Jianxiong Xu

ORCID: 0000-0003-2026-3791
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Research Areas
  • Animal Nutrition and Physiology
  • Viral gastroenteritis research and epidemiology
  • Influenza Virus Research Studies
  • Adipose Tissue and Metabolism
  • Viral Infections and Immunology Research
  • Respiratory viral infections research
  • Virology and Viral Diseases
  • Vaccine Coverage and Hesitancy
  • Fatty Acid Research and Health
  • Ginger and Zingiberaceae research
  • Birth, Development, and Health
  • SARS-CoV-2 and COVID-19 Research
  • Reproductive System and Pregnancy
  • Aquaculture Nutrition and Growth
  • Animal Disease Management and Epidemiology
  • Hepatitis B Virus Studies
  • Genomics, phytochemicals, and oxidative stress
  • Phytoestrogen effects and research
  • Pharmacological Effects of Natural Compounds
  • Coenzyme Q10 studies and effects
  • Diet and metabolism studies
  • Peroxisome Proliferator-Activated Receptors
  • Biochemical Acid Research Studies
  • Inflammasome and immune disorders
  • Immune responses and vaccinations

Shanghai Jiao Tong University
2013-2025

University of Saint Joseph
2024-2025

Putian University
2024-2025

Chongqing University
2020-2024

Guangzhou Center for Disease Control and Prevention
2010-2024

Guangzhou Medical University
2024

Xihua University
2024

Hunan University of Technology
2016-2023

Southern Medical University
2023

Nanfang Hospital
2023

The objective of this experiment was to investigate the influence weaning stress and an antioxidant blend on gut health free radical metabolism in postweaning pigs. A total 96 pigs from 12 litters were randomly divided by litter 3 groups with 4 each. control group fed basal diet, diet supplemented blend. suckling normally during experimental period other 2 treatments weaned at 21 d age. Morphology different parts intestines used as a measure intestinal barrier function. Activities superoxide...

10.2527/jas.2011-4444 article EN Journal of Animal Science 2012-02-04

The objective of this experiment was to investigate the influence weaning stress and an antioxidant blend on gut health free radical metabolism in postweaning pigs. A total 96 pigs from 12 litters were randomly divided by litter 3 groups with 4 each. control group fed basal diet, diet supplemented blend. suckling normally during experimental period other 2 treatments weaned at 21 d age. Morphology different parts intestines used as a measure intestinal barrier function. Activities superoxide...

10.2527/jas.2012-4444 article EN Journal of Animal Science 2012-08-01

Significant embryo loss remains a serious problem in pig production. Reactive oxygen species (ROS) play critical role embryonic implantation and placentation. However, the potential mechanism of ROS on porcine trophectoderm (pTr) cell fate during peri-implantation period has not been investigated. This study aimed to elucidate effects pTr phenotypes regulatory attachment differentiation. Herein, results showed that exogenous H 2 O inhibited viability, arrested cycle at S G2/M phases,...

10.1152/ajpcell.00256.2018 article EN AJP Cell Physiology 2018-11-28

This study investigated the effects of weaning on hepatic redox status, apoptosis, function, and mitogen-activated protein kinase (MAPK) signaling pathways during first week after in piglets. A total 12 litters piglets were weaned at d 21 divided into group (WG) control (CG). Six from each slaughtered 0 (d 20, referred to weaning), 1, 4, 7 weaning. Results showed that significantly increased concentrations free radicals H2O2 NO, malondialdehyde (MDA), 8-hydroxy-2'-deoxyguanosine (8-OHdG),...

10.1155/2016/4768541 article EN cc-by Oxidative Medicine and Cellular Longevity 2016-01-01

A patient may have been infected with highly pathogenic avian influenza virus H5N1 in Guangzhou, People's Republic of China, at a food market that had live birds.Virus genes were detected 1 79 wire cages for birds 9 markets.One 110 persons the poultry business markets neutralizing antibody against H5N1.H ighly (HPAI) 202 worldwide and killed 113 as April 30, 2006 (1).Most patients exposed to ill or dead involved slaughter preparation human (2).However, 19 confirmed cases 5 no history direct...

10.3201/eid1211.060675 article EN Emerging infectious diseases 2006-11-01

In this study, antioxidant capability and protective effect of probiotics on reproductive damage induced by diet oxidative stress were investigated. Thirty male Sprague-Dawley rats randomly divided into three groups with 10 in each group. The control group consumed a normal standard (5% fat, w/w). other two treatment fed high-fat (20% w/w), supplemented 2% (w/w), respectively. At the end experimental period, that is, after 6 weeks, killed. Activities superoxide dismutase (SOD), glutathione...

10.1017/s1751731112001528 article EN cc-by-nc-nd animal 2012-07-24

Abstract The development of nanomedicines provides new opportunities for the treatment atherosclerosis (AS) due to their great advantages such as improved drug solubility, enhanced bioavailability and reduced side effects. Despite these advantages, are still facing some challenges. problems remain in short circulation life, lack specific targeting poor release controllability. In order overcome shortages conventional nanomedicines, combination biomimetic strategy with smart nanoagents has...

10.1093/rb/rbab033 article EN cc-by Regenerative Biomaterials 2021-06-21

Abstract For wider‐band and stronger electromagnetic (EM) wave absorption, macroporous short carbon fibers/mullite matrix (C f /Mu) composites were prepared via introducing fibers (0, 0.7, 1.3 vol%) with length of 2‐3 mm into mullite ceramic by gel‐casting. The density as‐prepared C /Mu decreases from 2.93 g/cm 3 to 2.74 , while the porosity increases 3.32% 10.76% rise in content. diameter macropores is ranging several microns tens microns. Complex permittivity dielectric loss X‐band...

10.1111/jace.17401 article EN Journal of the American Ceramic Society 2020-08-07

N -acetyl cysteine (NAC) has been widely used for preventing reactive oxygen species-induced damage. However, little is known as to whether dietary NAC supplementation would alleviate intestinal injury in weaned piglets. The present study evaluated the effect of on enterocyte apoptosis and intracellular signalling pathways' response weaning stress. control piglets were normally suckling, groups fed basal diet basal+NAC from 14 25 d age, respectively. Compared with piglets, increased cortisol...

10.1017/s0007114513001608 article EN British Journal Of Nutrition 2013-06-03

Guangdong province attracted more than 31 million migrants in 2010. But few studies were performed to estimate the complete and age-appropriate immunization coverage determine risk factors of migrant children. 1610 children aged 12–59 months from 70 villages interviewed Guangdong. Demographic characteristics, primary caregiver's knowledge attitude toward immunization, child's history obtained. UTD rates for following five vaccines overall series (1:3:3:3:1 series) assessed: one dose BCG,...

10.1186/1471-2458-14-203 article EN cc-by BMC Public Health 2014-02-26

Pterostilbene is more effective than resveratrol in alleviating liver injury, facilitating redox status, and improving mitochondrial function of piglets.

10.1039/d0fo00732c article EN Food & Function 2020-01-01

Oxidative stress can induce inflammation and tight junction disruption in enterocytes. The initiation of is thought to commence with the activation ROS/NLRP3/IL-1β signaling pathway, marking a crucial starting point process. In our previous studies, we found that microbe-derived antioxidants (MAs) showed significant potential enhancing both antioxidant capabilities anti-inflammatory effects. main aim this research was investigate ability MAs protect cells from oxidative caused by H2O2,...

10.3390/antiox13050533 article EN cc-by Antioxidants 2024-04-27

The attenuated live varicella vaccine had been shown to be effective in preventing and reducing the disease burden United States. However, little work has done on investigating effectiveness China where 3 vaccines are available. Although contain same strain of virus, licensed were from manufacturers different one We conducted a matched case-control study assess use China.In 2005, we enrolled 1000 cases Guangzhou, controls by age place residence. children clinically diagnosed with acute onset...

10.1097/inf.0b013e3181d7380e article EN The Pediatric Infectious Disease Journal 2010-03-18

Abstract The aim of this study was to compare the free radical scavenging ability and intestinal epithelial cell protective effects Java tea ( Orthosiphon stamineus ) root extracts (ORE), stem (OSE), leaf (OLE) determine potential by‐products. were prepared using a standard water–ethanol method. antioxidant activity tested by H 2 O ‐induced model high‐fat diet‐induced mice model, respectively. results showed that total phenolic acid flavonoid content relative different in ORE, OSE, OLE. ORE...

10.1002/fsn3.584 article EN cc-by Food Science & Nutrition 2018-02-06

Objective: Hand, foot, and mouth disease (HFMD) is an important public health issue in China. Although efficacy has been demonstrated by randomized controlled trials, the evidence for effectiveness of monovalent Enterovirus 71 (EV71) vaccine against HFMD remains unknown. This study aimed to assess Guangzhou, China.Methods: Routinely collected vaccination surveillance data were captured from China Information System Disease Control Prevention. We estimated EV71 using spatial ecologic...

10.1080/21645515.2020.1763076 article EN Human Vaccines & Immunotherapeutics 2020-06-12
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