Nisan Hubbard

ORCID: 0000-0003-3995-279X
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About
Contact & Profiles
Research Areas
  • Synthesis and biological activity
  • Metal complexes synthesis and properties
  • Click Chemistry and Applications
  • Health and Medical Research Impacts
  • Career Development and Diversity
  • Diversity and Career in Medicine
  • Autophagy in Disease and Therapy
  • Doctoral Education Challenges and Solutions
  • Histone Deacetylase Inhibitors Research
  • Epigenetics and DNA Methylation
  • Developmental Biology and Gene Regulation
  • Reproductive Biology and Fertility
  • Kruppel-like factors research

West Virginia University
2022-2024

University of North Carolina at Chapel Hill
2022-2024

Northwestern University
2019

Virginia Commonwealth University
2011

Tulane University
2011

Indiana University Bloomington
2011

Indiana University School of Medicine
2011

Pemetrexed (ALIMTA, Lilly) is a folate antimetabolite that has been approved by the U.S. Food and Drug Administration for treatment of non-small cell lung cancer shown to stimulate autophagy. In present study, we sought further understand role autophagy in response pemetrexed test if combination therapy could enhance level toxicity through altered tumor cells. The multikinase inhibitor sorafenib (Nexavar, Bayer), used renal hepatocellular carcinoma, suppresses angiogenesis promotes We found...

10.1158/0008-5472.can-11-0898 article EN Cancer Research 2011-05-28

This study examines the intersectional role of citizenship and gender with career self-efficacy amongst 10,803 doctoral postdoctoral trainees in US universities. These biomedical completed surveys administered by 17 institutions that participated National Institutes Health Broadening Experiences Scientific Training (NIH BEST) Programs. Findings indicate non-citizen is significantly lower than citizen trainees. While efficacy was observed women compared men, it even for female Results suggest...

10.1371/journal.pone.0296246 article EN cc-by PLoS ONE 2024-03-20

Abstract The Notch pathway plays diverse and complex roles in cell signaling during development. In the mammalian ovary, is important for initial formation growth of follicles, regulating proliferation differentiation follicular granulosa cells periovulatory period. This study seeks to determine contribution female germ toward activation subsequent maintenance within somatic ovary. To address this issue, transgenic reporter (TNR) mice were crossed with Sohlh1-mCherry (S1CF) visualize...

10.1210/en.2019-00564 article EN Endocrinology 2019-10-14

Abstract This study examines the intersectional role of citizenship and gender with career self-efficacy amongst 10,803 doctoral postdoctoral trainees in US universities. These biomedical completed surveys administered by 17 institutions that participated National Institutes Health Broadening Experiences Scientific Training (NIH BEST) Programs. Findings indicate non-citizen is significantly lower than citizen trainees. While efficacy was observed women compared men, it even for female...

10.1101/2023.02.19.526477 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2023-02-21

<div>Abstract<p>Pemetrexed (ALIMTA, Lilly) is a folate antimetabolite that has been approved by the U.S. Food and Drug Administration for treatment of non–small cell lung cancer shown to stimulate autophagy. In present study, we sought further understand role autophagy in response pemetrexed test if combination therapy could enhance level toxicity through altered tumor cells. The multikinase inhibitor sorafenib (Nexavar, Bayer), used renal hepatocellular carcinoma, suppresses...

10.1158/0008-5472.c.6502511 preprint EN 2023-03-30

<div>Abstract<p>Pemetrexed (ALIMTA, Lilly) is a folate antimetabolite that has been approved by the U.S. Food and Drug Administration for treatment of non–small cell lung cancer shown to stimulate autophagy. In present study, we sought further understand role autophagy in response pemetrexed test if combination therapy could enhance level toxicity through altered tumor cells. The multikinase inhibitor sorafenib (Nexavar, Bayer), used renal hepatocellular carcinoma, suppresses...

10.1158/0008-5472.c.6502511.v1 preprint EN 2023-03-30

Abstract The present study examines racial, ethnic, and gender disparities in career self-efficacy amongst 6077 US citizens naturalized graduate postdoctoral trainees. Respondents from biomedical fields completed surveys administered by the National Institutes of Health Broadening Experiences Scientific Training (NIH BEST) programs across 17 institutional sites. Graduate demographic survey response data were examined to evaluate impact intersectional identities on trainee self-efficacy....

10.1101/2022.10.21.512368 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-10-21
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