A5064372548- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Respiratory Support and Mechanisms
- Peripheral Artery Disease Management
- Mechanical Circulatory Support Devices
- Intracranial Aneurysms: Treatment and Complications
- Inhalation and Respiratory Drug Delivery
- Organ Transplantation Techniques and Outcomes
- Vascular Procedures and Complications
- Coronary Interventions and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Phonocardiography and Auscultation Techniques
- Restraint-Related Deaths
- Tissue Engineering and Regenerative Medicine
- Cardiac Arrest and Resuscitation
- Neonatal Respiratory Health Research
- Transplantation: Methods and Outcomes
Columbia University
2022-2024
Columbia University Irving Medical Center
2022-2024
Texas Health Dallas
2022
Abstract Pulmonary air leak is the most common complication of lung surgery, contributing to post‐operative morbidity in up 60% patients; yet, there no reliable treatment. Available surgical sealants do not match demanding deformation mechanics tissue; and therefore, fail seal leak. To address this therapeutic gap, a sealant with structural mechanical similarity subpleural designed, developed, systematically evaluated. This “lung‐mimetic” hydrofoam material that has alveolar‐like porous...
The airway epithelium lining the luminal surface of respiratory tract creates a protective barrier that ensures maintenance tissue homeostasis and prevention diseases. epithelium, unfortunately, is frequently injured by inhaled toxic materials, trauma, or medical procedures. Substantial repeated epithelial injury can lead to dysregulated intrinsic repair pathways aberrant remodeling dysfunctional epithelium. While disruption in integrity directly linked degraded function, correlation between...
ABSTRACT Despite over 30 years of intensive research for targeted therapies, treatment acute respiratory distress syndrome (ARDS) remains supportive in nature. With mortality upwards 30%, a high-fidelity pre-clinical model ARDS, on which to test novel therapeutics, is urgently needed. We used the Yorkshire breed swine induce reproducible ARDS human-sized allow study new from both mechanistic and clinical standpoints. For this, animals were anesthetized, intubated mechanically ventilated,...