescripción antibióticos; los cuales, a nivel mundial son recetados exceso. Objetivo: Evaluar conocimientos, actitudes y prácticas antibiótica mediante encuesta octavo noveno semestre Odontología. Metodología: Estudio transversal analítico que registró información un solo momento sin interferir muestra, busca explicar asociación entre conocimientos con sexo semestre, el estudio fue realizado 109 estudiantes, una muestra...