A5024878074- Neuroendocrine regulation and behavior
- Olfactory and Sensory Function Studies
- Reproductive System and Pregnancy
- COVID-19 Impact on Reproduction
- Neurobiology and Insect Physiology Research
- Photoreceptor and optogenetics research
- Gut microbiota and health
- Developmental Biology and Gene Regulation
- Tryptophan and brain disorders
- Neuroscience and Neural Engineering
- Stress Responses and Cortisol
- Adolescent and Pediatric Healthcare
- Pluripotent Stem Cells Research
- Hypothalamic control of reproductive hormones
- Biochemical Analysis and Sensing Techniques
- Neurogenesis and neuroplasticity mechanisms
- COVID-19 and healthcare impacts
- Neural dynamics and brain function
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Advanced Chemical Sensor Technologies
- Adenosine and Purinergic Signaling
- Infant Nutrition and Health
- COVID-19 Clinical Research Studies
- Genetics and Neurodevelopmental Disorders
Massachusetts Institute of Technology
2015-2024
McGovern Institute for Brain Research
2015-2018
Columbia University
2018
Howard Hughes Medical Institute
2002-2011
California Institute of Technology
2002-2005
University of California, Berkeley
2001
Viral infection during pregnancy has been correlated with increased frequency of autism spectrum disorder (ASD) in offspring. This observation modeled rodents subjected to maternal immune activation (MIA). The cell populations critical the MIA model have not identified. Using both genetic mutants and blocking antibodies mice, we show that retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt)-dependent effector T lymphocytes [for example, helper 17 (TH17) cells] cytokine...
To understand the underlying mechanisms of progressive neurophysiological phenomena, neural interfaces should interact bi-directionally with brain circuits over extended periods time. However, such remain limited by foreign body response that stems from chemo-mechanical mismatch between probes and tissues. address this challenge, we developed a multifunctional sensing actuation platform consisting multimaterial fibers intimately integrated within soft hydrogel matrix mimicking tissue. These...
Abstract The ability to target subclasses of neurons with defined connectivity is crucial for uncovering neural circuit functions. olfactory (piriform) cortex thought generate odour percepts and memories, information encoded in piriform routed brain areas involved multimodal sensory integration, cognition motor control. However, it remains unknown if outputs are spatially organized, distinct output channels delineated by different gene expression patterns. Here we identify genes selectively...