Manuel Zagarrigo

ORCID: 0000-0003-4008-1477
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About
Contact & Profiles
Research Areas
  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • Antibiotics Pharmacokinetics and Efficacy
  • COVID-19 Clinical Research Studies
  • Antimicrobial Resistance in Staphylococcus
  • Orthopedic Infections and Treatments

Azienda USL di Bologna
2025

University of Bologna
2023

Background: Daptomycin plus fosfomycin combination therapy is a valuable strategy for treating staphylococcal osteoarticular infections (OIs), but hypernatremia and hypokalemia due to sodium overload are important issues. The aim of this study was assess the likelihood attaining pharmacokinetic/pharmacodynamic (PK/PD) target AUC/MIC > 66.6 and/or 70%t MIC with continuous infusion (CI) at recommended vs. reduced dose in patients OIs receiving high-dose daptomycin. Adverse events were also...

10.3390/antibiotics14020139 article EN cc-by Antibiotics 2025-02-01

Literature offers plenty of cases immunocompromised patients, who develop chronic and severe SARS-CoV-2 infections. The aim this study is to provide further insight into evolutionary dynamic taking exam a subject suffering from follicular lymphoma, developed persistent infection for over 7 months. Eight nasopharyngeal swabs were obtained, analyses by qRT-PCR diagnostic purposes. All them considered eligible (Ct < 30) NGS sequencing. Sequence analysis showed that all sequences matched the...

10.3390/v15020291 article EN cc-by Viruses 2023-01-19
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