A5102888009- Educator Training and Historical Pedagogy
- Australian History and Society
- Evaluation of Teaching Practices
- Higher Education Learning Practices
- Cytokine Signaling Pathways and Interactions
- Genetic factors in colorectal cancer
- COVID-19 and healthcare impacts
- Herpesvirus Infections and Treatments
- Asthma and respiratory diseases
- Colorectal Cancer Treatments and Studies
- Innovative Teaching Methodologies in Social Sciences
- Memory, Trauma, and Commemoration
- Cancer-related molecular mechanisms research
- Helicobacter pylori-related gastroenterology studies
- Cultural Heritage Management and Preservation
- Museums and Cultural Heritage
- Cancer Immunotherapy and Biomarkers
- Studies on Chitinases and Chitosanases
- Health Systems, Economic Evaluations, Quality of Life
- IL-33, ST2, and ILC Pathways
- Allergic Rhinitis and Sensitization
- Canadian Identity and History
- Commonwealth, Australian Politics and Federalism
- Higher Education Practises and Engagement
- Cardiac, Anesthesia and Surgical Outcomes
The University of Adelaide
2016-2024
Charlottesville Medical Research
2024
University of Arizona
2024
John Wiley & Sons (United States)
2023
Catholic Charities
2023
Charité - Universitätsmedizin Berlin
2022
VA Portland Health Care System
2022
Primary Health Care
2022
WinnMed
2021
NIHR Birmingham Biomedical Research Centre
2021
This author discusses the relationship between use of presentation software and maintenance student interest in university lectures. The evidence surveyed students suggests that PowerPoint, used as a tool lectures, is pedagogically effective only while it provides variety stimulates learning environment. That stimulation can be increased if Power Point to bridge direct constructivist teaching models.
Maladaptive, Th2-polarized inflammatory responses are integral to the pathogenesis of allergic asthma. As regulators T cell activation, dendritic cells (DCs) important mediators asthma, yet precise signals which render endogenous DCs "pro-asthmatic", and extent these regulated by pulmonary environment host genetics, remains unclear. Comparative phenotypic functional analysis DC populations in mice susceptible (A/J), or resistant (C3H) experimental revealed that susceptibility airway...
Abstract The complement fragment C5a plays dual roles in the development of experimental allergic asthma. It protects from pulmonary allergy by a regulatory effect on dendritic cells during allergen sensitization, but is proallergic effector phase. can bind to two distinct receptors (i.e., receptor and receptor-like 2 [C5L2]). functional role C5L2 vivo remains enigmatic. In this study, we show models OVA- house dust mite (HDM)-induced asthma that C5L2-deficient mice are protected airway...
SUMMARY A mutant of herpes simplex virus type 1 [HSV- 1(HFEM)], tsB7, appears to have two temperature-sensitive functions. One is required during the first hour infecting a cell (suggesting that it performed by virion protein) and other non-essential function 'early shut-off' cellular protein synthesis, which mediated protein. The latter remained in revertant (RC2) grown at non-permissive temperature (39 °C). However, under these conditions RC2 did cause inhibition host showing 'delayed...
Expression of microRNAs (miRs) has been shown to be altered in many solid tumours and is being explored melanoma. The malignant potential some melanocytic lesions difficult predict. We hypothesised that characterisation miR expression borderline proliferations would lead the identification a molecular profile could used with known prognostic factors differentiate high potential. (benign naevi, melanoma tumours) was evaluated by real-time PCR. PCR analysis revealed primary cutaneous melanomas...
The role of complement in the development maladaptive immunity experimental allergic asthma is unclear. In this study, we show that C3a receptor (C3aR)-deficient mice are protected from Th2 a model house dust mite-induced asthma. C5a (C5aR)-targeting C3aR-deficient during allergen sensitization not only reversed protective effect but enhanced cytokine production, airway inflammation, and responsiveness, suggesting reduced phenotype results C5aR signaling. support view, expression pulmonary...
Despite current polysaccharide and conjugate vaccine use, pneumococcal diseases remain prevalent in older adults. VAX-24 is a 24-valent (PCV) containing eCRM, proprietary carrier protein with non-native amino acids (para-azidomethyl-L-phenylalanine) that undergo site-specific conjugation to polysaccharides have been activated small-molecule linker (dibenzocyclooctyne). Site-specific utilizing click chemistry enables consistent exposure of T-cell epitopes, reduction ratio, enhances...
Those who make memorials for the victims of motor vehicle crashes assume an authority to do so that stems from three main elements experience: overwhelming empowerment grief; belief presence deceased can be felt and recognized; understanding place where life was lost is a special memorialization. The strength grief, power importance allows ordinary people and, therefore, challenge church government as official purveyors regulators mourning ritual.
Exposure to airborne particulate matter (PM), a major component of air pollution, has been associated with increases in both exacerbations and hospitalizations for asthma. We have previously shown that exposure ambient PM collected urban Baltimore (AUB) induces airway hyperresponsiveness (AHR), eosinophilic neutrophilic inflammation, the recruitment T cells. However, mechanism(s) by which it these features asthma remains unknown.We investigated whether lymphocytes play role AUB-induced...
Abstract Introduction CONTACT is a national multidisciplinary study assessing the impact of COVID-19 pandemic upon diagnostic and treatment pathways among patients with pancreatic ductal adenocarcinoma (PDAC). Methods The consecutive newly diagnosed PDAC from pre-COVID-19 cohort (07/01/2019-03/03/2019) were compared to during first wave UK (‘ COVID’ cohort, 16/03/2020-10/05/2020) , 12-month follow-up. Results Among 984 (pre-COVID: n = 483, COVID: 501), COVID was less likely receive staging...
Providing care over telehealth grew slowly until the COVID-19 pandemic. Since onset of pandemic, providing mental health was readily adapted to virtual means; however, clinical trial research is nascent in adapting methods and procedures world.
The comparative study of roadside memorials in New South Wales, Australia, and Texas, United States, raises questions about the consistency memorial form practice between societies with diverse ethnic religious profiles different historical backgrounds. This article compares two societies, suggests that sub-group affiliation accounts for local individual differences what is essentially an international phenomenon powered by developments motoring culture, postmodernism, globalization....
Higher education in Australia is currently a state of flux, with the Federal Government’s Tertiary Education Quality and Standards Agency commencing operations January 2012. The ‘After Project’ has been working Australian university history departments Historical Association, educating empowering discipline to act as united community assert ownership standards process. This article provides stocktake achievements challenges After Project faced coming terms new environment resultant demands...
Funding pressure on the pharmaceutical industry to deliver new medicines market under aggressive timelines has led a demand for analytical tools with higher detection sensitivity, increased throughput, and automation speed up research discovery efforts converge upon clinically fit leads faster. In quest therapeutic antibodies, early adoption of interaction analysis platforms utilizing surface plasmon resonance (SPR) provides insightful molecular-level information about binding properties...
AbstractAbstractIn the current culture of regulation in higher education and, turn, history discipline, it is timely to problematize discipline standards relation student agency and creativity. This article argues that through inclusion a critical orientation engaged pedagogy, historians have opportunity bring more agentic dimension disciplinary conversation. Discipline privilege arrogant historical moment sector when certain skills development knowledge creation becomes hegemonic discourse....
Literature pertaining to the scholarship of teaching and learning (SoTL) is growing but there are few studies dealing with disciplinary differences. The SoTL relating History a recently emerging development. But what use for if it can not be translated into improving practice? This paper examines process identifying current thinking in specific History, especially historical thinking, applying development new history curriculum first year students.
Background: Development of more effective therapies for genital herpes simplex virus type-2 (HSV-2) infections remains a priority. The toll-like receptors (TLR) are attractive targets the immunomodulation primary and recurrent infection. guinea pig model HSV-2 disease was therefore used to evaluate efficacy new TLR-7 agonist, SMIP-7.7. Methods: effects SMIP-7.7 at concentrations between 0.90% 0.09% were compared vehicle control or Aldara® (3M Health Care Limited, Northridge, CA, USA) as...