Xuan Cai

ORCID: 0000-0003-4012-2726
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About
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Research Areas
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Retinal and Macular Surgery
  • Optical Coherence Tomography Applications
  • Retinal Development and Disorders
  • Ophthalmology and Visual Impairment Studies
  • Intraocular Surgery and Lenses
  • Stability and Control of Uncertain Systems
  • Material Properties and Applications
  • Retinopathy of Prematurity Studies
  • Aeroelasticity and Vibration Control
  • Ophthalmology and Visual Health Research
  • Ocular Diseases and Behçet’s Syndrome
  • Corneal surgery and disorders
  • Computer Graphics and Visualization Techniques
  • Lysosomal Storage Disorders Research
  • Advanced Nanomaterials in Catalysis
  • Agricultural pest management studies
  • Eicosanoids and Hypertension Pharmacology
  • Advanced Vision and Imaging
  • Autophagy in Disease and Therapy
  • Microstructure and mechanical properties
  • Smart Materials for Construction
  • interferon and immune responses

Shanghai Sixth People's Hospital
2018-2023

Shanghai Jiao Tong University
2003-2022

XinHua Hospital
2014-2016

Institute of Acoustics
1996

<h3>Aims</h3> To describe the prevalence and associations of epiretinal membrane (ERM) in an elderly urban Chinese population China. <h3>Methods</h3> A population-based cross-sectional study was conducted using a cluster random sample residents aged 50 years or older living Jiangning Road Sub-district, Shanghai, All participants underwent standardised interview comprehensive eye examinations, including digital retinal photography spectral domain optical coherence tomography (SD-OCT)...

10.1136/bjophthalmol-2015-307050 article EN British Journal of Ophthalmology 2015-06-11

Methods.: A population-based, cross-sectional study was conducted using a cluster random sample of residents aged 50 years or older living in the Jiangning Road Subdistrict, Jing'an District, Shanghai, China. All participants underwent standardized interview and comprehensive eye examinations, including digital retinal photography spectral-domain optical coherence tomography (OCT) examinations both eyes between November 2012 February 2013. Trained graders assessed presence severity AMD...

10.1167/iovs.14-14899 article EN Investigative Ophthalmology & Visual Science 2014-09-05

Retinal neurodegeneration develops early in the course of diabetic retinopathy (DR), and our previous research showed that succinate accumulation results retinal ganglion cells (RGCs) dysfunction retinas rats with DR. Succinate can enhance lysine succinylation, but succinylation DR is not well understood. In this study, we investigated role succinylome identified key factor process. TMT labeling LC-MS/MS analysis were combined to quantify differentially succinylated proteins between vitreous...

10.1038/s41420-022-00861-5 article EN cc-by Cell Death Discovery 2022-02-14

Abstract Objective . Visual outcomes provided by present retinal prostheses that primarily target ganglion cells (RGCs) through epiretinal stimulation remain rudimentary, partly due to the limited knowledge of responses under electrical stimulation. Better understanding how different regions can be quantitatively controlled with high spatial accuracy, will beneficial design micro-electrode arrays and strategies for next-generation wide-view, high-resolution implants. Approach A computational...

10.1088/1741-2552/ac5b18 article EN Journal of Neural Engineering 2022-03-07

To evaluate the effectiveness of endolaser photocoagulation by a two-port pars plana nonvitrectomy approach for treating Coats' disease with shallow exudative retinal detachment.This study included 24 patients (23 boys an age range 2-17 years, and one girl, 6 years) stage 3 (25 eyes) from December 2012 May 2014 at single center. All 25 eyes were complicated serous or total detachment received none-vitrectomized endolaser: two (23- 25-gauge) incisions routinely made mm posterior to corneal...

10.1007/s00417-015-2984-4 article EN cc-by Graefe s Archive for Clinical and Experimental Ophthalmology 2015-03-20

To describe the natural course of myopic traction maculopathy (MTM) and determine predictive factors for its progression visual prognosis.This retrospective observational study included 113 MTM patients (113 eyes). Best-corrected acuity (BCVA) measurements optical coherence tomography findings were recorded.Over a mean follow-up 38.2 ± 11.1 months, 49 eyes (43.4 %) progressed. The rate outer schisis prominently located in fovea or posterior staphyloma was significantly higher than that...

10.1186/s12886-021-02087-y article EN cc-by BMC Ophthalmology 2021-09-25

To perform a quantitative analysis of retinal microvasculature in patients with early-stage diabetic retinopathy (DR) using wide-field swept-source optical coherence tomography angiography (SS-OCTA). METHODS: One hundred nineteen eyes 119 patents (67 no DR and 52 mild-moderate nonproliferative (NPDR)) were enrolled this observational cross-sectional cohort study, an age-matched group consisting 39 non-diabetic subjects set as the control. Each participant underwent full ophthalmic...

10.1186/s12886-022-02724-0 article EN cc-by BMC Ophthalmology 2022-12-06

Nickel titanium (NiTi) lattice structures prepared by laser powder bed fusion (LPBF) have great application potential, due to their unique shape memory effect, superelasticity, and controlled geometry characteristics. In this study, the NiTi I-graph-wrapped package (I-WP) body-centered cubic (BCC) structure samples were LPBF process. The uniaxial compression properties cyclic of process studied. results showed that surfaces very rough adhered with many particles. sample optimization design...

10.36922/msam.3380 article EN cc-by Materials Science in Additive Manufacturing 2024-06-20

Inverse optimal control for nonlinear systems with structural uncertainty is considered. Based on the Lyapunov function, a theorem globally asymptotic stability presented. From this less conservative condition inverse derived. The result used to design an controller class of systems, that improves and extends existing results. considered also enlarged. simulation results show effectiveness method.

10.1049/ip-cta:20041163 article EN IEE Proceedings - Control Theory and Applications 2005-01-01

10.1016/0003-682x(95)00061-d article EN Applied Acoustics 1996-05-01

Background Myopia subjects usually have long axial lengths and are predisposed to deep anterior chamber depths open angles. Jiangning eye study is a randomized, population based in Shanghai determine whether myopia has an effect on the prevalence of occludable Methods A total 2478 residents aged 50 years over were randomly selected, 2044 (82.5%) individuals them participated ophthalmic examinations between November 2012 February 2013. Eye included autorefraction, noncontact tonometry,...

10.1371/journal.pone.0165281 article EN cc-by PLoS ONE 2016-10-20

Objectives To investigate the prevalence and risk factors of uncorrected refractive error (URE) in an elderly urban Chinese population China. Design A population-based cross-sectional study. Methods The study was conducted using a cluster random sample residents aged 50 years or older living Jiangning Road subdistrict, Shanghai, All participants underwent standardised interview eye examinations, including presenting visual acuity (PVA) best-corrected (BCVA) between November 2012 February...

10.1136/bmjopen-2017-021325 article EN cc-by BMJ Open 2018-03-01

Abstract Background To assess and characterize neovascularization of the optic disc (NVD) using optical coherence tomography angiography (OCTA) different OCTA-based methods. Methods This retrospective, observational study included patients who were suspected having early PDR with no presence clinically apparent (NV) bur diagnosed proliferative diabetic retinopathy (PDR), or severe NPDR. Patients underwent standard clinical examinations OCTA imaging a 6 × montage scan. Two trained graders...

10.1186/s12886-022-02351-9 article EN cc-by BMC Ophthalmology 2022-03-16

Optical coherence tomography has become an indispensable diagnostic tool in ophthalmology for imaging the retina and anterior segment of eye. However, depth optical is limited by light attenuation tissues due to scattering absorption. In this study rabbit eye both ex vivo vivo, posterior segments was extended using clearing agents reduce multiple scattering. The sclera, iris, ciliary body were clearly visualized direct application glycerol at incision on conjunctiva, boundary sclera even...

10.1177/1535370220949834 article EN Experimental Biology and Medicine 2020-08-13

To evaluate the role of CCAAT/enhancer-binding protein β (C/EBP (C/EBP. Rats with OIR were exposed to alternating hypoxic and hyperopic conditions for 14 days. Then, rats assigned randomly groups that received intravitreal injections either shRNA lentiviral particles targeting C/EBP In rats, expression levels P < 0.01). The p-C/EBP p-C/EBP. inhibits RNV in OIR. A potential mechanism may be activity increases its overexpression, which turn aggravates amount retinal vascular damage promotes...

10.1155/2020/2789209 article EN cc-by Journal of Diabetes Research 2020-03-09

To evaluate the prevalence and types of artifacts in ultrawide-field swept-source optical coherence tomography angiography (SS-OCTA) scans diabetic retinopathy (DR) patients.

10.1080/02713683.2023.2296362 article EN Current Eye Research 2023-12-20

Abstract Background: To describe the natural course of myopic traction maculopathy (MTM) and determine predictive factors for its progression visual prognosis. Methods: This retrospective observational study included 113 MTM patients (147 eyes). Best-corrected acuity (BCVA) measurements optical coherence tomography findings were recorded. Results: Over a mean follow-up 38.2 ± 11.1 months, 58 147 eyes (39.5%) progressed. The rate outer schisis prominently located in fovea or posterior...

10.21203/rs.3.rs-211164/v1 preprint EN cc-by Research Square (Research Square) 2021-02-10
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