A5088665108- Forensic and Genetic Research
- Molecular Biology Techniques and Applications
- Traditional Chinese Medicine Studies
- Forensic Anthropology and Bioarchaeology Studies
- Nutrition, Genetics, and Disease
- Genomic variations and chromosomal abnormalities
- Neurotransmitter Receptor Influence on Behavior
- Genetics, Bioinformatics, and Biomedical Research
- Race, Genetics, and Society
- Machine Learning in Bioinformatics
- Genomics and Chromatin Dynamics
- Metabolomics and Mass Spectrometry Studies
- Forensic Entomology and Diptera Studies
- Animal Disease Management and Epidemiology
- Alcohol Consumption and Health Effects
- Genetic Mapping and Diversity in Plants and Animals
- Blood groups and transfusion
- Adipose Tissue and Metabolism
- Ion channel regulation and function
- Cardiac electrophysiology and arrhythmias
- interferon and immune responses
- Genetic diversity and population structure
- Genetic Associations and Epidemiology
- RNA regulation and disease
- Neuroscience and Neuropharmacology Research
Guangdong Medical College
2006-2022
China University of Political Science and Law
2012
Shantou University
2008
Sichuan University
2001-2005
West China Medical Center of Sichuan University
2003
Abstract: To analyze the relationship between stature and hand dimensions for forensic applications, of 400 healthy adults aged 20 25 years were measured in a Han population Southern China. The mean values are 170.49 159.72 cm men women, respectively. statistically significant differences right‐ left‐hand not observed men, whereas bilateral female dimensions. correlation coefficients found to be both sexes. length showed higher than breadth Linear multiple regressions developed this study;...
To analyze linkage disequilibrium of 12 short tandem repeat loci on chromosome X (X-STR) among an ethnic Han population from Guilin, Guangxi, and to study the genetic haplotype distributions such in 2 groups.12 X-STR including DXS8378, DXS10159, DXS10162, DXS10164, DXS981, DXS6789, DXS7424, DXS101, DXS7133, GATA165B12, GATA31E08 DXS7423 were genotyped using AGCU X12 STR PCR Amplification kit. A total 119 pedigrees analyzed for disequilibrium.Two mutations found at 1 mutation was DXS10164. 93...
Methamphetamine (METH) is an illicit amphetamine-like psychostimulant that commonly abused. However, the modulation of METH-induced cardiac microvascular permeability still not completely known. Previously, we discovered vascular endothelial growth factor (VEGF) regulated cardiotoxicity produced by METH. In this work, looked into effect METH exposure on via VEGF-PI3K-Akt-eNOS signaling pathway, as well efficacy Bevacizumab treatment in reducing effect. The findings revealed enhanced while...
Objective To analyze genetic polymorphism of 15 STR loci in Nanning Han population,and to the population differentiation between and other Guangxi.Methods were genotyped by multiplex PGR.The distance analyzed using Arlequin 3.1 software,and phylogenetic tree 12 ethnic groups was constructed neighborjoining method.Results PIC values varied from 0.51 0.84,and DP 0.77 0.96,and PE valnes vailed 0.24 0.77.The non.difierentiation exact P value Was mole than 0.05 Hui,Jing Guangxi at TH01,and less...
To evaluate polymorphisms and forensic efficiency of 22 non-binary single nucleotide polymorphism (SNP) loci.One hundred ethnic Han Chinese individuals were recruited from Dongguan, Guangdong. The loci genotyped with matrix-assisted laser desorption/ionization time flight mass spectrometry (MALDI-TOF MS).Nine found a allele, 4 to be biallelic, whilst 9 have 3 alleles. For 13 polymorphic loci, the combined discrimination power exclusion 0.999 98 0.9330, respectively. non-biallelic 0.9998...
Objective To investigate the genetic polymorphisms of 15 short tandem repeat(STRs) in Guilin Han population. Methods DNA was extracted by Chelex method, and STRs were analyzed using AmpFISTR IdentifilerTM kit. Results Four rare alleles, namely FGA*10, D2S1338*10, D3S1358*16.2 D3S1358 * 17.2, observed. The combined match probability exclusion for 2.89×10-17 0. 9999993, respectively. Conclusion These have good discrimination power Hart population. Key words: short repeat; polymorphism; ...
Abstract Blood samples were collected from unrelated individuals of Chinese Han ethnic group in Chengdu China. DNA was extracted using Chelex method (1). PCR amplification conditions can be accessed at http://www.legalmed.org/dna/DXS6807.htm. The volume reaction for each locus 37.5 L. products analyzed by horizontal non-denaturing polyacrylamide gel electrophoresis with discontinuous buffer system and visualized silver staining (2). Data female population genetics forensic science POWERSTATS...
Abstract A total of 74 blood samples were collected from unrelated males Han ethnic group in Chongqing China. DNA was extracted by utilizing Chelex method (1). Each PCR reaction contained 2-10 ng DNA, 1 X Taq buffer, 1.5 mM MgCl2, 200 RM each dNTP (Pharmacia Biotech, Sweden), U polymerase (NEB, UK), 0.3 primer. amplifications performed a GeneAmp System 9600 (Perkin-Elmer, Foster City, CA),with denaturing for 2 min at 94°C, followed 30 cycles 94°C 50 s, 58°C s and 72°C s. products analyzed...
Abstract Whole blood obtained by venipuncture from 107 unrelated males of the Han ethnic group in Chengdu, China. DNA was extracted using Chelex method (1). The reaction volume PCR 37.5 μL, containing 2–4 ng human genome DNA, 200 μM each dNTP (Pharmacia, Sweden), 1.5μ Taq polymerase (Promega, Madison, WI), 3.75 μL 10 × buffer, Mg2+ 1.5 mM, 1.6 μg/mL BSA, 0.3 primer. Amplification reactions were carried out a Perkin Elmer 9600 (Foster City, CA) with pre-denaturing for 2 min at 94°C, followed...
Abstract A total of 101 blood samples were collected from unrelated males Tibetan ethnic group in Lasa China. DNA was extracted using Chelex method (1). The allelic variation at the three Y-STR loci named as DYS434, DYS443, and DYS456, analyzed by PCR amplication with multiplex system. Multiplex amplifications performed a 37.5 μL containing 2–4 ng human genome DNA, 7.5 dNTP (1 mmol/mL), 3μ, Taq polymerase, 3.75 10 × buffer (Mg2+ 1.5 mmol/l), BSA (1.6 μg/mL), 0.3 each primers (50 nmol/mL).
Abstract Specimens of 126 unrelated male individuals were collected from Han ethnic group in Sichuan province China. DNA was extracted blood specimens using Chelex 100 method (1). typing carried out by PCR. Each PCR reaction contained 2 to 20 ng human genomic DNA,1 × Taq buffer,1.5 mM MgCl2, 200 μM each nucleotide, 1.5 U polymerase, 0.25 primer a total volume 37.5 μL. In the Protocol initially denatured at 94°C for 1 min. This followed with 50 s, 63°C 70 and 72°C 7 s. A 38 cycles GenAmp...
Objective To investigate the frequencies of allele and haplotype 5 X-STR in Suzhou Han population,and to analyze linkage disequilibrium among loci.Methods Genomic DNA samples was extracted using Chelex method.All loci were amplified PCR,and genotyped automatic sequencer. Results A total 5,6,15,21 15 alleles at DXS7423,DXS10147,DXS10146,DXS10134 DXS8377 observed population,respectively. No significant difference allelic between females males found DXS7423(P=0.161),DXS10147(P=0.756)...
Objective To analyze the genetic polymorphism of 8 Y-STR loci in Han population Sichuan, and allelic sequences Y-STRs. Methods PCR products were genotyped using non-denatured polyacrylamide gel electrophoresis. Results DYS443, DYS453, DYS455, DYS456 are Y-STRs with simple repeat motif, DYS444, DYS448, DYS457, DYS458 complex motif. A total 106 haplotypes observed at 8-Y-STRs 108 males. The gene diversities ranged from 0. 355-0. 821, diversity haplotype was 9996. Conclusion discrimination...
POPULATION: One hundred and twenty unrelated Han ethnic individuals from Chengdu, southwest China.