Low-grade gliomas (LGG), approximately constitute one-third of all types gliomas, are prone to relapse and metastasis. MicroRNA-138 (miR-138) is reported be dysregulated in diverse human tumors mainly function as a tumor suppressor. In this study, we analyzed the expression profile miR-138 LGG.Quantitative PCR (qPCR) public database bioinformatics analysis were performed determine levels LGG. MiR-138 overexpression LGG cells was achieved by mimics transfection. Cell proliferation assessed...

Prospero homeobox protein 1 (PROX1) is highly expressed in high-grade malignant astrocytic gliomas. However, the role of PROX1 pathogenesis glioblastoma multiforme (GBM) remains unclear. The present study overexpressed human GBM cell lines and examined its effects on growth, tumorigenesis, invasiveness. In addition, involvement nuclear factor‑κB (NF‑κB) signaling pathway action was examined. It identified that overexpression significantly increased proliferation colony formation cells,...

The important indicators to measure the goodness of rigid fruit and vegetable picking robot have two aspects, first is reasonable structural design end-effector, second having a high precision positioning recognition method. Many researchers done lot work in these variety end-effector structures advanced position methods are constantly appearing people's view. working principle, characteristics, advantages disadvantages each summarized help us better robot. authors start from grasping...

Malignant melanoma (MM) is caused by melanophore cancerization in tissue pigmentation regions, leading to skin, mucous membrane, eye and central nervous system carcinogenesis. The incidence of MM has increased previous years, it become the primary cause skin cancer‑associated mortality developed countries. characterized as highly malignant readily metastasized, a poor prognosis. Targeting angiogenesis an important method for treatment. As proangiogenic factor tumor growth metastasis,...

The present study aimed to investigate the clinicopathological features of cases classic Kaposi's sarcoma (CKS) in Xinjiang Uygur Autonomous Region, China, and analyze its etiology treatment. A total 114 patients, who were clinicopathologically diagnosed with CKS at First Affiliated Hospital Medical University (Urumqi, China) between 1980 2015 retrospectively analyzed. summarized, demographic distribution, pathogenesis, treatment examined. results revealed that, among patients CKS, 100 men...

This work was to investigate mechanism by which mir-22 targeting nod-like receptor protein 3 (NLRP3) inflammasome affected activity of human skin malignant melanoma (MM) A375 cells. Twenty-four mice were rolled into a control group (Group X) and an experimental Y) randomly. Without treatment in Group X, Y established MM model. After cell transfection, the divided A (blank group), B (negative C (miR-22 mimics D inhibitor E inhibitor+siNLRP3 group). The results summarized as follows. level...

Background: Acral Lentiginous Melanoma (ALM), a rare but aggressive form of cutaneous melanoma, affects about 2-3% melanoma patients in Western populations. It primarily targets acral areas like palms, soles, and subungual regions, is more common individuals with darker skin tones. ALM’s unique biological molecular properties, coupled delayed diagnosis lack awareness, contribute to its nature poorer prognosis compared other types. Our goal was explore the surgical management ALM by analyzing...

The present study investigated the expression of Toll-like receptor 4 (TLR4) and proteins involved in its associated signaling pathways patients with classic Kaposi's sarcoma (KS) acquired immune deficiency syndrome (AIDS)-associated KS (AIDS-KS) Xinjiang Autonomous Region China. A total 35 were enrolled between May 2011 July 2013, including 26 cases AIDS-KS 9 KS. Another 10 healthy subjects Uygur ethnic group included normal control group. tissues subjected to hematoxylin eosin staining...

Background: Invasive fungal infection received more and attention because of its high mortality, Candida albicans Aspergillus fumigatus is the most common pathogenic fungus for systematic infection, A. lentulus was isolated identified recently named as a sister fumigatus. Objectives: The current study aimed to explore concentration time-dependent relationships virulence fungi due change in Interleukin-1 beta (IL-1β) level. Methods: albicans, fumigatus, suspensions with multiplicity = 0, 1,...

The main improvement of image steganography is that it can generate dense images with high visual quality. generated countermeasure network based on least squares more stable than the conventional and converges faster WGAN. work generation to replace cross-entropy loss function function. This considered improve two problems traditional Gan, is, quality by Gan not high, training process very unstable. attempts use different distance metrics build a stable, convergent high-quality network. In...

Objective To analyze the clinical features of AIDS-related Kaposi's sarcoma (AIDS-KS) patients in Xinjiang uygur autonomous region, and to evaluate efficacy highly active antiretroviral therapy (HAART) systemic chemotherapy. Methods Clinical data on 70 AIDS-KS admitted Sixth People's Hospital Uygur Autonomous Region from January 2008 June 2013 were reviewed. The demographic characteristics, progress KS, extent lesions, treatment prognosis these retrospectively studied. different...

Background: Cutaneous Malignant Melanoma (CMM) is a formidable global health challenge, exhibiting distinct characteristics in China. While extensively studied Western countries, the unique epidemiological patterns, clinical manifestations, and diagnostic challenges of CMM Chinese demographic remain underexplored. This study aims to unravel complexities within China, drawing insights from recent investigation at First Affiliated Hospital Xinjiang Medical University. Methods: A retrospective...

As a branch of computer image vision technology, video intelligent analysis has been widely used in the field security, which plays an important role operation monitoring, fault analysis, early warning automation and information processing power grid industry. In order to improve low efficiency artificial patrol mode existing substation surveillance system, this paper designs system for scene anomalies based on convolutional neural network. Firstly,the architecture is analyzed. Secondly,...

Objective To explore the incidence and clinical features of traumatic brain injury (TBI) so as to provide some reference for making preventive control measures. Methods Influence factors 3960 TBI patients, such age, sex, occupation, mechanisms, time distribution, information, treatments results on were retrospectively analyzed. Results Among cases, males females ratio was 3.5∶1, major victim 20-49 years old, workers (35.3%), farmers (26.4%) students (9.8%) top 3 occupations. mostly happened...

Objective To further clarify the pathogenesis of different types Kaposi′s sarcoma (KS) by measuring protein expressions caspase-3 and E-cad in tumor tissues Xinjiang Uygur patients with acqured immunodeficiency syndrome (AIDS)-Kaposi′s classical KS. Methods From July 2011 to October 2014, 38 KS at First Affiliated Hospital Medical University Urumqi Infectious Disease were enrolled, among whom 28 male 10 female, all them uygur. Immunohistochemical Western blot methods used detect...

<p class="abstract">In the past ten years, occurrence of basal cell carcinoma (BCC) has amplified manifold. There are many treatment procedures to cure BCC, which includes micrographic surgery by means surgical margins 3-5mm based on size tumor, intrusion and location. The normally used method for is excision surgery. most commonly advanced in bcc Mohs’ (MMS). no proper guideline, mentions as choice there controlled randomized studies matching with nonsurgical options BCC. Excision a...