A5052221210- Blood Pressure and Hypertension Studies
- Chronic Kidney Disease and Diabetes
- Cardiovascular Health and Disease Prevention
- Dialysis and Renal Disease Management
- Hormonal Regulation and Hypertension
- Sodium Intake and Health
- Neurobiology and Insect Physiology Research
- Lipoproteins and Cardiovascular Health
- Potassium and Related Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Atrial Fibrillation Management and Outcomes
- Renal function and acid-base balance
- Renal and Vascular Pathologies
- Cardiac pacing and defibrillation studies
- Diet and metabolism studies
- Membrane-based Ion Separation Techniques
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Cardiac Arrhythmias and Treatments
- Electrolyte and hormonal disorders
- Spaceflight effects on biology
- Physiological and biochemical adaptations
- Cephalopods and Marine Biology
- Italian Literature and Culture
- Cancer, Lipids, and Metabolism
Azienda Usl Toscana Centro
2016-2025
Ospedale di Livorno
2007-2024
Società Italiana di Nefrologia
2024
Regione Toscana
2019-2024
Regione Puglia
2019-2024
Italian Society of Physiotherapy
2024
IRCCS Humanitas Research Hospital
2022
Ospedale Monaldi
2021
Azienda Unità Sanitaria Locale di Ferrara
2020
Toscana Biomarkers (Italy)
2019
Microalbuminuria has been shown in approximately 40% of patients with essential hypertension. Previous studies have failed to demonstrate any consistent relationship between microalbuminuria and levels office blood pressure. Because average ambulatory pressure correlates incidence cardiovascular morbidity mortality better than pressure, we studied whether urinary albumin excretion correlate diurnal, nocturnal, or 24-h Sixty-three hypertension 21 healthy volunteers were included the study....
Abstract A significant proportion of patients who suffer from atrial fibrillation and are in need thromboembolic protection not treated with oral anticoagulation or discontinue this treatment shortly after its initiation. This undertreatment has improved sufficiently despite the availability direct anticoagulants which associated less major bleeding than vitamin K antagonists. Multiple reasons account for this, including events ischaemic strokes whilst on anticoagulation, a serious risk...
Background Some patients with essential hypertension manifest greater than normal urinary excretion of albumin (UAE). Authors a few retrospective studies have suggested that there is an association between microalbuminuria and cardiovascular risk. Objective To evaluate whether associated risk renal events. Methods We performed cohort analysis 141 hypertensive individuals followed up for approximately 7 years. Hypertensive were defined as having if the baseline average UAE three urine...
We previously showed that a high salt diet increases glomerular capillary pressure in salt-sensitive hypertensive patients and suggested this may underlie the greater propensity of these to develop renal failure. Because microalbuminuria is considered an initial sign damage, we have tested whether display urinary albumin excretion than salt-resistant patients. Twenty-two were placed on low sodium intake (20 mEq/d) for 7 days followed by (250 more days. Twelve classified as sensitive 10...
To determine the prevalence of increased urinary albumin excretion (UAE) in essential hypertension and to establish whether this abnormality is associated with deranged renal function, we have measured UAE a group 123 patients 110 normal subjects. Mean arterial pressure (MAP) was 96 +/- 0.6 mm Hg subjects 121 0.3 (p less than 0.01). 8.6 0.5 32.9 3.3 mg/24 h Forty percent manifested exceeding 30 had an average 72.0 4.7 h. MAP similar that (121 vs. 0.4 Hg). Creatinine clearance also not...
In response to a high salt intake, salt-sensitive hypertensive individuals retain more sodium and manifest rise in blood pressure greater than that salt-resistant individuals. this study, we tested whether sensitivity might be related at least part reduced secretion of atrial natriuretic peptide (ANP) or abnormal nitric oxide production. We measured plasma ANP NO 2 +NO 3 7 normotensive 13 14 blacks with essential hypertension under conditions low (10 mEq/d) (250 intake. To evaluate possible...
Hyperinsulinemia, insulin resistance, or both have been described in patients with essential hypertension. Previous work from our laboratory has shown that hypertensive microalbuminuria, dyslipidemia and abnormal patterns the diurnal variations of blood pressure are frequently associated. Whether hyperinsulinemia microalbuminuria directly related not determined. To test this possibility, we measured plasma response to an oral glucose load 25 without 20 normotensive control subjects. Serum...
This study aims to estimate the mean annual social cost per patient with chronic kidney disease (CKD) by stages 4 and 5 pre-dialyses components in Italy. The multicenter cross-sectional included all adult outpatients charge of 14 main Nephrology Centers Tuscany Region during 7 weeks from 2012 2013. Direct medical costs have been estimated using tariffs for laboratory tests, diagnostic exams, visits, hospitalization prices drugs. Non-medical expenses low-protein special foods, travel, formal...
Background: The Telemechron project addresses critical needs in telemedicine by evaluating technology assessment frameworks and key performance indicators (KPIs), among other objectives. Effective KPIs are crucial for assessing services, especially terms of their impact on patient outcomes service efficiency. Methods: This study adopted a dual approach to assess the contributions project. Firstly, it applied framework quantitatively evaluate focusing measurable improvements systematic...
Microalbuminuria in patients with essential hypertension is a marker of incipient glomerular dysfunction and clusters lipid hemodynamic abnormalities. Recent evidence has shown that hypertensive microalbuminuria have hyperinsulinemic response to oral glucose, suggesting the presence insulin resistance. To directly test this possibility we studied action two accurately matched groups (n = 10 each) or without (14 +/- 2 versus 52 7 mg/24 h-1, mean three 24-hour collections). In glucose...
Oxidative stress is prevalent in dialysis patients and has been implicated the pathogenesis of cardiovascular disease anemia. Vitamin E a fat-soluble antioxidant that plays central role reducing lipid peroxidation inhibiting generation reactive oxygen species. The aim this cross-over randomized study was to compare effects vitamin E-coated polysulfone (Vit PS) membrane non-vitamin (PS) on inflammatory markers resistance erythropoietin-stimulating agents (ESAs).After 1-month run-in period...
Hypertension and obesity in the young population are major risk factors for renal cardiovascular events, which could arise adulthood. A candidate-gene approach was applied a cohort observational study, we collected data from 2638 high school adolescent students. Participants underwent anthropometric blood pressure (BP) measurements, as well saliva urine sample collection genomic DNA extraction function evaluation, respectively. We tested whether candidate genes previously implicated...
Objectives To review information on cardiovascular health and migration, to stress the attention of researchers that much needs be done in collection sound data Italy allow policy makers identifying this issue as an important public concern. Background In Italy, rate immigrants total number residents increased from 2.5% 1990 7.4% 2010, currently exceeds 10% regions such Lombardia, Emilia Romagna Toscana. Methods A consensus statement was developed by approaching relevant Italian national...