A5072977664- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Opioid Use Disorder Treatment
- Cardiac Arrest and Resuscitation
- Healthcare Policy and Management
- Pharmacological Receptor Mechanisms and Effects
- Acute Myocardial Infarction Research
- Receptor Mechanisms and Signaling
- Forensic Toxicology and Drug Analysis
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Schizophrenia research and treatment
- Neurotransmitter Receptor Influence on Behavior
- Ultrasound in Clinical Applications
- Poisoning and overdose treatments
- Heart Rate Variability and Autonomic Control
- Eicosanoids and Hypertension Pharmacology
- Pharmacological Effects and Assays
- Disaster Response and Management
- Pediatric Pain Management Techniques
- Musculoskeletal pain and rehabilitation
- Primary Care and Health Outcomes
- Influenza Virus Research Studies
- Traffic and Road Safety
- Neuroscience and Neuropharmacology Research
Boston University
2015-2024
Boston Medical Center
2015-2024
Southern California Clinical and Translational Science Institute
2024
California Institute of Technology
2023
Pasadena City College
2023
Harvard University
1994-2022
Associated Medical Services
2022
Children's Hospital of Philadelphia
2022
University of Pennsylvania
2022
Massachusetts General Hospital
2022
Discharging patients with acute myocardial infarction or unstable angina from the emergency department because of missed diagnoses can have dire consequences. We studied incidence of, factors related to, and clinical outcomes failure to hospitalize cardiac ischemia.
To check whether the central hypotensive effect of alpha adrenergic agonists is linked with stimulation alpha-2 receptors, such drugs were administered directly to nucleus reticularis lateralis, which an important site for action clonidine. These experiments carried out by microinjections (0.5 microliter on each side) in normotensive cats anesthetized pentobarbital. alpha-Methylnorepinephrine, a selective agonist (0.1-10 micrograms/kg) had no this region, whereas potent alpha-1 as cirazoline...
Article1 February 1956TYPE-SPECIFIC COLD AUTO-ANTIBODIES AS A CAUSE OF ACQUIRED HEMOLYTIC ANEMIA AND TRANSFUSION REACTIONS: BIOLOGIC TEST WITH BOVINE RED CELLSA. S. WIENER, F.A.C.P., L. J. UNGER, COHEN, FELDMANA. FELDMANAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-2-221 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this report is describe an unusual example...
ContextObservational studies of acute myocardial perfusion imaging in emergency department (ED) patients with chest pain have suggested high sensitivity and negative predictive value for cardiac ischemia, but use this method has not been prospectively tested.ObjectiveTo assess whether incorporating resting into an ED evaluation strategy suspected ischemia no initial electrocardiogram (ECG) changes diagnostic improves clinical decision making triage.Design, Setting, PatientsProspective,...
To describe a large cohort of patients who had chest pain following cocaine use, and to determine the incidence clinical characteristics predictive for myocardial infarction in this group patients.A prospective observational study consecutive with cocaine-associated was conducted six municipal hospital emergency departments (EDs). Demographic variables, drug abuse patterns, medical histories, characteristics, ECG results, laboratory data were recorded. Myocardial primary endpoint.Fourteen...
Few studies targeting obesity in serious mental illness have reported clinically significant risk reduction, and none been replicated community settings or demonstrated sustained outcomes after intervention withdrawal. The authors sought to replicate positive health a previous randomized effectiveness study of the In SHAPE program across urban organizations serving an ethnically diverse population.Persons with body mass index (BMI) >25 receiving services three were recruited randomly...
Our previous in vivo electrochemical studies the normotensive rat have shown that there was a positive correlation between hypotensive effect of low doses clonidine (8-40 nmol/kg i.v.) and inhibition metabolic activity catecholaminergic neurons within nucleus reticularis region brain stem. Higher drug (200 were required to decrease locus ceruleus, which is involved sedative clonidine. To investigate further pharmacological mechanism imidazolines, antagonists injected centrally cisterna magna...
Objective Emergency Departments (EDs) offer an opportunity to improve the care of patients with at-risk and dependent drinking by teaching staff screen, perform brief intervention refer treatment (SBIRT). We describe here implementation at 14 Academic EDs a structured SBIRT curriculum determine if this learning experience improves provider beliefs practices. Methods ED faculty, residents, nurses, physician extenders, social workers, Medical Technicians (EMTs) were surveyed prior...
The Helping Older People Experience Success (HOPES) program was developed to improve psychosocial functioning and reduce long-term medical burden in older people with severe mental illness (SMI) living the community. HOPES includes 1 year of intensive skills training health management, followed by a 1-year maintenance phase.To evaluate effects on social functioning, we conducted randomized controlled trial 183 adults SMI (58% schizophrenia spectrum) age 50 at 3 sites who were assigned or...
POPE, HECTOR J.; AUFDERHEIDE, TOM P.; RUTHAZER, ROBIN; WOOLARD, ROBERT H.; FELDMAN, JAMES A.; BESHANSKY, JONI R.; GRIFFITH, JOHN L.; SELKER, HARRY P. Author Information
ABSTRACT Trichomonas vaginalis infection is estimated to be the most widely prevalent nonviral sexually transmitted in world. Wet-mount microscopy common diagnostic method, although it less sensitive than culture. The OSOM Rapid Test (Genzyme Diagnostics, Cambridge, Mass.) (referred here as OSOM) a new point-of-care assay for T. that uses an immunochromatographic capillary flow (dipstick) and provides results 10 min. purpose of this study was determine test characteristics compared those...
Abdominal 64-MDCT for Suspected Appendicitis: The Use of Oral and IV Contrast Material Versus OnlyStephan W. Anderson1, Jorge A. Soto1, Brian C. Lucey1, Al Ozonoff1 2, Jacqueline D. Jordan1, Jirair Ratevosian1, Andrew S. Ulrich3, Niels K. Rathlev3, Patricia M. Mitchell3, Casey Rebholz3, James Feldman3 T. Rhea1Audio Available | Share
<h3>Importance</h3> Evidence from national studies indicates systematic differences in hospitals which racial/ethnic minorities receive care, with most care obtained a small proportion of hospitals. Little is known about the source these differences. <h3>Objectives</h3> To examine patterns emergency department (ED) destination medical services (EMS) transport according to patient race/ethnicity, and compare between those transported by EMS who did not use EMS. <h3>Design, Setting,...
The increase in opioid overdose deaths has become a national public health crisis. Naloxone is an important tool prevention. Distribution of nasal naloxone been found to be feasible, and effective intervention community settings may have potential high applicability the emergency department, which often initial point care for persons at risk overdose. One safety net hospital introduced innovative policy offer take-home via standing order ensure distribution patients aims this study were...
Rilmenidine has recently been introduced as a new centrally‐acting antihypertensive agent. We examined its cardiovascular effects after intracerebral injection to anaesthetized rabbits. Cumulative doses of rilmenidine injected intracisternally (1 300 μg kg −1 ) led dose‐dependent decreases in arterial blood pressure and heart rate. The effective were lower when centrally than intravenously. Pretreatment with the same dose yohimbine or idazoxan shifted dose‐response curves for hypotensive...
A rapid, low cost, accurate point-of-care (POC) device to detect influenza virus is needed for effective treatment and control of both seasonal pandemic strains. We developed a single-use microfluidic chip that integrates solid phase extraction (SPE) molecular amplification via reverse transcription polymerase chain reaction (RT-PCR) amplify type RNA. demonstrated the ability RNA in human nasopharyngeal aspirate (NPA) swab (NPS) specimens collected at two clinical sites from 2008–2010. The...
Substance use disorders have a profound impact on the course of severe mental illnesses and family, but little research has evaluated family intervention for this population. To address question, randomized controlled trial was conducted comparing brief (2–3 mo) Family Education (ED) program with longer-term (9–18 that combined education teaching communication problem-solving skills, Intervention Dual Disorders (FIDD). A total 108 clients (77% schizophrenia-spectrum) key relative were to...
Historian Philip Burnham traces the complex and still changing relationship between Native Americans national parks from earliest years of National Park Service to latest Congressional initiatives. He recounts how Indians were first removed their traditional lands (which sub