Ayomide Oluwadarasimi Adebesin

ORCID: 0000-0003-3978-9558
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Computational Drug Discovery Methods
  • Evolution and Genetic Dynamics
  • Free Radicals and Antioxidants
  • Wnt/β-catenin signaling in development and cancer
  • Phytochemical and Pharmacological Studies
  • Health Sciences Research and Education
  • Meat and Animal Product Quality
  • Identification and Quantification in Food
  • Psychology of Moral and Emotional Judgment
  • Vaccine Coverage and Hesitancy
  • Inflammatory mediators and NSAID effects
  • Organic Chemistry Cycloaddition Reactions
  • Cardiovascular Disease and Adiposity
  • Medical Research and Practices
  • vaccines and immunoinformatics approaches
  • Click Chemistry and Applications
  • Breast Cancer Treatment Studies
  • Thermal Regulation in Medicine
  • Advanced Breast Cancer Therapies
  • Misinformation and Its Impacts
  • CRISPR and Genetic Engineering
  • Mast cells and histamine
  • Cancer Genomics and Diagnostics
  • Tannin, Tannase and Anticancer Activities

Covenant University
2022-2023

Prostate cancer is the second most common disease in men and sixth leading cause of death from globally, with 20 million expected to be affected by 2024 thus considered as chronic illness which requires immediate attention. As an androgen-dependent that relies on androgen receptor for development progression, inhibition can lead a therapeutic solution, hence serving vital target. This study focused computational analysis inhibitory potentials Vitis vinifera, reported plant anti-cancer...

10.1177/11769351221118556 article EN cc-by-nc Cancer Informatics 2022-01-01

Abstract Background β-catenin is an important unit of the Wnt/β-catenin signaling pathway, a conserved process involving several physiological activities, encompassing differentiation and cell proliferation, etc. The dysfunction or mutation in causing initiation advancement various neoplasm types, including colorectal cancer, breast etc., has been reported. Therefore, therapeutic target. Hence, designing new inhibitors targeted against will prevent cancerous cells’ involvement eliminate...

10.1186/s42269-022-00872-3 article EN cc-by Bulletin of the National Research Centre/Bulletin of the National Research Center 2022-06-27

Despite the rapid developments and advancements to improve treatments, Breast cancer remains one of deadliest health challenges most frequently diagnosed tumor. One major problems with treatment is unique difference that each cancerous cell exhibits. As a result, breast has now become more personalized based on specific features tumor such as overexpression growth factor receptors (Epidermal receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2)), hormone (Human Estrogen alpha...

10.1177/11769351221127862 article EN cc-by-nc Cancer Informatics 2022-01-01

Ready-to-eat meat products offer numerous benefits, but improper handling can pose severe threats to human health. Due its short life span, there is a need for adequate and preservation prevent microbial contamination. Suya, popular ready-to-eat product consumed in Nigeria, be major source of food poisoning if not processed handled properly because it predispose consumers pathogenic microorganisms, heavy metals which result from contaminated water utensils used during processing, polycyclic...

10.18502/jfsh.v9i2.13420 article EN Journal of Food Safety and Hygiene 2023-08-18

Asthma is a chronic and complex pulmonary condition that affects the airways. A total of 250,000 asthma-related deaths are recorded annually several proteins including chymase, spleen tyrosine kinase, prostaglandin D2 receptor have been implicated in pathophysiology asthma. Different anti-inflammatory drugs developed for treatment asthma, particularly corticosteroids, but associated adverse reactions cannot be overlooked. It therefore interest to identify develop small molecule inhibitors...

10.1186/s43141-023-00577-8 article EN cc-by Journal of Genetic Engineering and Biotechnology 2023-11-10

Abstract Objective: Prostate cancer is a prevalent disease among men worldwide, and early detection plays crucial role in improving patient outcomes. It has been suggested that chronic stress could increase the risk of developing prostate cancer, however, association between prostate-specific antigen (PSA) levels stress, as measured by allostatic load (AL) - remains poorly understood. Hence, this study aims to investigate PSA Nigerian men. Methods: A cross-sectional was conducted involving...

10.1158/1538-7755.disp23-b120 article EN Cancer Epidemiology Biomarkers & Prevention 2023-12-01
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