- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Dermatoglyphics and Human Traits
- Respiratory and Cough-Related Research
- Sports Performance and Training
- Sleep and Wakefulness Research
- Sleep and related disorders
- Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Medication Adherence and Compliance
- Infectious Diseases and Tuberculosis
- Drug-Induced Adverse Reactions
- Mycobacterium research and diagnosis
- Historical Turkish Studies
- Epilepsy research and treatment
- Venous Thromboembolism Diagnosis and Management
- Neuroendocrine Tumor Research Advances
- Bacterial Infections and Vaccines
- Lung Cancer Research Studies
- Tuberculosis Research and Epidemiology
- Peptidase Inhibition and Analysis
Sağlık Bilimleri Üniversitesi
2020-2024
University of Health Science
2022-2024
Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi
2013-2022
University of Health Sciences
2022
Turkish Thoracic Society
2022
Sleep Research Society
2022
Universidad CES
2021
Ankara Spine Center
2010-2020
Chest Diseases Hospital
2018
Hacettepe University
2015-2017
The aim of this case control study is to assess the relationship between serum C-reactive protein (CRP) levels and well-known clinical parameters in Chronic obstructive pulmonary disease (COPD) considering impact smoking behavior, biomass exposure accompanying entities, namely hypertension, systemic hypertension diabetes mellitus.
The T-SPOT.TB test does not cross-react with Bacille Calmette-Guérin or most non-tuberculosis mycobacterium species, and is based on IFN-gamma responses to Mycobacterium tuberculosis-specific antigens. objective of this study was compare tuberculin skin (TST) results used in the diagnosis active tuberculosis (TB) as well latent infection (LTBI). A total 136 subjects participated three different groups (47 patients pulmonary TB, 47 healthy persons without M. exposure, 42 hospital members a...
Orexin-A is a neuropeptide involved in the regulation of food intake and sleep-wake cycle. This study investigated plasma orexin-A levels sleep clinic cohort, adjusting for smoking habits, 76 participants comprising 41 with obstructive apnoea (OSA) (apnoea-hypopnoea index [AHI] 44.1 +/- 19.1 events/h) 35 without OSA (AHI 6.3 4.7 events/h). Plasma were significantly lower patients (15.0 4.6 ng/ml) compared those (31.4 6.5 ng/ml). In non-OSA subjects, there was no significant difference...
In this study, we aimed to evaluate the accuracy of original and simplified pulmonary embolism (PE) severity index (PESI) predict all-cause mortality after 30 days acute PE diagnosis up five years within consecutive sub-periods.Adult patients diagnosed with between January 1, 2003, June 30, 2013, were retrospectively included. Data on baseline characteristics during a five-year follow-up collected.The study included 414 (Male/Female=192/222). The median age at was 61.5 (minimum-maximum,...
Abstract Background Over-reliance on short-acting β 2 -agonists (SABAs) is associated with poor asthma outcomes. However, the extent of SABA use in Turkey unclear owing to a lack comprehensive healthcare databases. Here, we describe demographics, disease characteristics and treatment patterns from Turkish cohort IN Asthma (SABINA) III study. Methods This observational, cross-sectional study included patients aged ≥ 12 years 24 centres across Turkey. Data sociodemographics, treatments were...
CSF proteins in 107 children ranging from 3 to 24 months of age were analyzed by means quantitative zone electrophoresis on agarose gel. Subjects included 50 with infantile spasms, 41 without CNS disease serving as controls, and 16 infants acute aseptic meningitis who demonstrated the protein pattern blood-CSF barrier disturbance. Children spasms subdivided into several groups according etiological categories: symptomatic (pre-, peri-, postnatal), doubtful, cryptogenetic. Before any...
Pharmacotherapies for obstructive lung diseases are dependent on agents delivered via inhaler devices, and the correct technique is essential efficiency of these drugs.To determine rate incorrect techniques among patients with pulmonary efficacy delivering physician-provided training to by letting them practice their devices.Patients ages ≥18 years asthma, chronic disease, or asthma disease overlap syndrome were enrolled. At first visit, requested use own inhalers that they currently initial...
Aim: To determine the programmed death ligand-1 (PD-L1) expression rates in sarcomatoid lung carcinomas and to compare clinicopathologic features survival of PD-L1-positive negative patients. Methods: PD-L1 was evaluated 65 surgically resected carcinomas. The cases with tumors were compared. Kaplan-Meier analysis performed. Multiple Cox proportional hazard regression performed independent predictors overall survival. Results: antibody positivity found 72.3% Regarding histopathologic...
Background: Asthma control is defined as to what extent manifestations of asthma can be observed in a patient or have been reduced removed by treatment. Regular use treatments, correct inhaler technique, adequate information provided about the patient's diseases and medicines, patient-clinician collaboration aid control. shares risk factors links pathogenesis with obstructive sleep apnea (OSA), OSA may aggravate symptoms. Objective: To assess for Methods: The study was carried out subjects...
1. World Health Organization. WHO Report on the Global Tobacco Epidemic: Enforcing bans tobacco advertising, promotion and sponsorship. Geneva, Switzerland: Organization; 2013. https://apps.who.int/iris/bits.... Accessed August 24, 2016. Google Scholar
Asthma controller medications can be delivered via pressurized metered dose inhaler (pMDI) or dry powder (DPI) devices.
It is known that the prevalence of obstructive sleep apnea (OSA) increased in acromegaly. Craniofacial anomalies, macroglossia, and thickening laryngeal wall caused by increase soft tissue these patients lead to OSA. Also, growth hormone can trigger central causing a decrease respiratory drive. Determining polysomnographic characteristics acromegaly important reveal effect mechanisms.The demographic 33 who underwent polysomnography (PSG) with suspicion disorders between 2011 2018 laboratory...
Abstract Background This cost of illness study aimed to determine economic burden short-acting β2-agonist (SABA) overuse in Türkiye from payer perspective with respect the updated GINA 2022 treatment recommendations. Methods A total 3,034,879 asthma patients comprised population, via estimations extrapolated arm global SABINA III study. The (costs related drug use and severe exacerbations) was compared subgroups overall (≥ 0 canisters/year) vs. GINA-recommended (0–2 canisters/year,...
Background/aim: In our country, there is no data on whether the clinicians give an asthma action plan to implement patients followed up with a diagnosis of asthma, and can manage their treatment according this plan. The present study aimed determine use plans in country awareness levels about plan.Materials methods: Multicenter, cross-sectional descriptive was conducted outpatient immunology allergy pulmonology clinics secondary tertiary health-care centers. Adults asthmatics filled out case...
Until recently, the tuberculin skin test (TST) has been only assay used for detecting latent tuberculosis infection (LTBI), but two ex-vivo tests, as alternative methods to TST, based on enumerating M. tuberculosis-specific interferon (IFN)-\gamma response are now commercially licensed. The aim of this study was compare sensitivity and specificity QuantiFERON Gold (QFT-G), T-SPOT.TB in diagnosing LTBI active (TB). Materials methods: This carried out with 95 participants including 3 groups...
Failure to achieve high levels of medication adherence in obstructive lung diseases is a major cause uncontrolled disease. The purpose this study reveal clinicians' opinions on the level patient and change during COVID-19 pandemic.A questionnaire containing multiple-choice questions about treatment patients with was voluntarily applied doctors working tertiary hospital for chest diseases.Eighty-one (mean age, 37.2 years [standard deviation, 9.7 years]; 57 (70.4%) women) answered...
First step is to evaluate the quality of test in interpreting spirometries. International societies have defined acceptability criteria for spirometric tests. With this study, it was aimed tests terms compliance with international and determine error types.Spirometric manoeuvres held at a tertiary chest diseases hospital were evaluated as whether "American Thoracic Society/European Respiratory Society (ATS/ERS)" guideline maintained or not. Errors determined classified unexplosive start...
<b>Background and Aims:</b> Acute pulmonary embolism (PE) is a fatal disease. Our aim in this study was to determine early late all-cause mortality of acute PE patients their clinical, laboratory, imaging characteristics as potential predictors. <b>Methods:</b> Adult diagnosed with Hacettepe University Hospital between January 1, 2003 June 30, 2013 status were retrospectively analyzed. Parameters associated increased for each period analyzed age sex controlled univariate multivariate...
Amac: Bu calismada 14 – 16 yas voleybol ve tenis oyuncularinin gorsel isitsel reaksiyon zamanlarinin incelenmesi amaclandi. Gerec yontem: Calismaya sag eli dominant 12 oyuncusu toplam 24 saglikli erkek sporcu gonullu olarak katildi. Gonullulerin yas, boy uzunlugu, vucut agirligi, beden kutle indeksleri, zamanlari olculdu. Olcumler laboratuvar ortaminda arastirmacilar tarafindan gerceklestirildi. Elde edilen verilerin istatistiki analizi bilgisayar SPSS 15.0 programinda Mann Whitney U-testi...