A5100436159- Escherichia coli research studies
- Bacteriophages and microbial interactions
- Bacterial Genetics and Biotechnology
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Enterobacteriaceae and Cronobacter Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Glycosylation and Glycoproteins Research
- Probiotics and Fermented Foods
- Genomics and Phylogenetic Studies
- Carbohydrate Chemistry and Synthesis
- Genetic Mapping and Diversity in Plants and Animals
- Antibiotic Resistance in Bacteria
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- Parasitic Infections and Diagnostics
- Yersinia bacterium, plague, ectoparasites research
- Plant Virus Research Studies
- Neurological Disease Mechanisms and Treatments
- Microbial Metabolic Engineering and Bioproduction
- Chromosomal and Genetic Variations
- Bacterial Infections and Vaccines
- Sesame and Sesamin Research
- Biosensors and Analytical Detection
Nankai University
2016-2025
Shanghai Jiao Tong University
2022-2025
Northwest A&F University
2014-2025
South China Normal University
2025
Anhui University of Science and Technology
2024
Ministry of Education of the People's Republic of China
2013-2024
Henan Institute of Science and Technology
2021-2024
Xiamen University of Technology
2024
Guangxi University of Chinese Medicine
2024
Nanchang Institute of Technology
2023-2024
In the early 1990s an outbreak of papaya ringspot virus (PRSV) in groves Puna district Hawaii caused severe damage to important crop. Since then, planting two transgenic cultivars resistant — called 'SunUp' and 'Rainbow' has helped maintain yields. SunUp is a red-fleshed fruit that expresses coat protein gene mild mutant PRSV, conferring resistance via post-transcriptional silencing. Rainbow yellow-fleshed (and therefore more popular) F1 hybrid bred from SunUp. Now draft genome sequence...
Crustacea, the subphylum of Arthropoda which dominates aquatic environment, is major importance in ecology and fisheries. Here we report genome sequence Pacific white shrimp Litopenaeus vannamei, covering ~1.66 Gb (scaffold N50 605.56 Kb) with 25,596 protein-coding genes a high proportion simple repeats (>23.93%). The expansion related to vision locomotion probably central its benthic adaptation. Frequent molting may be explained by an intensified ecdysone signal pathway through gene...
The complete genome sequence of Geobacillus thermodenitrificans NG80-2, a thermophilic bacillus isolated from deep oil reservoir in Northern China, consists 3,550,319-bp chromosome and 57,693-bp plasmid. reveals that NG80-2 is well equipped for adaptation into wide variety environmental niches, including reservoirs, by possessing genes utilization broad range energy sources, encoding various transporters efficient nutrient uptake detoxification, flexible respiration system an aerobic branch...
Growth and development of a plant are controlled by programmed expression suits genes at the appropriate time, tissue abundance. Although genomic resources have been developed rapidly in recent years rice, model for cereal genome research, data gene profiling still insufficient to relate developmental processes transcriptomes, leaving large gap between sequence phenotype. In this study, we generated genome-wide hybridizing 190 Affymetrix GeneChip Rice Genome Arrays with RNA from 39 tissues...
Abstract Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S . exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on synthesis are mediated bacterial protein SopE2, a type III secretion system (T3SS) effector encoded pathogenicity island SPI-1. changes metabolism promote intracellular replication via two mechanisms: glucose levels...
Hybrid sterility is a major form of postzygotic reproductive isolation. Although isolation has been key issue in evolutionary biology for many decades wide range organisms, only very recently few genes were identified. The Asian cultivated rice (Oryza sativa L.) divided into two subspecies, indica and japonica. Hybrids between japonica varieties are usually highly sterile. A special group germplasm, referred to as wide-compatibility varieties, able produce fertile hybrids when crossed both...
Nematode-trapping fungi are "carnivorous" and attack their hosts using specialized trapping devices. The morphological development of these traps is the key indicator switch from saprophytic to predacious lifestyles. Here, genome nematode-trapping fungus Arthrobotrys oligospora Fres. (ATCC24927) was reported. contains 40.07 Mb assembled sequence with 11,479 predicted genes. Comparative analysis showed that A. shared many more genes pathogenic than non-pathogenic fungi. Specifically, compared...
The identification and phylogenetic relationships of bacteria within the Bacillus cereus group are controversial. This study aimed at determining taxonomic affiliations these strains using whole-genome sequence-based Genome BLAST Distance Phylogeny (GBDP) approach. GBDP analysis clearly separated 224 into 30 clusters, representing eleven known, partially merged species accordingly 19-20 putative novel species. Additionally, 16S rRNA gene analysis, a variant multi-locus sequence (nMLSA)...
Abstract Background Hevea brasiliensis, a member of the Euphorbiaceae family, is major commercial source natural rubber (NR). NR latex polymer with high elasticity, flexibility, and resilience that has played critical role in world economy since 1876. Results Here, we report draft genome sequence H. brasiliensis . The assembly spans ~1.1 Gb estimated 2.15 haploid genome. Overall, ~78% was identified as repetitive DNA. Gene prediction shows 68,955 gene models, which 12.7% are unique to Most...
Apart from sharing common ancestry with chordates, sea cucumbers exhibit a unique morphology and exceptional regenerative capacity. Here we present the complete genome sequence of an economically important cucumber, A. japonicus, generated using Illumina PacBio platforms, to achieve assembly approximately 805 Mb (contig N50 190 Kb scaffold 486 Kb), 30,350 protein-coding genes high continuity. We used this resource explore key genetic mechanisms behind biological characters cucumbers....
Significance Cholera, a major disease in human history, has terrorized the world through seven pandemics. The seventh pandemic started Indonesia 1961 and spread globally, currently infecting 3–5 million people annually. By combining all available historical records genomic analysis of preseventh some early strains, we revealed complex six-step evolution strain from its probable origin South Asia to nonpathogenic form Middle East ∼1900 ∼1925, where it evolved into before becoming widespread...
We elucidate grapevine evolution and domestication histories with 3525 cultivated wild accessions worldwide. In the Pleistocene, harsh climate drove separation of grape ecotypes caused by continuous habitat fragmentation. Then, occurred concurrently about 11,000 years ago in Western Asia Caucasus to yield table wine grapevines. The domesticates dispersed into Europe early farmers, introgressed ancient western ecotypes, subsequently diversified along human migration trails muscat unique...
We investigated the hypothesis that endothelial cells activated by erythropoietin (EPO) promote migration of neuroblasts. This is based on observations in vivo treatment focal cerebral ischemia with EPO enhances neuroblasts to ischemic boundary, a site containing and angiogenic microvasculature. To model microenvironment within boundary zone, we used coculture system mouse brain (MBECs) neural progenitor derived from subventricular zone adult mouse. Treatment MBECs recombinant human (rhEPO)...
Abstract Background The phylum Verrucomicrobia is a widespread but poorly characterized bacterial clade. Although cultivation-independent approaches detect representatives of this in wide range environments, including soils, seawater, hot springs and human gastrointestinal tract, only few have been isolated pure culture. We recently reported cultivation initial characterization an extremely acidophilic methanotrophic member the , strain V4, from Hell's Gate geothermal area New Zealand....
ABSTRACT The O157:H7 clone of Escherichia coli , which causes major, often prolonged outbreaks gastroenteritis with hemolytic-uremic syndrome (HUS) such as those in Japan, Scotland, and the United States recently, is thought to be resident normally cattle or other domestic animals. This major significance for public health food industry. We have developed a fast method sequencing given O antigen gene cluster applied it O157. O157 14 kb length, comprising 12 genes remnant H-repeat unit. Based...
Mortierella alpina is an oleaginous fungus which can produce lipids accounting for up to 50% of its dry weight in the form triacylglycerols. It used commercially production arachidonic acid. Using a combination high throughput sequencing and lipid profiling, we have assembled M. genome, mapped lipogenesis pathway determined major species. The 38.38 Mb genome shows degree gene duplications. Approximately 12,796 models, 60% genes predicted pathway, belong multigene families. Notably, has 18...
Cholera, caused by Vibrio cholerae, erupted globally from South Asia in 7 pandemics, but there were also local outbreaks between the 6th (1899–1923) and 7th (1961–present) pandemics. All above are serotype O1, whereas environmental or invertebrate isolates antigenically diverse. The pre pandemic mentioned above, other minor pathogenic clones, related to clone, while clone is same lineage more distantly related, non-pathogenic show no clonal structure. To understand origins relationships of...