A5053307794- Mycobacterium research and diagnosis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Tuberculosis Research and Epidemiology
- Immune Response and Inflammation
- Immune responses and vaccinations
- Immune cells in cancer
- Pharmacological Effects of Natural Compounds
- Diet and metabolism studies
- Gut microbiota and health
- Cancer, Hypoxia, and Metabolism
- Microbial infections and disease research
- S100 Proteins and Annexins
- Mitochondrial Function and Pathology
- Blood disorders and treatments
Euskadiko Parke Teknologikoa
2020-2024
University of the Basque Country
2021
NEIKER, the Basque Institute for Agricultural Research and Development
2020-2021
Mycobacterium avium subsp. paratuberculosis (Map) is the underlying pathogen causing bovine (PTB), an enteric granulomatous disease that mainly affects ruminants and for which effective treatment needed. Macrophages are primary target cells Map, survives replicates intracellularly by inhibiting phagosome maturation. Neutrophils present at sites during early stages of infection, but seem to be absent in late stage, contrast healthy tissue. Although neutrophil activity has been reported...
Paratuberculosis is a disease of ruminants caused by Mycobacterium avium subsp. paratuberculosis (Map). Vaccination the most cost-effective control method. However, despite fact that macrophages are main target cells for this pathogen, precise mechanisms behind response macrophage to Map infection and how it modified vaccination yet poorly understood. The aim study was investigate effect Silirum
Mycobacterium avium subsp. paratuberculosis (Map) is the etiological agent of (PTB), a chronic intestinal inflammatory disease that causes high economical losses in dairy livestock worldwide. Due to absence widely available preventive or therapeutical treatments, new alternative therapies are needed. In this study, effect probiotic alone combination with commercial vaccine has been evaluated rabbit model. Vaccination enhanced humoral response, exerted training peripheral polymorphonuclear...
Mycobacterium avium subsp. paratuberculosis (Map) causes (PTB), a granulomatous enteritis in ruminants that exerts high economic impact on the dairy industry worldwide. Current vaccines have shown to be cost-effective against Map and some cases confer beneficial non-specific effects other pathogens suggesting existence of trained immunity. Although infection is mainly transmitted by fecal-oral route, oral vaccination has not been deeply studied. Therefore, aim this study was compare route...
Paratuberculosis (PTB) is an enteric granulomatous disease caused by Mycobacterium avium subsp. paratuberculosis (MAP) that mainly affects ruminants. Current vaccines have shown to be cost–effective control reagents, although they are restricted due cross-interference with bovine tuberculosis (bTB). Therefore, novel vaccination strategies needed and this study focused on evaluating alternative routes their effect the local immune response. The MAP oral challenge rabbit model was used...
Abstract Mycobacterium avium subsp. paratuberculosis (Map) is the underlying pathogen causing bovine (PTB), an enteric granulomatous disease that mainly affects ruminants and for which effective treatment needed. Macrophages are primary target cells Map, survives replicates intracellularly by inhibiting phagosome maturation. Neutrophils present at sites during early stages of infection, but seem to be absent in late stage, contrast healthy tissue. Although neutrophil activity has been...