A5058701265- Forensic and Genetic Research
- Molecular Biology Techniques and Applications
- Genetic diversity and population structure
- Race, Genetics, and Society
- Genetic Associations and Epidemiology
- Environmental DNA in Biodiversity Studies
- Forensic Anthropology and Bioarchaeology Studies
- Yersinia bacterium, plague, ectoparasites research
- Gene expression and cancer classification
- Genomics and Phylogenetic Studies
- Genital Health and Disease
- Genetic and phenotypic traits in livestock
- Hepatitis B Virus Studies
- Genetic Mapping and Diversity in Plants and Animals
- Animal Disease Management and Epidemiology
- Botanical Research and Chemistry
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Neurodegenerative Diseases
- interferon and immune responses
- Research Data Management Practices
- Data-Driven Disease Surveillance
- Radioactive contamination and transfer
- Nutrition, Genetics, and Disease
- Plant Disease Resistance and Genetics
Bundeskriminalamt
2024
Charité - Universitätsmedizin Berlin
2013-2022
Humboldt-Universität zu Berlin
2001-2022
Freie Universität Berlin
2022
Numerous studies of human populations in Europe and Asia have revealed a concordance between their extant genetic structure the prevailing regional pattern geography language. For native South Americans, however, such evidence has been lacking so far. Therefore, we examined relationship Y-chromosomal genotype on one hand, male geographic origin linguistic affiliation other, largest study American natives to date terms sampled individuals populations. A total 1,011 individuals, representing...
A total of 17 Y-specific STR loci were studied in 12 districts the European part Russia aiming to ascertain amount substructure required for construction a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis molecular variance. However, when Western is taken whole, genetic distances neighbouring populations significant. Whereas gradual change Y chromosome pool exists between and Slavic-speaking West,...
We present results from an inter-laboratory massively parallel sequencing (MPS) study in the framework of SeqForSTRs project to evaluate forensically relevant parameters, such as performance, concordance, and sensitivity, using a standardized library including reference material, mixtures, ancient DNA samples. The was prepared ForenSeq Signature Prep Kit (primer mix A). shared between eight European laboratories located Austria, France, Germany, Netherlands, Sweden perform MPS on their...
Abstract We describe here an online Y-chromosomal short tandem repeat haplotype reference database (YHRD) for U.S. populations, which represents 9-locus Y-STR haplotypes 1705 African-Americans, European-Americans and Hispanics as of October 2001. This is available (http://www.ystr. org/usa/), free to access was generated in order supply the forensic DNA community with a valuable resource frequencies complete or incomplete haplotypes, well information about typing protocols population genetic...
To evaluate the promising advantages of massively parallel sequencing (MPS) in our casework, we analysed a total 33 Y-chromosomal short tandem repeats (Y-STRs) with traditional capillary electrophoresis (CE) and 25 Y-STRs using newer MPS technology. We studied outcome both technologies 64 father-son pairs stock custom-designed kits. Current technology confirmed 13 mutational events observed CE improved understanding complex nature STR mutations. By detecting isometric sequence variants...