David Lukáš

ORCID: 0000-0003-4037-6435
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About
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced Sensor and Energy Harvesting Materials
  • Tissue Engineering and Regenerative Medicine
  • Electrohydrodynamics and Fluid Dynamics
  • Textile materials and evaluations
  • Silk-based biomaterials and applications
  • Bone Tissue Engineering Materials
  • Conducting polymers and applications
  • Surface Modification and Superhydrophobicity
  • Thyroid Cancer Diagnosis and Treatment
  • Material Properties and Processing
  • biodegradable polymer synthesis and properties
  • Lattice Boltzmann Simulation Studies
  • Additive Manufacturing and 3D Printing Technologies
  • Supercapacitor Materials and Fabrication
  • Polymer Nanocomposite Synthesis and Irradiation
  • Osteoarthritis Treatment and Mechanisms
  • Carbon Nanotubes in Composites
  • Particle physics theoretical and experimental studies
  • Thyroid and Parathyroid Surgery
  • Fiber-reinforced polymer composites
  • Aerosol Filtration and Electrostatic Precipitation
  • 3D Printing in Biomedical Research
  • Neutrino Physics Research
  • Hernia repair and management

Technical University of Liberec
2016-2025

University Hospital Regensburg
2025

Charles University
2012-2019

University Hospital Kralovske Vinohrady
2012-2016

University of Hawaiʻi at Mānoa
2014

University of Hawaii System
2014

General University Hospital in Prague
2010

Clemson University
2010

Kiel University
2002

Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
2001

The broader application of liposomes in regenerative medicine is hampered by their short half-life and inefficient retention at the site application. These disadvantages could be significantly reduced combination with nanofibers. We produced 2 different nanofiber-liposome systems present study, that is, blended within nanofibers core/shell embedded liposomes. Herein, we demonstrate blend electrospinning does not conserve intact In contrast, coaxial enables incorporation into report polyvinyl...

10.1021/bm2018118 article EN Biomacromolecules 2012-03-08

Electrospinning has enabled creation of excellent materials for a great number applications. Previously, it was based on less productive capillary spinners. The present study is recent efforts to elevate electrospinning technology an industrial level by simultaneously provoking innumerable polymeric jets from sufficiently large liquid surface increase productivity. Particularly, deals with free conductive liquids and validates formulated hypothesis that explains self-organization...

10.1063/1.2907967 article EN Journal of Applied Physics 2008-04-15

The history of electrospinning is briefly introduced at the beginning article. fundaments process are then analysed physically to be translated into a successful technology. Self-organisation fluid in perceived as consequence various instabilities, based on electrohydrodynamics and, thus, highlighted key factor, theorising subject successfully elevate it highly productive technology manufacture nano-scale materials. main physical principle self-organisation appearance unstable tiny capillary...

10.1080/00405160902904641 article EN Textile Progress 2009-05-14

This study describes the application of a new technological parameter in alternating-current (AC) electrospinning process for enhancing electrospinnability and productivity polycaprolactone (PCL) electrospun nanofibers (ENF). High-voltage AC is influenced via changes both waveform frequency; however, overall contribution to PCL remains unclear. hypothesizes that electrospinnability, morphology, diameter ENF are dependent on frequency high-voltage signal. Thus, paper demonstrates...

10.1016/j.matdes.2021.110308 article EN cc-by-nc-nd Materials & Design 2021-12-08

Composite nanofibrous yarns (CNY), featuring a submicron electrospun sheath coated on micro-scale core yarn have gained attention within the academic and industrial communities due to their unique structure. When braided, these CNYs hold great promise as next-generation surgical yarns. However, large-scale production of using conventional electrospinning techniques remains technologically challenging, maintaining integrity fibrous during braiding presents further difficulties. Here, we...

10.1016/j.coco.2024.101932 article EN cc-by Composites Communications 2024-05-08

Abstract Aims Semaglutide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has shown promising effects in reducing cardiovascular events patients with obesity and heart failure (HF) preserved ejection fraction (HFpEF) irrespective of concomitant diabetes. However, the exact mechanisms underlying its cardioprotective actions remain unclear. Our study investigates direct semaglutide on human cardiomyocytes, focusing calcium (Ca) sodium (Na) handling potential to improve myocardial...

10.1002/ejhf.3644 article EN cc-by European Journal of Heart Failure 2025-03-19

Nanofibrous materials are essential components for a wide range of applications, particularly in the fields medicine and material engineering. These include protective materials, sensors, cosmetics, hygiene, filtration energy storage. The most widely used researched technology these is electrospinning. This method producing fibers yields highly promising results thanks to its versatility simplicity. Electrospinning employed multiple forms, among which needle needleless direct current (DC)...

10.1039/c4cp04346d article EN Physical Chemistry Chemical Physics 2014-01-01

Abstract Objectives We prepared 3D poly (ε‐caprolactone) ( PCL ) nanofibre scaffolds and tested their use for seeding, proliferation, differentiation migration of mesenchymal stem cell MSC s). Materials methods nanofibres were using a special collector common electrospinning; simultaneously, 2D layer was classic plain collector. Both seeded with s biologically tested. adhesion, migration, proliferation osteogenic investigated. Results The scaffold characterized by having better biomechanical...

10.1111/cpr.12001 article EN Cell Proliferation 2012-12-07

Abstract Nanotechnologies allow the production of yarns containing nanofibres for use in composites, membranes and biomedical materials. Composite with a conventional thread core mechanical strength nanofibrous envelope functionality, e.g. biological, catalytic, have many advantages. Until now, such has been technologically difficult. Here, we show an approach to composite yarn whereby plume nanofibers generated by high throughput AC needleless collectorless electrospinning is wound around...

10.1038/s41598-019-38557-z article EN cc-by Scientific Reports 2019-02-12

Crystalline properties of semicrystalline polymers are very important parameters that can influence the application area. The internal structure, like mentioned crystalline properties, be influenced by production technology itself and changing parameters. present work is devoted to testing electrospun centrifugal spun fibrous nanofibrous materials compare them foils granules made from same raw polymer. test setup reveals structural differences caused technology. Effects average molecular...

10.1155/2017/8952390 article EN Journal of Nanomaterials 2017-01-01

Wet electrospinning is a useful method for 3-dimensional structure control of nanofibrous materials.This innovative technology uses liquid collector instead the metal one commonly used standard electrospinning.The article compares internal structural features polycaprolactone (PCL) materials prepared by both technologies.We analyze influence different water/ethanol compositions as on morphology resultant materials.Scanning electron micro-photographs have revealed bimodal in wet electrospun...

10.3144/expresspolymlett.2014.59 article EN publisher-specific-oa eXPRESS Polymer Letters 2014-01-01

We describe a method of fabrication nanoporous flexible probes which work as artificial proboscises. The challenge making with fast absorption rates and good retention capacity was addressed theoretically experimentally. This shows that the probe should possess two levels pore hierarchy: nanopores are needed to enhance capillary action micrometer pores required speed up fluid transport. model controlled verified in experiments. also demonstrated proboscises can be remotely by electric or...

10.1039/c1nr10773a article EN Nanoscale 2011-01-01

Additive manufacturing, also called 3D printing, is an effective method for preparing scaffolds with defined structure and porosity. The disadvantage of the technique excessive smoothness printed fibers, which does not support cell adhesion. In present study, a scaffold was combined electrospun classic or structured nanofibers to promote Structured were used improve infiltration cells into scaffold. Electrospun layers connected fibers by gluing, thus enabling fabrication unlimited thickness....

10.1080/19336918.2017.1385713 article EN Cell Adhesion & Migration 2017-11-13
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