- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 Clinical Research Studies
- Antimicrobial Resistance in Staphylococcus
- Orthopedic Infections and Treatments
Azienda USL di Bologna
2025
University of Bologna
2023
Background: Daptomycin plus fosfomycin combination therapy is a valuable strategy for treating staphylococcal osteoarticular infections (OIs), but hypernatremia and hypokalemia due to sodium overload are important issues. The aim of this study was assess the likelihood attaining pharmacokinetic/pharmacodynamic (PK/PD) target AUC/MIC > 66.6 and/or 70%t MIC with continuous infusion (CI) at recommended vs. reduced dose in patients OIs receiving high-dose daptomycin. Adverse events were also...
Literature offers plenty of cases immunocompromised patients, who develop chronic and severe SARS-CoV-2 infections. The aim this study is to provide further insight into evolutionary dynamic taking exam a subject suffering from follicular lymphoma, developed persistent infection for over 7 months. Eight nasopharyngeal swabs were obtained, analyses by qRT-PCR diagnostic purposes. All them considered eligible (Ct < 30) NGS sequencing. Sequence analysis showed that all sequences matched the...